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上海药物研究所 [3]
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期刊论文 [24]
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Characteristics and causes of a catastrophic snow avalanche that occurred on January 17, 2023, in Tibet
期刊论文
LANDSLIDES, 2024, 页码: 7
作者:
Chen, Ningsheng
;
Li, Anhui
;
Tian, Shufeng
;
Rahman, Mahfuzur
;
Huang, Na
收藏
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浏览/下载:0/0
  |  
提交时间:2024/03/25
无
Sugemalimab versus placebo after concurrent or sequential chemoradiotherapy in patients with locally advanced, unresectable, stage III non-small-cell lung cancer in China (GEMSTONE-301): interim results of a randomised, double-blind, multicentre, phase 3 trial
期刊论文
LANCET ONCOLOGY, 2022, 卷号: 23
作者:
Zhou, Qing
;
Chen, Ming
;
Jiang, Ou
;
Pan, Yi
;
Hu, Desheng
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  |  
浏览/下载:104/0
  |  
提交时间:2022/03/21
Structure-based design, synthesis and bioactivity evaluation of macrocyclic inhibitors of mutant isocitrate dehydrogenase 2 (IDH2) displaying activity in acute myeloid leukemia cells
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 203, 页码: 19
作者:
Che, Jinxin
;
Huang, Feng
;
Zhang, Mengmeng
;
Xu, Gaoya
;
Qu, Bingxue
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  |  
浏览/下载:21/0
  |  
提交时间:2020/12/21
Metabolic pathways
Isocitrate dehydrogenase 2
Conformational restriction
Macrocyclic derivatives
Inhibitors
Structure-based design, synthesis and bioactivity evaluation of macrocyclic inhibitors of mutant isocitrate dehydrogenase 2 (IDH2) displaying activity in acute myeloid leukemia cells
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 203, 页码: 19
作者:
Che, Jinxin
;
Huang, Feng
;
Zhang, Mengmeng
;
Xu, Gaoya
;
Qu, Bingxue
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/12/21
Metabolic pathways
Isocitrate dehydrogenase 2
Conformational restriction
Macrocyclic derivatives
Inhibitors
Exposure to 2,3,3 ',4,4 ',5-hexachlorobiphenyl promotes nonalcoholic fatty liver disease development in C57BL/6 mice
期刊论文
ENVIRONMENTAL POLLUTION, 2020, 卷号: 263, 页码: 1-10
作者:
Shan, Qiuli
;
Chen, Ningning
;
Liu, Wei
;
Qu, Fan
;
Chen, Anhui
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  |  
浏览/下载:80/0
  |  
提交时间:2021/09/14
NAFLD
PCB 156
Transcriptomics
Lipid accumulation
Oxidative stress
Exposure to 2,3,3 ',4,4 ',5-hexachlorobiphenyl promotes nonalcoholic fatty liver disease development in C57BL/6 mice
期刊论文
ENVIRONMENTAL POLLUTION, 2020, 卷号: 263, 页码: 1-10
作者:
Shan, Qiuli
;
Chen, Ningning
;
Liu, Wei
;
Qu, Fan
;
Chen, Anhui
收藏
  |  
浏览/下载:69/0
  |  
提交时间:2021/09/14
NAFLD
PCB 156
Transcriptomics
Lipid accumulation
Oxidative stress
Discovery of novel indoleaminopyrimidine NIK inhibitors based on molecular docking-based support vector regression (SVR) model
期刊论文
CHEMICAL PHYSICS LETTERS, 2019, 卷号: 718, 页码: 38-45
作者:
Ye, Qing
;
Li, Qiu
;
Gao, Anhui
;
Ying, Huazhou
;
Cheng, Gang
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  |  
浏览/下载:6/0
  |  
提交时间:2020/07/01
Quantitative Lysine Reactivity Profiling Reveals Conformational Inhibition Dynamics and Potency of Aurora A Kinase Inhibitors
期刊论文
ANALYTICAL CHEMISTRY, 2019, 卷号: 91, 页码: 13222-13229
作者:
Chen, Jin
;
Wang, Anhui
;
Liu, Bing
;
Zhou, Ye
;
Luo, Pan
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/02
Discovery of Novel Indoleaminopyrimidine NIK Inhibitors based on Molecular Docking-based Support Vector Regression Model
期刊论文
Chemical Physics Letters, 2019
作者:
Qing Ye
;
Qiu Li
;
Anhui Gao
;
Huazhou Ying
;
Gang Cheng
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/12/13
Benzoxazinone-containing 3,5-dimethylisoxazole derivatives as BET bromodomain inhibitors for treatment of castration-resistant prostate cancer
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 152, 页码: 542-559
作者:
Xue, Xiaoqian
;
Zhang, Yan
;
Wang, Chao
;
Zhang, Maofeng
;
Xiang, Qiuping
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/02
BRD4
Prostate cancer
Bromodomain inhibitor
3,5-Dimethylisoxazole
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