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微重力效应下流体剪切所致的免疫细胞粘附动力学
学位论文
博士, 北京: 中国科学院大学, 2017
作者:
王成之
收藏
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浏览/下载:82/0
  |  
提交时间:2017/07/07
Epigenetic mechanisms: An emerging role in pathogenesis and its therapeutic potential in systemic sclerosis
期刊论文
The International Journal of Biochemistry & Cell Biology, 2015, 卷号: 67, 页码: 92-100
作者:
Luo, Yangyang
;
Wang, Yong
;
Shu, Ye
;
Lu, Qianjin
;
Xiao, Rong*
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/03
SSc
systemic sclerosis
SRC
scleroderma renal crisis
PAH
pulmonary arterial hypertension
SMR
standardized mortality ratio
DNMTs
DNA methyltransferases
SAM
S-adenosyl-methionine
5mC
5-methylcytosine
MBD
methyl-CpG-binding domain
Tet
ten–eleven translocation
HATs
histone acetyltransferases
HDACs
histone deacetylases
MiRNAs
microRNAs
MZ
monozygotic
DZ
dizygotic
MVECs
microvascular endothelial cells
FBs
fibroblasts
JAMs
junctional adhesion molecules
CTGF
connective tissue growth facto
TGF-β
transforming growth factor beta
CCN2
connective tissue growth factor
Fli1
Friend leukemia integration-1
TF
transcription factor
PECAM
platelet/endothelial cell adhesion molecule
PDGF
platelet derived growth factor
S1P1
sphingosin 1 phosphate
CXCL5
CXC chemokine ligand-5
BMPs
bone morphogenetic proteins
BMPRII
bone morphogenetic protein type II receptor
ET-1
endotheline-1
uPA
urokinase-type plasminogen activator
MBD
methyl-CpG-binding domain protein
ICAM
intercellular adhesion molecule
KLF5
Kruppel-like factor 5
Tregs
regulatory T cells
Runx1
Runt-related transcription factor 1
FOXP3
forkhead box protein 3 gene
ECM
extra cellular matrix
PDGF
platelet-derived growth factor
dSSc
diffuse systemic sclerosis
lSSc
limited systemic sclerosis
PCAF
protein-associated factor
Egr-1
early growth response 1
DDR2
discoidin domain receptor 2
TAB1
TGF-β activated kinase 1 binding protein 1
BAFF
B cell-activating factor
TSP-2
thrombospondin-2
MRTSS
Modified Rodnan total skin score
SDAI
Valentini scleroderma disease activity index
HC
healthy controls
SLE
systemic lupus erythematosus
SSD
scleroderma spectrum disorder
MTX
methylaminopterin
CYC
cyclophosphamide
MMF
mycophenolate mofetil
ACE
angiotensin converting enzyme
NO
nitric oxide
Systemic sclerosis
Epigenetic mechanisms
Biomarker
Therapy
Platelet endothelial cell adhesion molecule-1 (PECAM1) plays a critical role in the maintenance of human vascular endothelial barrier function
期刊论文
CELL BIOCHEMISTRY AND FUNCTION, 2015, 卷号: 33, 期号: 8, 页码: 560-565
作者:
Ren, Qi
;
Ren, Limin
;
Ren, Changjie
;
Liu, Xuefei
;
Dong, Chun
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/17
platelet endothelial cell adhesion molecule-1
tight junction
tight
junction associated protein
endothelium
barrier function
Platelet endothelial cell adhesion molecule-1 gene 125C/G polymorphism is associated with deep vein thrombosis
期刊论文
MOLECULAR MEDICINE REPORTS, 2015, 卷号: 12, 期号: 2, 页码: 2203-2210
作者:
Li, Gang
;
Han, Zong-Lin
;
Dong, He-Gui
;
Zhang, Xia
;
Kong, Xiang-Qian
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/17
deep vein thrombosis
platelet endothelial cell adhesion molecule-1
single nucleotide polymorphisms
Apelin and its receptor APJ in cardiovascular diseases
期刊论文
Clinica chimica acta, international journal of clinical chemistry, 2014, 卷号: 428, 页码: 1-8
作者:
Yu, Xiao-Hua*
;
Tang, Zhi-Bin
;
Liu, Li-Jing
;
Qian, Hong
;
Tang, Shi-Lin
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/27
ABCA1
ACAT1
APJ
ATP-binding cassette transporter A1
Ang II
Ang-1
Apelin
Atherosclerosis
BMP
BNP
CAD
COX-2
FGF2
GSK
HDAC
HIF-1alpha
Heart failure
Hypertension
ICAM-1
IRS1
JNK
MCP-1
MEF2
MIRI
NO
PAH
PDGF-BB
PGE2
PI3K
PKB
PKC
PPAR response elements
PPREs
TGF-beta
TNF-alpha
VCAM-1
VEGFA
VSMC
acyl coenzyme A:cholesterol acyltransferase-1
angiopoietin-1
angiotensin II
apo E
apolipoprotein E
bone morphogenic protein
brain natriuretic peptide
c-Jun N-terminal kinase
coronary heart disease
cyclooxygenase-2
fibroblast growth factor 2
glycogen synthase kinase
histone deacetylase
hypoxia-inducible factor 1alpha
insulin receptor substrate 1
intercellular adhesion molecule-1
monocyte chemoattractant protein-1
myocardial ischemia-reperfusion injury
myocyte enhancer factor 2
nitric oxide
phosphatidylinositol 3-kinase
platelet-derived growth factor-BB
prostaglandin E2
protein kinase B
protein kinase C
pulmonary arterial hypertension
transforming growth factor-beta
tumor necrosis factor-alpha
vascular cell adhesion molecule-1
vascular endothelial growth factor type A
vascular smooth muscle cell
An important role of matrix metalloproteinase-8 in angiogenesis in vitro and in vivo
期刊论文
Cardiovascular Research, 2013, 卷号: 99, 期号: 1, 页码: 146-155
作者:
Fang,C.
;
Wen,G.
;
Zhang,L.
;
Lin,L.
;
Moore,A.
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/23
β-catenin
Angiogenesis
Atherosclerosis
Matrix metalloproteinase-8
Migration
Platelet endothelial cell adhesion molecule-1
Proliferation
A novel family of RGD-containing disintegrins (Tablysin-15) from the salivary gland of the horsefly Tabanus yao targets αIIbβ3 or αVβ3 and inhibits platelet aggregation and angiogenesis
期刊论文
THROMBOSIS AND HAEMOSTASIS, 2011, 卷号: 105, 期号: 6, 页码: 1032-1045
作者:
Ma DY
;
Xu XQ
;
Andersen JF
;
Wang YP
;
Tokumasu F
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2016/03/23
Haematophagy
blood-sucking
disintegrin
thrombosis
sialogenins
Studies on anti-tumor and antimetastatic activities of fullerenol in a mouse breast cancer model
期刊论文
CARBON, 2010, 卷号: 48, 期号: 8, 页码: 2231-2243
作者:
Jiao, F
;
Liu, Y
;
Qu, Y
;
Li, W
;
Zhou, GQ
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2016/06/29
Platelet Endothelial Cell Adhesion Molecule-1, Stage-Specific Embryonic Antigen-1, and Flk-1 Mark Distinct Populations of Mouse Embryonic Stem Cells During Differentiation Toward Hematopoietic/Endothelial Cells
期刊论文
STEM CELLS AND DEVELOPMENT, 2010, 卷号: 19, 期号: 12, 页码: 1937-1948
作者:
Yue, W
;
Pi, QM
;
Zhang, WJ
;
Zhou, GD
;
Cui, L
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2015/07/22
P-Selectin Cross-Links PSGL-1 and Enhances Neutrophil Adhesion to Fibrinogen and ICAM-1 in a Src Kinase-Dependent, but GPCR-Independent Mechanism
期刊论文
CELL ADHESION & MIGRATION, 2007, 卷号: 1, 期号: 3, 页码: 115-123
作者:
Xu, T
;
Zhang, L
;
Geng, ZH
;
Wang, HB
;
Wang, JT
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2015/07/22
P-selectin (CD62P)
P-selectin glycoprotein ligand-1 (PSGL-1)
integrins
G protein-coupled receptor (GPCR)
human neutrophils
cell adhesion
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