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浏览/检索结果: 共8条，第1-8条 帮助 已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Effects of Absence of Constitutive Androstane Receptor on Bile Acid Homeostasis in Male and Female Mice. 期刊论文 Toxicological Sciences, 2019, 卷号: Vol.171 No.1, 页码: 132-145 作者:  Lickteig, Andrew J;  Zhang, Youcai;  Klaassen, Curtis D;  Csanaky, Ivá;  n L 收藏  |  浏览/下载：12/0  |  提交时间：2019/11/21 bile acids  biliary excretion  constitutive androstane receptor  muricholic acid  taurocholic acid   Dose-response effect of berberine on bile acid profile and gut microbiota in mice 期刊论文 BMC Complementary and Alternative Medicine, 2016, 卷号: 16, 期号: 1, 页码: 394 作者:  Guo, Ying;  Zhang, YouCai;  Huang, WeiHua;  Selwyn, Felcy Pavithra;  Klaassen, Curtis D.* 收藏  |  浏览/下载：6/0  |  提交时间：2019/12/03 Berberine  Bile acids  Gut Microbiota  Mice   Role of CYP3A in Isoniazid Metabolism In Vivo 期刊论文 DRUG METABOLISM AND PHARMACOKINETICS, 2014, 卷号: 29, 期号: 2, 页码: 219-222 作者:  Liu, Ke;  Li, Feng;  Lu, Jie;  Gao, Zhiwei;  Klaassen, Curtis D. 收藏  |  浏览/下载：15/0  |  提交时间：2019/01/08 isoniazid  metabolism  cytochrome P450 3A  hepatotoxicity  mice   Nrf2 protects against furosemide-induced hepatotoxicity 期刊论文 Toxicology, 2014, 卷号: 324, 页码: 35-42 作者:  Qu, Qiang;  Liu, Jie;  Zhou, Hong-Hao;  Klaassen, Curtis D 收藏  |  浏览/下载：52/0  |  提交时间：2019/12/03 ARE  antioxidant responsive element  Bax  BCL2-associated X protein  Chop10 or Gadd153  C/Ebp-homologous protein  Egr1  early growth response factor  Gadd45  growth arrest and DNA-damage-inducible protein  Gclm  glutamate–cysteine ligase modifier subunit  Gclc  glutamate–cysteine ligase catalytic subunit  Ho-1  hemeoxygenase-1  IL-1β  interleukin 1 beta  Keap1  Kelch-like ECH-associated protein 1  MIP-2  macrophage inflammatory protein 2  mKC  mouse keratinocyte-derived chemokine  MT-1  metallothionein-1  Nqo1  NAD(P)H quinone oxidoreductase 1  Nrf2  nuclear factor E2-related factor-2  P450  cytochrome P450  STIM1  stromal interaction molecule 1  MAFG  v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G  Furosemide  Nrf2  Hepatotoxicity  ER stress  Oxidative stress  Inflammation   Repeated administration of berberine inhibits cytochromes P450 in humans 期刊论文 European Journal of Clinical Pharmacology, 2012, 卷号: 68, 期号: 2, 页码: 213-217 作者:  Guo, Ying;  Chen, Yao;  Tan, Zhi-rong;  Klaassen, Curtis D.;  Zhou, Hong-hao* 收藏  |  浏览/下载：6/0  |  提交时间：2019/12/03 Berberine  CYP2D6  CYP2C9  CYP3A4  Humans   Diurnal Variation of Hepatic Antioxidant Gene Expression in Mice 期刊论文 2012, 卷号: 7, 期号: 8 作者:  Xu, Yi-Qiao[1];  Zhang, Dan[1];  Jin, Tao[1];  Cai, Ding-Jun[2];  Wu, Qin[1] 收藏  |  浏览/下载：5/0  |  提交时间：2019/12/06 CYP2D plays a major role in berberine metabolism in liver of mice and humans 期刊论文 Xenobiotica, the fate of foreign compounds in biological systems, 2011, 卷号: 41, 期号: 11, 页码: 996-1005 作者:  Guo, Ying;  Li, Feng;  Ma, Xiaochao;  Cheng, Xingguo;  Zhou, Honghao* 收藏  |  浏览/下载：3/0  |  提交时间：2019/12/03 Berberine  liver  metabolism  mice  humans   Dose-response of berberine on hepatic cytochromes P450 mRNA expression and activities in mice 期刊论文 Journal of Ethnopharmacology, 2011, 卷号: 138, 期号: 1, 页码: 111-118 作者:  Guo, Ying;  Pope, Chad;  Cheng, Xingguo;  Zhou, Honghao*;  Klaassen, Curtis D. 收藏  |  浏览/下载：4/0  |  提交时间：2019/12/03 Berberine  Liver  Drug–drug interactions  AhR  aryl hydrocarbon receptor  CAR  constitutive androstane receptor  CYP  Cytochrome P450  Gapdh  glyceraldehyde-3-phosphate dehydrogenase  HLM  human liver microsomes  HNF  hepatocyte nuclear factor  HPLC–MS  high-performance liquid chromatography–tandem mass spectrometry  MDR1a  multi-drug-resistance 1a  MLm  mouse liver microsomes  PPARα  peroxisome proliferator-activated receptor alpha  PXR  pregnane X receptor  RT-PCR  reverse transcription-quantitative polymerase chain reaction