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CORC

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Follow on-based optimization of the biphenyl-DAPYs as HIV-1 nonnucleoside reverse transcriptase inhibitors against the wild-type and mutant strains 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 89
作者:  Zhuang, Chunlin;  Sang, Yali;  Pannecouque, Christophe;  Han, Sheng;  Han, Shuwen
收藏  |  浏览/下载：25/0  |  提交时间：2019/12/05
Synthesis and biological evaluation of dihydroquinazoline-2-amines as potent non-nucleoside reverse transcriptase inhibitors of wild-type and mutant HIV-1 strains 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 176
作者:  Jin, KaiJun;  Sang, YaLi;  Han, Sheng;  De Clercq, Erik;  Pannecouque, Christophe
收藏  |  浏览/下载：25/0  |  提交时间：2019/12/05
Design, synthesis and biological evaluation of novel acetamide-substituted doravirine and its prodrugs as potent HIV-1 NNRTIs 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 3, 页码: 447-456
作者:  Wang, Zhao;  Yu, Zhao;  Kang, Dongwei;  Zhang, Jian;  Tian, Ye
收藏  |  浏览/下载：5/0  |  提交时间：2019/12/11
Targeting the hydrophobic channel of NNIBP: discovery of novel 1,2,3-triazole-derived diarylpyrimidines as novel HIV-1 NNRTIs with high potency against wild-type and K103N mutant virus 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2019, 卷号: 17, 期号: 12, 页码: 3202-3217
作者:  Zhou, Zhongxia;  Liu, Tao;  Wu, Gaochan;  Kang, Dongwei;  Fu, Zhipeng
收藏  |  浏览/下载：11/0  |  提交时间：2019/12/11
Molecular design opportunities presented by solvent-exposed regions of target proteins 期刊论文
MEDICINAL RESEARCH REVIEWS, 2019, 卷号: 39, 期号: 6, 页码: 2194-2238
作者:  Jiang, Xiangyi;  Yu, Ji;  Zhou, Zhongxia;  Kongsted, Jacob;  Song, Yuning
收藏  |  浏览/下载：8/0  |  提交时间：2019/12/11
Design, synthesis and biological evaluation of 3-hydroxyquinazoline-2,4(1H, 3H)-diones as dual inhibitors of HIV-1 reverse transcriptase-associated RNase H and integrase 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 17, 页码: 3836-3845
作者:  Gao, Ping;  Cheng, Xiqiang;  Sun, Lin;  Song, Shu;  Alvarez, Mar
收藏  |  浏览/下载：4/0  |  提交时间：2019/12/11
Identification of Dihydrofuro[3,4-d]pyrimidine Derivatives as Novel HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors with Promising Antiviral Activities and Desirable Physicochemical Properties. 期刊论文
Journal of medicinal chemistry, 2019
作者:  Kang Dongwei;  Zhang Heng;  Wang Zhao;  Zhao Tong;  Ginex Tiziana
收藏  |  浏览/下载：15/0  |  提交时间：2019/12/13
Identification of Dihydrofuro[3,4-d]pyrimidine Derivatives as Novel HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors with Promising Antiviral Activities and Desirable Physicochemical Properties 期刊论文
Journal of Medicinal Chemistry, 2019, 卷号: Vol.62 No.3, 页码: 1484-1501
作者:  Dongwei Kang;  Heng Zhang;  Zhao Wang;  Tong Zhao;  Tiziana Ginex
收藏  |  浏览/下载：5/0  |  提交时间：2019/12/17
Discovery of biphenyl-substituted diarylpyrimidines as non-nucleoside reverse transcriptase inhibitors with high potency against wild-type and mutant HIV-1 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 145
作者:  Jin, KaiJun;  Yin, Hong;  De Clercq, Erik;  Pannecouque, Christophe;  Meng, Ge
收藏  |  浏览/下载：2/0  |  提交时间：2019/12/05
Design and synthesis of a novel series of non-nucleoside HIV-1 inhibitors bearing pyrimidine and N-substituted aromatic piperazine 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 22
作者:  Jin, KaiJun;  Sang, YaLi;  De Clercq, Erik;  Pannecouque, Christophe;  Meng, Ge
收藏  |  浏览/下载：11/0  |  提交时间：2019/12/05

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