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浏览/检索结果: 共9条，第1-9条 帮助 已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Novel Mcl-1/Bcl-2 Dual Inhibitors Created by the Structure-Based Hybridization of Drug-Divided Building Blocks and a Fragment Deconstructed from a Known Two-Face BH3 Mimetic 期刊论文 ARCHIV DER PHARMAZIE, 2015, 卷号: 348, 页码: 89-99 作者:  Zhang, Zhichao;  Su, Pengchen;  Li, Xiangqian;  Song, Ting;  Chai, Gaobo 收藏  |  浏览/下载：3/0  |  提交时间：2019/12/09 alpha-Helix  Drug-divided building blocks  Fragment-based  Mcl-1  Bcl-2   Two-Face, Two-Turn alpha-Helix Mimetics Based on a Cross-Acridine Scaffold: Analogues of the Bim BH3 Domain 期刊论文 CHEMBIOCHEM, 2014, 卷号: 15, 期号: 9, 页码: 1280-1285 作者:  Li, Xiangqian;  Wang, Ziqian;  Feng, Yingang;  Song, Ting;  Su, Pengchen 收藏  |  浏览/下载：27/0  |  提交时间：2015/11/02 acridines  helical structures  Mcl-1  peptidomimetics  two-face   Two-Face, Two-Turn alpha-Helix Mimetics Based on a Cross-Acridine Scaffold: Analogues of the Bim BH3 Domain 期刊论文 CHEMBIOCHEM, 2014, 卷号: 15, 页码: 1280-1285 作者:  Li, Xiangqian;  Wang, Ziqian;  Feng, Yingang;  Song, Ting;  Su, Pengchen 收藏  |  浏览/下载：10/0  |  提交时间：2019/12/09 acridines  helical structures  Mcl-1  peptidomimetics  two-face   3-Thiomorpholin-8-oxo-8H-acenaphtho [1,2-b] pyrrole-9-carbonitrile (S1) derivatives as pan-Bcl-2-inhibitors of Bcl-2, Bcl-x(L) and Mcl-1 (vol 21, pg 11, 2013) 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY, 2014, 卷号: 22, 页码: 663-664 作者:  Song, Ting;  Li, Xiangqian;  Yang, Ying;  Wu, Guiye;  Xie, Shenghui 收藏  |  浏览/下载：4/0  |  提交时间：2019/12/09 Design, synthesis and structure-activity relationship studies of morpholino-1H-phenalene derivatives that antagonize Mcl-1/Bcl-2 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY, 2014, 卷号: 22, 页码: 5738-5746 作者:  Li, Xiangqian;  Liang, Xiaomeng;  Song, Ting;  Su, Pengchen;  Zhang, Zhichao 收藏  |  浏览/下载：9/0  |  提交时间：2019/12/09 Dual inhibitors  Hydrogen bond  Apoptosis  Mcl-1  Bcl-2   3-Thiomorpholin-8-oxo-8H-acenaphtho [1,2-b] pyrrole-9-carbonitrile (S1) derivatives as pan-Bcl-2-inhibitors of Bcl-2, Bcl-x(L) and Mcl-1 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY, 2013, 卷号: 21, 期号: 1, 页码: 11-20 作者:  Song, Ting;  Li, Xiangqian;  Chang, Xilong;  Liang, Xiaomeng;  Zhao, Yan 收藏  |  浏览/下载：26/0  |  提交时间：2015/11/02 Pan-Bcl-2 inhibitor  Bcl-2  Mcl-1  p4 Pocket  Apoptosis   Study of binding thermodynamics in the optimization of BH3 mimetics. 2013, 82, 4, 394–400 期刊论文 Chem. Biol. Drug Des., 2013, 卷号: 82, 页码: 394-400 作者:  Zhang ZC(张志超);  Zhao Y(赵燕);  Song T(宋婷);  Liu, Yubo;  Li, Xiangqian 收藏  |  浏览/下载：4/0  |  提交时间：2019/12/13 3-Thiomorpholin-8-oxo-8H-acenaphtho [1,2-b] pyrrole-9-carbonitrile (S1) derivatives as pan-Bcl-2-inhibitors of Bcl-2, Bcl-x(L) and Mcl-1 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY, 2013, 卷号: 21, 页码: 11-20 作者:  Song, Ting;  Li, Xiangqian;  Chang, Xilong;  Liang, Xiaomeng;  Zhao, Yan 收藏  |  浏览/下载：6/0  |  提交时间：2019/12/11 Pan-Bcl-2 inhibitor  Bcl-2  Mcl-1  p4 Pocket  Apoptosis   Study of Binding Thermodynamics in the Optimization of BH3 Mimetics 期刊论文 CHEMICAL BIOLOGY & DRUG DESIGN, 2013, 卷号: 82, 页码: 394-400 作者:  Zhang, Zhichao;  Zhao, Yan;  Song, Ting;  Liu, Yubo;  Li, Xiangqian 收藏  |  浏览/下载：3/0  |  提交时间：2019/12/11 enthalpy  entropy  Gibbs free energy  hydrogen bond  isothermal titration calorimetry  thermodynamics