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中国水产科学院 [36]
上海药物研究所 [7]
兰州大学 [4]
武汉轻工大学 [2]
大连理工大学 [1]
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期刊论文 [54]
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Drug target inference by mining transcriptional data using a novel graph convolutional network framework
期刊论文
PROTEIN & CELL, 2021, 页码: 21
作者:
Zhong, Feisheng
;
Wu, Xiaolong
;
Yang, Ruirui
;
Li, Xutong
;
Wang, Dingyan
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/12/01
drug target inference
transcriptomics
deep learning
experimental verification
Deep Learning Enhancing Kinome-Wide Polypharmacology Profiling: Model Construction and Experiment Validation
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 16, 页码: 8723-8737
作者:
Li, Xutong
;
Li, Zhaojun
;
Wu, Xiaolong
;
Xiong, Zhaoping
;
Yang, Tianbiao
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/12/21
Deep Learning Enhancing Kinome-Wide Polypharmacology Profiling: Model Construction and Experiment Validation
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 16, 页码: 8723-8737
作者:
Li, Xutong
;
Li, Zhaojun
;
Wu, Xiaolong
;
Xiong, Zhaoping
;
Yang, Tianbiao
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/12/21
Optimizing chemical reaction conditions using deep learning: a case study for the Suzuki-Miyaura cross-coupling reaction
期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2020, 卷号: 7, 期号: 16, 页码: 2269-2277
作者:
Fu, Zunyun
;
Li, Xutong
;
Wang, Zhaohui
;
Li, Zhaojun
;
Liu, Xiaohong
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2020/12/24
KinomeX: a web application for predicting kinome-wide polypharmacology effect of small molecules
期刊论文
BIOINFORMATICS, 2019, 卷号: 35, 期号: 24, 页码: 5354-5356
作者:
Li, Zhaojun
;
Li, Xutong
;
Liu, Xiaohong
;
Fu, Zunyun
;
Xiong, Zhaoping
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  |  
浏览/下载:79/0
  |  
提交时间:2020/07/01
Cajanine promotes osteogenic differentiation and proliferation of human bone marrow mesenchymal stem cells
期刊论文
ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE, 2019, 卷号: 28, 期号: 1
作者:
Zhang, Xiaozhe
;
Fu, Lingling
;
Jiao, Yong
;
Yu, Xing
;
Xu, Lin
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/12/05
mesenchymal stem cells
placenta
Cajanus cajan L.
tissue engineering
Accelerated Metabolite Levels of Aerobic Glycolysis and the Pentose Phosphate Pathway Are Required for Efficient Replication of Infectious Spleen and Kidney Necrosis Virus in Chinese Perch Brain Cells
期刊论文
BIOMOLECULES, 2019, 卷号: 9, 期号: 9
作者:
Guo, Xixi[1]
;
Wu, Shiwei[2]
;
Li, Ningqiu[3]
;
Lin, Qiang[4]
;
Liu, Lihui[5]
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2020/01/02
ISKNV
Siniperca chuatsi
glucose metabolism reprogramming
aerobic glycolysis
pentose phosphate pathway (PPP)
TCA cycle
Non-Targeted UHPLC-Q-TOF/MS-Based Metabolomics Reveals a Metabolic Shift from Glucose to Glutamine in CPB Cells during ISKNV Infection Cycle
期刊论文
METABOLITES, 2019, 卷号: 9, 期号: 9
作者:
Fu, Xiaozhe[1]
;
Guo, Xixi[2]
;
Wu, Shiwei[3]
;
Lin, Qiang[4]
;
Liu, Lihui[5]
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/01/02
ISKNV
metabolomics profile
differential metabolites
glucose metabolism
glutamine metabolism
First report of megalocytivirus (iridoviridae) in cultured bluegill sunfish, Lepomis macrochirus, in China
期刊论文
MICROBIAL PATHOGENESIS, 2019, 卷号: 135
作者:
Liu, Lihui[1]
;
Yu, Lujun[2]
;
Fu, Xiaozhe[3]
;
Lin, Qiang[4]
;
Liang, Hongru[5]
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/01/02
Bluegill sunfish
Propagation
Histopathology
ISKNV
Megalocytivirus
Chitosan and anisodamine improve the immune efficacy of inactivated infectious spleen and kidney necrosis virus vaccine in Siniperca chuatsi
期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2019, 卷号: 89, 页码: 52-60
作者:
Zhang, Jiacheng[1]
;
Fu, Xiaozhe[2]
;
Zhang, Yanqi[3]
;
Zhu, Wentao[4]
;
Zhou, Yong[5]
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/01/02
Siniperca chuatsi
ISKNV
Chitosan
poly(I:C)
Anisodamine
ims1312
Adjuvant
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