CORC

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CORC

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Discovery of novel 3-hydroxypicolinamides as selective inhibitors of HIV-1 integrase-LEDGF/p75 interaction 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 125, 页码: 1051-1063
作者:  Zhang, Feng-Hua;  Debnath, Bikash;  Xu, Zhong-Liang;  Yang, Liu-Meng;  Song, Li-Rui
收藏  |  浏览/下载：13/0  |  提交时间：2019/01/08
Study of Structure-active Relationship for Inhibitors of HIV-1 Integrase LEDGF/p75 Interaction by Machine Learning Methods 期刊论文
2017, 卷号: 36, 期号: 7
作者:  Li, Yang;  Wu, Yanbin;  Yan, Aixia
收藏  |  浏览/下载：10/0  |  提交时间：2020/01/04
Discovery of novel 3-hydroxypicolinamides as selective inhibitors of HIV-1 integrase-LEDGF/p75 interaction 期刊论文
European Journal of Medicinal Chemistry, 2017, 卷号: 125, 期号: X, 页码: 1051-1063
作者:  Zhang FH;  Debnath B;  Zheng YT;  Neamati N[*];  Long YQ[*]
收藏  |  浏览/下载：72/0  |  提交时间：2016/11/07
2-Aryl-3-carbonylquinolones: Design, Synthesis and Biological Evaluation of Novel HCV NS5B Polymerase Inhibitors 期刊论文
ACTA CHIMICA SINICA, 2014, 卷号: 72, 期号: 8, 页码: 906-913
作者:  Wang Shenfeng;  Lin Jianping;  He Peilan;  Zuo Jianping;  Long Yaqiu
收藏  |  浏览/下载：14/0  |  提交时间：2019/01/08
Wikstroelide M potently inhibits HIV replication by targeting reverse transcriptase and integrase nuclear translocation 期刊论文
Chinese Journal of Natural Medicines, 2014, 卷号: 12, 期号: 3, 页码: 186-193
作者:  Zhang X;  Huang SZ;  Gu WG;  Yang LM;  Chen H
收藏  |  浏览/下载：18/0  |  提交时间：2014/06/03
Discovery of a novel HIV-1 integrase inhibitor from natural compounds through structure based virtual screening and cell imaging 期刊论文
FEBS LETTERS, 2014, 卷号: 588, 期号: 18, 页码: 3461-3468
作者:  Gu WG;  Zhang X;  Ip DTM;  Yang LM;  Zheng YT
收藏  |  浏览/下载：15/0  |  提交时间：2014/10/10
1,4-Bis(5-(naphthalen-1-yl)thiophen-2-yl)naphthalene, a small molecule, functions as a novel anti-HIV-1 inhibitor targeting the interaction between integrase and cellular Lens epithelium-derived growth factor 期刊论文
CHEMICO-BIOLOGICAL INTERACTIONS, 2014, 卷号: 213, 期号: X, 页码: 21-27
作者:  Gu WG;  Ip DTM;  Liu SJ;  Chan JH;  Wang Y
收藏  |  浏览/下载：14/0  |  提交时间：2014/10/15
2芳基3羰基喹诺酮新型hcvns5b多聚酶抑制剂的设计合成和活性评估 期刊论文
化学学报, 2014, 卷号: 72, 期号: 8, 页码: 906
作者:  王沈丰;  林建平;  何佩岚;  左建平;  龙亚秋
收藏  |  浏览/下载：2/0  |  提交时间：2020/07/01
Design of HIV-1 integrase inhibitors targeting the catalytic domain as well as its interaction with LEDGF/p75: A scaffold hopping approach using salicylate and catechol groups 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2011, 卷号: 19, 期号: 16, 页码: 4935-4952
作者:  Fan, Xing;  Zhang, Feng-Hua;  Al-Safi, Rasha I.;  Zeng, Li-Fan;  Shabaik, Yumna
收藏  |  浏览/下载：15/0  |  提交时间：2019/01/08
Inhibition of neurotrophin receptor p75 intramembran proteolysis by gamma-secretase inhibitor reduces medulloblastoma spinal metastasis 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2010, 卷号: 403, 期号: 3-4, 页码: 264-269
作者:  Wang, XiaoJi;  Cui, Min;  Wang, Lei;  Chen, XueHong;  Xin, Pan
收藏  |  浏览/下载：3/0  |  提交时间：2019/12/26

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