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科研机构
湖南农业大学 [4]
上海中医药大学 [3]
深圳先进技术研究院 [1]
上海药物研究所 [1]
中南大学 [1]
上海大学 [1]
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期刊论文 [11]
会议论文 [1]
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2018 [2]
2017 [3]
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Focal Cerebral Ischemia and Reperfusion Induce Brain Injury Through alpha 2 delta-1-Bound NMDA Receptors
期刊论文
STROKE, 2018, 卷号: 49, 期号: 10
作者:
Luo, Yi
;
Ma, Huijie
;
Zhou, Jing-Jing
;
Li, Lingyong
;
Chen, Shao-Rui
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/05
brain ischemia
caspase 3
gabapentin
hippocampus
neurons
NMDA receptor
pregabalin
The α2δ-1-NMDA Receptor Complex Is Critically Involved in Neuropathic Pain Development and Gabapentin Therapeutic Actions
期刊论文
Cell Reports, 2018, 卷号: 22, 期号: 9, 页码: 2307-2321
作者:
Chen, Jinjun
;
Li, Lingyong
;
Chen, Shao-Rui
;
Chen, Hong
;
Xie, Jing-Dun
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/23
*chronic pain
*dorsal root ganglion
*glutamate
*pregabalin
*presynaptic
*synaptic plasticity
*synaptic trafficking
*synaptic transmission
*thrombospondin
*voltage-gated calcium channels
Hepatotoxicity induced by radix Sophorae tonkinensis in mice and increased serum cholinesterase as a potential supplemental biomarker for liver injury
期刊论文
EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY, 2017, 卷号: 69, 期号: 4
作者:
Wang, Liping
;
Lu, Jinyao
;
Sun, Wei
;
Gu, Yingmin
;
Zhang, Chaochao
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/05
Radix Sophorae tonkinensis
Hepatotoxicity
Serum cholinesterase
Potential biomarker
Mice
Hepatotoxicity induced by radix Sophorae tonkinensis in mice and increased serum cholinesterase as a potential supplemental biomarker for liver injury
期刊论文
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2017, 卷号: 69, 页码: 193-202
作者:
Wang Liping[1]
;
Lu Jinyao[2]
;
Sun Wei[3]
;
Gu Yingmin[4]
;
Zhang Chaochao[5]
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/04/26
Hepatotoxicity
Mice
Potential biomarker
Radix Sophorae tonkinensis
Serum cholinesterase
Intersubunit physical couplings fostered by the left flipper domain facilitate channel opening of P2X4 receptors
期刊论文
Journal of Biological Chemistry, 2017, 卷号: 292, 期号: 18, 页码: 7619-7635
作者:
Wang, Jin
;
Sun, Liang-Fei
;
Cui, Wen-Wen
;
Zhao, Wen-Shan
;
Ma, Xue-Fei
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/23
*P2X receptors
*conformational change
*gating
*ion channel
*molecular simulations
*physical couplings
*protein domain
*receptor structure-function
*single channel recording
Exploration of the Peptide Recognition of an Amiloride-sensitive FMRFamide Peptide-gated Sodium Channel
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2016, 卷号: 291, 期号: 14
作者:
Niu, You-Ya
;
Yang, Yang
;
Liu, Yan
;
Huang, Li-Dong
;
Yang, Xiao-Na
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
A Highly Conserved Salt Bridge Stabilizes the Kinked Conformation of 2,3-Sheet Essential for Channel Function of P2X4 Receptors
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2016, 卷号: 291, 期号: 15
作者:
Zhao, Wen-Shan
;
Sun, Meng-Yang
;
Sun, Liang-Fei
;
Liu, Yan
;
Yang, Yang
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
ATP
conformational change
ion channel
protein expression
protein stability
P2X receptors
salt bridge
Decorin alleviated chronic hydrocephalus via inhibiting TGF-β1/Smad/CTGF pathway after subarachnoid hemorrhage in rats
期刊论文
Brain Research, 2016, 卷号: 1630, 页码: 241-253
作者:
Yan, Hui
;
Chen, Yujie
;
Li, Lingyong
;
Jiang, Jiaode
;
Wu, Guangyong
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/03
Connective tissue growth factor
Decorin
Hydrocephalus
Subarachnoid fibrosis
Subarachnoid hemorrhage
Transforming growth factor-beta1
A highly conserved salt bridge stabilizes the kinked conformation of β2,3-sheet essential for channel function of P2X4 receptors
期刊论文
Journal of Biological Chemistry, 2016, 卷号: 291, 期号: 15, 页码: 7990-8003
作者:
Zhao, Wen-Shan
;
Sun, Meng-Yang
;
Sun, Liang-Fei
;
Liu, Yan
;
Yang, Yang
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/23
ATP
P2X receptors
conformational change
ion channel
protein expression
protein stability
salt bridge
Exploration of the peptide recognition of an amiloridesensitive fmrfamide peptide-gated sodium channel
期刊论文
Journal of Biological Chemistry, 2016, 卷号: 291, 期号: 14, 页码: 7571-7582
作者:
Niu, You-Ya
;
Yang, Yang
;
Liu, Yan
;
Huang, Li-Dong
;
Yang, Xiao-Na
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/23
FMRFamide (Phe-Met-Arg-Phe-NH2) peptides
FaNaC channels
channel gating
epithelial sodium channel (ENaC)
ion channel
ligand-binding protein
ligand-recognition
neuropeptide
peptide interaction
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