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上海药物研究所 [2]
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期刊论文 [12]
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Acetaldehyde induces similar cytotoxic and genotoxic risks in BEAS-2B cells and HHSteCs: involvement of differential regulation of MAPK/ERK and PI3K/AKT pathways
期刊论文
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 2023, 卷号: 30
作者:
Zhang, Jingni
;
Wang, Hongjuan
;
Chen, Huan
;
Liu, Yong
;
Wang, An
收藏
  |  
浏览/下载:150/0
  |  
提交时间:2023/11/17
Acetaldehyde
Cytotoxicity
Genotoxicity
BEAS-2B cells
HHSteCs
MAPK/ERK
PI3K/AKT
Development of a nornicotine-reduced flue-cured tobacco line via EMS mutagenesis of nicotine N-demethylase genes
期刊论文
PLANT SIGNALING & BEHAVIOR, 2020, 卷号: 15, 期号: 2
作者:
Song, Zhongbang
;
Sui, Xueyi
;
Li, Meiyun
;
Gao, Yulong
;
Li, Wenzheng
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2022/03/01
Nornicotine
NNN
Nicotine demethylation
dCAPS marker
Tobacco
The inhibition of cytochrome P450 2A13-catalyzed NNK metabolism by NAT, NAB and nicotine
期刊论文
TOXICOLOGY RESEARCH, 2016, 卷号: 5, 期号: 4, 页码: 1115-1121
作者:
Liu, Xingyu
;
Zhang, Jie
;
Zhang, Chen
;
Yang, Bicheng
;
Wang, Limeng
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/06/20
The inhibition of cytochrome p450 2a13-catalyzed nnk metabolism by nat, nab and nicotine
期刊论文
Toxicology research, 2016, 卷号: 5, 期号: 4, 页码: 1115-1121
作者:
Liu, Xingyu
;
Zhang, Jie
;
Zhang, Chen
;
Yang, Bicheng
;
Wang, Limeng
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/05/09
Tobacco carcinogen NNK-induced lung cancer animal models and associated carcinogenic mechanisms
期刊论文
Acta Biochim Biophys Sin (Shanghai), 2015, 卷号: 47, 期号: 7, 页码: 477-487
作者:
Ge GZ[
;
Xu TR[*]
;
Chen CS[*]
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  |  
浏览/下载:14/0
  |  
提交时间:2015/09/10
NNK
animal model
lung cancer
oncogenic mechanisms
Acrolein- and 4-Aminobiphenyl-DNA adducts in human bladder mucosa and tumor tissue and their mutagenicity in human urothelial cells
期刊论文
ONCOTARGET, 2014, 卷号: 5, 期号: 11, 页码: 3526-3540
Lee, Hyun-Wook
;
Wang, Hsiang-Tsui
;
Weng, Mao-wen
;
Hu, Yu
;
Chen, Wei-sheng
;
Chou, David
;
Liu, Yan
;
Donin, Nicholas
;
Huang, William C.
;
Lepor, Herbert
;
Wu, Xue-Ru
;
Wang, Hailin
;
Beland, Frederick A.
;
Tang, Moon-shong
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2015/03/24
Bladder cancer
4-aminobiphenyl
Acrolein
DNA repair
Mutagenesis
Development, validation, and application of a liquid chromatography-tandem mass spectrometry method for the determination of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in human hair
期刊论文
analytical and bioanalytical chemistry, 2012, 卷号: 404, 期号: 8, 页码: 2259-2266
作者:
Yao, Li
;
Yang, Jun
;
Guan, Ya-feng
;
Liu, Bai-zhan
;
Zheng, Sai-jing
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2015/11/13
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol
Molecularly imprinted polymers
Solid-phase extraction
Dispersive liquid-liquid microextraction
Liquid chromatography tandem mass spectrometry
Human hair
The application of hepatic P450 reductase null gpt delta mice in studying the role of hepatic P450 in genotoxic carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced mutagenesis
期刊论文
ARCHIVES OF TOXICOLOGY, 2012, 卷号: 86, 期号: 11, 页码: 1753-1761
作者:
Luan, Yang
;
Xing, Guozhen
;
Qi, Xinming
;
Wu, Mengjun
;
Li, Chenggang
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
Hepatic P450
gpt delta mouse
Gene mutation assay, NNK
An Investigation of the Catalytic Activity of CYP2A13*4 with Coumarin and Polymorphisms of CYP2A13 in a Chinese Han Population
期刊论文
DRUG METABOLISM AND DISPOSITION, 2012, 卷号: 40, 期号: 5, 页码: 847-851
作者:
Liu, Ting
;
Hong, Yanjun
;
Li, Zhaohui
;
Hong, Junyan
;
Zeng, Su
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/01/08
Association of human aryl hydrocarbon receptor gene polymorphisms with risk of lung cancer among cigarette smokers in a Chinese population
期刊论文
PHARMACOGENETICS AND GENOMICS, 2009, 卷号: 19, 期号: 1
作者:
Chen, Dan
;
Tian, Tian
;
Wang, Haifeng
;
Liu, Hongliang
;
Hu, Zhibin
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/19
AHR
genetic susceptibility
haplotype
lung cancer
molecular epidemiology
polymorphism
tobacco carcinogen
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