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科研机构
上海药物研究所 [4]
武汉大学 [4]
北京航空航天大学 [2]
内容类型
期刊论文 [10]
发表日期
2020 [4]
2019 [1]
2018 [2]
2017 [2]
2016 [1]
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Structure-based drug optimization and biological evaluation of tetrahydroquinolin derivatives as selective and potent CBP bromodomain inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 22, 页码: 7
作者:
Bi, Xiaoyang
;
Chen, Yu
;
Sun, Zhongya
;
Lu, Wenchao
;
Xu, Pan
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/05/24
Drug design
CBP
Bromodomain
Inhibitor
Acute myeloid leukemia
Design, synthesis, and biological evaluation of tetrahydroquinolin derivatives as potent inhibitors of CBP bromodomain
期刊论文
BIOORGANIC CHEMISTRY, 2020, 卷号: 101, 页码: 11
作者:
Chen, Yu
;
Bi, Xiaoyang
;
Zhang, Fengcai
;
Sun, Zhongya
;
Xu, Pan
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/12/24
In silico screening
Drug design
CBP
Bromodomain
Inhibitor
Acute Myeloblastic Leukemia
Covalent Inhibitors Allosterically Block the Activation of Rho Family Proteins and Suppress Cancer Cell Invasion
期刊论文
ADVANCED SCIENCE, 2020, 页码: 13
作者:
Sun, Zhongya
;
Zhang, Hao
;
Zhang, Yuanyuan
;
Liao, Liping
;
Zhou, Wen
收藏
  |  
浏览/下载:107/0
  |  
提交时间:2020/07/01
anti-metastasis activities
crystal structures
inhibitors
novel pockets
rho family proteins
discoveryofnovelcbpbromodomaininhibitorsthroughtrfretbasedhighthroughputscreening
期刊论文
actapharmacologicasinica, 2020, 卷号: 41, 期号: 2, 页码: 285
作者:
Zhang Fengcai
;
Sun Zhongya
;
Liao Liping
;
Zuo Yu
;
Zhang Dan
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2020/07/01
CBP bromodomain
small-molecule inhibitor
high-throughput screening
TR-FRET
molecular modeling
human leukemia MV4-11 cells
Differential microRNA expression profiles determined by next-generation sequencing in three fulvestrant-resistant human breast cancer cell lines
期刊论文
ONCOLOGY LETTERS, 2019, 卷号: 17, 期号: 4
作者:
Guo, Juan
;
He, Keli
;
Zeng, Hui
;
Shi, Yu
;
Ye, Peng
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/05
microRNA
breast cancer
MCF-7
fulvestrant
resistance
Differential microRNA expression profiles in tamoxifen-resistant human breast cancer cell lines induced by two methods
期刊论文
ONCOLOGY LETTERS, 2018, 卷号: 15, 期号: 3
作者:
Ye, Peng
;
Fang, Cheng
;
Zeng, Hui
;
Shi, Yu
;
Pan, Zhongya
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/05
microRNA
breast cancer
MCF-7
tamoxifen
resistance
Accuracy-enhanced constitutive parameter identification using virtual fields method and special stereo-digital image correlation
期刊论文
OPTICS AND LASERS IN ENGINEERING, 2018, 卷号: 103, 页码: 55-64
作者:
Zhang, Zhongya
;
Pan, Bing
;
Grediac, Michel
;
Song, Weidong
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/30
Special stereo-digital image correlation
Virtual fields method
Inverse method
Association Between MGMT Promoter Methylation and Breast Cancer: a Meta-Analysis
期刊论文
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 2017, 卷号: 42, 期号: 6
作者:
An, Nairui
;
Shi, Yu
;
Ye, Peng
;
Pan, Zhongya
;
Long, Xinghua
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/05
Mgmt
Breast Cancer
Methylation
Metastasis
Diagnosis
In-situ bending behavior and failure characterization of 3D needle-punched C/SiC composites
期刊论文
MATERIALS TODAY COMMUNICATIONS, 2017, 卷号: 13, 页码: 378-385
作者:
Dong, Yali
;
Shi, Xiaolei
;
Zhang, Zhongya
;
Pan, Bing
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/30
3D needle-punched C/SiC
Digital image correlation
Bending behavior
Failure mechanism
Deformation
SATB1 is Correlated with Progression and Metastasis of Breast Cancers: A Meta-Analysis
期刊论文
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 2016, 卷号: 38, 期号: 5
作者:
Zhang, Li
;
He, Keli
;
Long, Xinghua
;
Pan, Zhongya
;
Jing, Wei
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/05
SATB1
Breast Cancer
Metastasis
Prognosis
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