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科研机构
山东大学 [3]
西安交通大学 [2]
上海药物研究所 [2]
暨南大学 [2]
武汉大学 [2]
中国医学科学院 北京... [2]
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期刊论文 [24]
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2021 [1]
2020 [1]
2019 [8]
2018 [2]
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Discovery of a novel, potent and selective small-molecule inhibitor of PD-1/PD-L1 interaction with robust in vivo anti-tumour efficacy
期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2021, 页码: 20
作者:
Liu, Chenglong
;
Zhou, Feilong
;
Yan, Ziqin
;
Shen, Lian
;
Zhang, Xichen
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/06/11
immunotherapy
PD-1/PD-L1
TGF-beta
tumour immune microenvironment
Therapeutic vaccination against leukaemia via the sustained release of co-encapsulated anti-PD-1 and a leukaemia-associated antigen
期刊论文
NATURE BIOMEDICAL ENGINEERING, 2020, 页码: 19
作者:
Xie, Xiaoling
;
Hu, Yuxing
;
Ye, Tong
;
Chen, Yiran
;
Zhou, Lijuan
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2021/03/29
NLG919/cyclodextrin complexation and anti-cancer therapeutic benefit as a potential immunotherapy in combination with paclitaxel
期刊论文
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2019, 卷号: 138, 页码: 8
作者:
Xu, Jian
;
Ren, Xiaohong
;
Guo, Tao
;
Sun, Xian
;
Chen, Xiaojin
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2020/07/01
Cyclodextrins
NLG919
Solubility enhancement
Paclitaxel
IDO-1 combination immunochemotherapy
Prim-O-glucosylcimifugin enhances the antitumour effect of PD-1 inhibition by targeting myeloid-derived suppressor cells
期刊论文
JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2019, 卷号: 7, 期号: 1, 页码: 15
作者:
Gao, Wanfeng
;
Zhang, Xiaoyun
;
Yang, Wendong
;
Dou, Daolei
;
Zhang, Heng
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2020/01/10
Prim-O-glucosylcimifugin
Myeloid-derived suppressor cells
Proliferation
Metabolism
PD-1 inhibitor
Checkpoint blockade and nanosonosensitizer- augmented noninvasive sonodynamic therapy combination reduces tumour growth and metastases in mice
期刊论文
NATURE COMMUNICATIONS, 2019, 卷号: 10
作者:
Yue, Wenwen
;
Chen, Liang
;
Yu, Luodan
;
Zhou, Bangguo
;
Yin, Haohao
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  |  
浏览/下载:75/0
  |  
提交时间:2019/12/26
Challenges and potential of PD-1/PD-L1 checkpoint blockade immunotherapy for glioblastoma
期刊论文
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2019, 卷号: 38
作者:
Wang, Xin
;
Guo, Gaochao
;
Guan, Hui
;
Yu, Yang
;
Lu, Jie
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/12/05
Glioblastoma multiforme
Nivolumab
Tumour infiltrating lymphocytes
Tumour mutation load
Temozolomide
Challenges and potential of PD-1/PD-L1 checkpoint blockade immunotherapy for glioblastoma 11 Medical and Health Sciences 1112 Oncology and Carcinogenesis
期刊论文
Journal of Experimental and Clinical Cancer Research, 2019, 卷号: 38, 期号: 1
作者:
Wang X.
;
Guo G.
;
Guan H.
;
Yu Y.
;
Lu J.
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/11
Glioblastoma multiforme
Nivolumab
Temozolomide
Tumour infiltrating lymphocytes
Tumour mutation load
Challenges and potential of PD-1/PD-L1 checkpoint blockade immunotherapy for glioblastoma
期刊论文
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2019, 卷号: 38
作者:
Wang, Xin
;
Guo, Gaochao
;
Guan, Hui
;
Yu, Yang
;
Lu, Jie
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/12/11
Glioblastoma multiforme
Nivolumab
Tumour infiltrating lymphocytes
Tumour mutation load
Temozolomide
Tumour-associated macrophages-derived CXCL8 determines immune evasion through autonomous PD-L1 expression in gastric cancer.
期刊论文
Gut, 2019
作者:
Chao Lin
;
Hongyong He
;
Hao Liu
;
Ruochen Li
;
Yifan Chen
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/13
gastric
cancer
immunotherapy
macrophages
Development of small-molecule immune checkpoint inhibitors of PD-1/PD-L1 as a new therapeutic strategy for tumour immunotherapy
期刊论文
2019, 卷号: 27, 期号: 3, 页码: 244-256
作者:
Li, Kui
;
Tian, Hongqi
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/01/03
Small-molecule inhibitors
PD-1
PD-L1 immune checkpoint
targeted therapy
tumour immunotherapy
clinical and preclinical research
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