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中南大学 [6]
湖南中医药大学 [3]
衡阳师范学院 [2]
北京大学 [1]
武汉大学 [1]
内容类型
期刊论文 [13]
发表日期
2019 [4]
2016 [3]
2015 [1]
2014 [1]
2013 [3]
2006 [1]
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Mitogen-activated protein kinase signaling mediates opioid-induced presynaptic NMDA receptor activation and analgesic tolerance
期刊论文
JOURNAL OF NEUROCHEMISTRY, 2019, 卷号: 148, 期号: 2
作者:
Deng, Meichun
;
Chen, Shao-Rui
;
Chen, Hong
;
Luo, Yi
;
Dong, Yingchun
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/05
G protein-coupled receptor
NMDA receptor
opioid tolerance
primary afferent nerves
synaptic plasticity
mu-opioid receptor
Anti-parasitic effect on Toxoplasma gondii induced by a spider peptide lycosin-I
期刊论文
Experimental Parasitology, 2019, 卷号: 198, 页码: 17-25
作者:
Tang, Yaqin
;
Hou, Shengjie
;
Li, Xianyao
;
Wu, Mengqi
;
Ma, Binbin
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/24
Anti-parasitic
Invasion
Lycosin-I
Proliferation
Spider peptide
Toxoplasma gondii
Anti-Toxoplasma gondii effect of two spider venoms in vitro and in vivo
期刊论文
Toxicon : official journal of the International Society on Toxinology, 2019, 卷号: 166, 页码: 9-14
作者:
Hou, Shengjie
;
Liu, Yuan
;
Tang, Yaqin
;
Wu, Mengqi
;
Guan, Jianwu
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/24
Anti- Toxoplasma gondii
Invasion
Proliferation
Spider venom
Toxoplasma gondii
Spider venom peptides as potential drug candidates due to their anticancer and antinociceptive activities
期刊论文
JOURNAL OF VENOMOUS ANIMALS AND TOXINS INCLUDING TROPICAL DISEASES, 2019, 卷号: 25, 页码: -
作者:
Wu, Ting
;
Wang, Meng
;
Wu, Wenfang
;
Luo, Qianxuan
;
Jiang, Liping
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/27
spider venom peptides
antitumor
pain
drug candidates
Molecular determinant for the tarantula toxin Jingzhaotoxin-I slowing the fast inactivation of voltage-gated sodium channels
期刊论文
Toxicon, 2016, 卷号: 111, 期号: Volume 111, 页码: 13-21
作者:
Tao, Huai*
;
Chen, Xia
;
Lu, Min
;
Wu, Yuanyuan
;
Deng, Meichun
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/03
Jingzhaotoxin-I
Voltage-gated sodium channels
Inactivation
Mutation
JZTX
Jingzhaotoxin
VGSCs
voltage-gated sodium channels
TTX
tetrodotoxin
ICK
inhibitor cystine knot
RP-HPLC
reverse-phase high pressure liquid chromatography
MALDI-TOF
matrix assisted laser desorption/ionization time-of-flight
IC50
half-maximal inhibitory concentration
WT
wide type
Interaction site for the inhibition of tarantula Jingzhaotoxin-XI on voltage-gated potassium channel Kv2.1
期刊论文
Toxicon, 2016, 卷号: 124, 页码: 8-14
作者:
Tao, Huai*(陶怀)
;
Chen, Xia
;
Deng, Meichun
;
Xiao, Yucheng
;
Wu, Yuanyuan
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/27
Jingzhaotoxin-XI
Kv2.1
Mutation
Molecular determinant
JZTX-XI
Jingzhaotoxin-XI
HPLC
ion-exchange high-pressure liquid chromatography
RP-HPLC
reverse-phase HPLC
MALDI-TOF
matrix assisted laser desorption/ionization time-of-flight
WT
Wide Type
IC50
median inhibitory concentration
Molecular determinant for the tarantula toxin Jingzhaotoxin-I slowing the fast inactivation of voltage-gated sodium channels
期刊论文
Toxicon, 2016, 卷号: 111, 期号: Volume 111, 页码: 13-21
作者:
Tao, Huai*(陶怀)
;
Chen, Xia
;
Lu, Min
;
Wu, Yuanyuan
;
Deng, Meichun
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/27
Jingzhaotoxin-I
Voltage-gated sodium channels
Inactivation
Mutation
JZTX
Jingzhaotoxin
VGSCs
voltage-gated sodium channels
TTX
tetrodotoxin
ICK
inhibitor cystine knot
RP-HPLC
reverse-phase high pressure liquid chromatography
MALDI-TOF
matrix assisted laser desorption/ionization time-of-flight
IC50
half-maximal inhibitory concentration
WT
wide type
Inhibition of non-small cell lung cancer (NSCLC) growth by a novel small molecular inhibitor of EGFR
期刊论文
Oncotarget, 2015, 卷号: 6, 期号: 9, 页码: 6749-6761
作者:
Li, Jinsong
;
Deng, Huayun
;
Hu, Meichun
;
Fang, Yuanzhang
;
Vaughn, Amanda
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/03
EGFR
NSCLC
TKIs
tumor growth
Huwentoxin-XVI, an analgesic, highly reversible mammalian N-type calcium channel antagonist from Chinese tarantula Ornithoctonus huwena
期刊论文
Neuropharmacology, 2014, 卷号: 79, 页码: 657-667
作者:
Deng, Meichun*
;
Luo, Xuan
;
Xiao, Yucheng
;
Sun, Zhenghua
;
Jiang, Liping
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/12/03
HWTX-XVI
Tarantula toxin
N-type calcium channels
Dorsal root ganglia
Rat vas deferens
Pain model
Analgesic action
HWTX
Huwentoxin
ICK
inhibitor cystine knot
Cav channel
voltage-gated calcium channel
Nav channel
voltage-gated sodium channel
DRG
dorsal root ganglion
TTX
tetrodotoxin
TTX-R
TTX-resistant
TTX-S
TTX-sensitive
IC50
median inhibitory concentration
Kv channel
voltage-gated potassium channel
HPLC
high pressure liquid chromatography
MALDI-TOF
matrix assisted laser desorption/ionization time-of-flight
Synthesis and biological characterization of synthetic analogs of Huwentoxin-IV (Mu-theraphotoxin-Hh2a), a neuronal tetrodotoxin-sensitive sodium channel inhibitor
期刊论文
Toxicon, 2013, 卷号: 71, 页码: 57-65
作者:
Deng, Meichun*
;
Luo, Xuan
;
Jiang, Liping
;
Chen, Hanchun
;
Wang, Jun
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/03
DRG
Dorsal root ganglion
HPLC
HWTX
HWTX-IV
High pressure liquid chromatography
Huwentoxin
IC(50)
ICK
Inhibitor cystine knot
Kv channel
MALDI-TOF
Matrix assisted laser desorption/ionization time-of-flight
Median inhibitory concentration
Mutant
Patch-clamp
Protein folding
Solid-phase peptide synthesis
TTX
TTX-R
TTX-S
TTX-resistant
TTX-sensitive
Tetrodotoxin
VGSC
Voltage-gated potassium channel
Voltage-gated sodium channel
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