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"One-Pot" Synthesis of Molnupiravir from Cytidine 期刊论文
ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2022, 卷号: 26, 期号: 2, 页码: 358-364
作者:  Hu, TW (Hu, Tianwen) [1] , [2];  Xie, YC (Xie, Yuanchao) [3];  Zhu, FQ (Zhu, Fuqiang) [4];  Gong, XD (Gong, Xudong) [4];  Liu, Y (Liu, Yin) [2] , [3]
收藏  |  浏览/下载:126/0  |  提交时间:2022/03/23
Design, synthesis, in vitro evaluation of a new pyrrolo[1,2-a]thiazolo[5,4-d]pyrimidinone derivatives as cholinesterase inhibitors against Alzheimer's disease 期刊论文
JOURNAL OF HETEROCYCLIC CHEMISTRY, 2022, 卷号: 59, 期号: 6, 页码: 1086-1101
作者:  Zeng, Y (Zeng, Yan) [1] , [2];  Nie, LF (Nie, Lifei) [1];  Liu, L (Liu, Liu) [1];  Niu, C (Niu, Chao) [1] , [2];  Li, Y (Li, Yi) [1] , [2]
收藏  |  浏览/下载:21/0  |  提交时间:2022/06/21
Facile and Cost-Effective Route for the Synthesis of Simmerafil 期刊论文
ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2021, 卷号: 25, 期号: 11, 页码: 2432-2437
作者:  Odilov, Abdullajon;  Liu, Yin;  Hu, Tianwen;  Jiang, Xiangrui;  Suo, Jin
收藏  |  浏览/下载:20/0  |  提交时间:2022/01/18
Identification of pyrogallol as a warhead in design of covalent inhibitors for the SARS-CoV-2 3CL protease 期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 12
作者:  Su, Haixia;  Yao, Sheng;  Zhao, Wenfeng;  Zhang, Yumin;  Liu, Jia
收藏  |  浏览/下载:30/0  |  提交时间:2021/08/17
SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target 期刊论文
CELL RESEARCH, 2021, 页码: 14
作者:  Xia, Bingqing;  Shen, Xurui;  He, Yang;  Pan, Xiaoyan;  Liu, Feng-Liang
收藏  |  浏览/下载:78/0  |  提交时间:2021/08/17
Challenges and stepwise fit-for-purpose optimization for bioanalyses of remdesivir metabolites nucleotide monophosphate and triphosphate in mouse tissues using LC-MS/MS 期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 194, 页码: 10
作者:  Hu, Wenjuan;  Chang, Lu;  Ke, Changqiang;  Xie, Yuanchao;  Shen, Jingshan
收藏  |  浏览/下载:28/0  |  提交时间:2021/05/24
The novel small-molecule TPN10456 inhibits Th17 cell differentiation and protects against experimental autoimmune encephalomyelitis 期刊论文
CELLULAR & MOLECULAR IMMUNOLOGY, 2020, 页码: 4
作者:  Yang, Cuixia;  Lv, Jie;  Jiang, Xiangrui;  Xiang, Zhenglong;  Gong, Ran
收藏  |  浏览/下载:22/0  |  提交时间:2020/12/24
Automated design and optimization of multitarget schizophrenia drug candidates by deep learning 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 204, 页码: 16
作者:  Tan, Xiaoqin;  Jiang, Xiangrui;  He, Yang;  Zhong, Feisheng;  Li, Xutong
收藏  |  浏览/下载:36/0  |  提交时间:2020/12/21
Synthesis and biological investigation of triazolopyridinone derivatives as potential multireceptor atypical antipsychotics 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 8, 页码: 6
作者:  Shi, Wenqiang;  Wang, Yu;  Wu, Chunhui;  Yang, Feipu;  Zheng, Wei
收藏  |  浏览/下载:26/0  |  提交时间:2020/07/01
Metal-free quinolylation of the primary amino groups of amino acid derivatives and peptides with dihydrooxazolo[3,2-a]quinoliniums 期刊论文
GREEN CHEMISTRY, 2019, 卷号: 21, 期号: 15, 页码: 4231-4237
作者:  Liu, Peng;  Li, Bo;  Xi, Mengyu;  Chen, Zhaoqiang;  Sun, Haiguo
收藏  |  浏览/下载:9/0  |  提交时间:2020/07/01


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