Alzheimer'sdisease  Microglia  AMPK alpha 1  DW14006  Phagocytosis  Neuro-inflammation  

scavenger receptor-like protein  C-type lectin domain  LPS-binding activity  bacterial clearance  phagocytosis activity  Scylla paramamosain  

apo  apolipoprotein  HDL  high-density lipoprotein  HNF-1α,4α  hepatocyte nuclear factor-1α,4α  LRH-1  liver receptor homolog-1  Foxa2  forkhead box A2  PAF  platelet activating factor  LXR  liver X receptor  RXR  retinoid X receptor  FXR  farnesoid X receptor  SHP  small heterodimer partner  S1P  Sphingosine-1-Phosphate  CVD  cardiovascular disease  HDL-C  HDL cholesterol  RCT  reverse cholesterol transport  MHC  major histocompatibility complex class III  TNF  tumor necrosis factor  HRP  haptoglobin-related protein  PON-I  paraoxonase-1  SNP  single nucleotide polymorphism  T1,2D  type 1,2 diabetes  RA  rheumatoid arthritis  ABCA1  ATP-binding cassette transporter A1  PPAR-γ  peroxisome proliferator-activated receptor γ  IL  interleukin  ABCG  ATP-binding cassette sub-family G  CETP  cholesteryl ester transfer protein  SR-B1  scavenger receptor class B member 1  MODY3  maturity-onset diabetes of the young type 3  MUP  major urinary protein  RBP  retinol binding protein  RAR  retinoic acid receptor  TR  thyroid hormone receptor  PI3K  phosphatidylinositol 3-kinase  DHC  dihydrocapsaicin  HRE  hormone response element  IGF-1  insulin-like growth factors  PAF-R  platelet activating factor receptor  TGF-α,β  transforming growth factor-α,β  EGF  epidermal growth factor  HGF  hepatic growth factor  VLDL  very low-density lipoprotein  LDL  low-density lipoprotein  ldlr  LDL receptor  ldlr−/−  LDL-receptor deficient  LCAT  lecithin-cholesterol acyltransferase  CE  cholesteryl ester  TC  total cholesterol  LDL-C  LDL cholesterol  VLDL-C  VLDL cholesterol  CHD  coronary heart disease  Mets  metabolic syndrome  S1PR  S1P receptor  NF-κB  nuclear factor-κB  NO  nitrogen oxide  eNOS  endothelial nitric oxide synthase  apoM-TgN mice  mice overexpressing human apoM by approximately two-fold  apoM-TgH mice  mice overexpressing human apoM by approximately ten-fold  apoM−/− mice  apoM-null mice  apoE−/−  apoE-null mice  Apolipoprotein M  Regulation  Function  

Chlamys farreri  Low-density lipoprotein receptor-related  protein (LRP)  Innate immunity  Ligands binding  Antimicrobial activity  

Psychological stress  Toll-like 4  NF-κB  Cytokines  Innate immune  Atherosclerosis  HPA  hypothalamic-pituitary-adrenal  SAM  sympathetic-adrenal-medullary  SNS  sympathetic nervous system  Th1, Th2  T helper cell type1, T helper cell type 2  NE  norepinephrine  CRF  corticotropin-releasing factor  POMC  proopiomelanocortin  ACTH  adrenocorticotropic hormone  α-MSH  alpha melanocyte-stimulating hormone  CNS  central nervous system  CRP  C-reactive protein  CD  cluster of differentiation  NK  natural killer  CMV  cytomegalovirus  HSV  herpes simplex virus  VZV  varicella zoster virus  IL-1, IL-4, IL-6, IL-8, IL-10  interleukin-1, interleukin-4, interleukin-6, interleukin-8, interleukin-10  NF-κB  nuclear factor-κB  PBMCs  peripheral blood monocytes  apoE−/− mice  apolipoprotein E knockout mice  LDL  low-density lipoprotein  TLRs, TLR4  Toll-like receptors, Toll-like receptor 4  PRRs  pattern-recognition receptors  SRs  scavenger receptors  oxLDL  oxidized low density lipoprotein  PAMPs  pathogen-associated molecular patterns  PNI  psychoneuroimmunology  GC  glucocorticoid  MR  mineraloreceptor  GR  glucocorticoid receptor  TNF-α  tumor necrosis factor-alpha  LPS  lipopolysaccharide  APPs  acute phase proteins  APR  acute phase response  HSP  heat shock protein  EDA  extra domain A  DAMPs  damage-associated molecular patterns  siRNA  small interfering RNA  MAPKs  mitogen activated protein kinases  MyD88  myeloid differentiation factor-88  TRIF  TIR domain-containing adapter protein inducing IFN-β  ACS  acute coronary syndrome  CHD  coronary heart disease  M-CSF  macrophage-colony-stimulating factor  ICAM-1  intercellular adhesion molecule-1  VCAM-1  vascular cell adhesion molecule-1  MMPs  matrix-degrading matrix metalloproteinases  β-AR  beta-adrenergic receptor  CI  confidence interval