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复旦大学上海医学院 [6]
四川大学 [3]
上海生物化学与细胞生... [3]
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期刊论文 [25]
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Termipaniculatones A-F, chalcone-flavonone heterodimers from Terminthia paniculata, and their protective effects on hyperuricemia and acute gouty arthritis
期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 164, 页码: 228-235
作者:
Yang, Tong-Hua
;
Yan, De-Xiu
;
Huang, Xiao-Yan
;
Hou, Bo
;
Ma, Yun-Bao
收藏
  |  
浏览/下载:97/0
  |  
提交时间:2019/09/10
Terminthia paniculata (Wall. ex G. Don) CY Wu & TL Ming
Anacardiaceae
Termipaniculatones A-F
Chalcone-flavonone heterodimers
Xanthine oxidase inhibitors
Anti-gout potency
Leptin Promotes Monosodium Urate Crystal-Induced Inflammation in Human and Murine Models of Gout
期刊论文
JOURNAL OF IMMUNOLOGY, 2019, 卷号: 202, 期号: 9
作者:
Yu, Yiyun
;
Yang, Jie
;
Fu, Sisi
;
Xue, Yu
;
Liang, Minrui
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/12/05
Anthocyanin composition of fruit extracts from Lycium ruthenicum and their protective effect for gouty arthritis
期刊论文
INDUSTRIAL CROPS AND PRODUCTS, 2019, 卷号: 129
作者:
Zhang, Gong
;
Chen, Shasha
;
Zhou, Wu
;
Meng, Jing
;
Deng, Kai
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  |  
浏览/下载:50/0
  |  
提交时间:2019/11/26
Lycium ruthenicum Murray
Orbitrap MS
Anthocyanins extracts
Petunidin-3-glu
Gouty arthritis
Downregulation of Transcription Factor T-Bet as a Protective Strategy in Monosodium Urate-Induced Gouty Inflammation
期刊论文
2019, 卷号: 10, 期号: MAY
作者:
Yang, Qi-Bin[1]
;
He, Yong-Long[1,2]
;
Zhang, Quan-Bo[3]
;
Mi, Qing-Sheng[4]
;
Zhou, Jing-Guo[5]
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/16
Coptisine from Coptis chinensis blocks NLRP3 inflammasome activation by inhibiting caspase-1
期刊论文
PHARMACOLOGICAL RESEARCH, 2019, 卷号: 147, 页码: 104348
作者:
Wu, Jiasi
;
Luo, Yu
;
Jiang, Qing
;
Li, Sheng
;
Huang, Wenge
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2021/11/10
Coptisine
Caspase-1
NLRP3 inflammasome
NF-Kb
Gout
Reactive oxygen species promote tubular injury in diabetic nephropathy: The role of the mitochondrial ros-txnip-nlrp3 biological axis
期刊论文
Redox Biology, 2018, 卷号: 16, 页码: 32-46
作者:
Han, Yachun
;
Xu, Xiaoxuan
;
Tang, Chengyuan
;
Gao, Peng
;
Chen, Xianghui
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/12/03
ALT
alanine aminotransferase
AST
aspartate aminotransferase
BUN
blood urea nitrogen
BW
body weight
BG
blood glucose
DCFDA
dichlorodihydrofluorescein diacetate
DN
diabetic nephropathy
ECL
enhanced chemiluminescence
EM
electron microscopy
EMT
epithelial–mesenchymal transition
HbA1C
hemoglobin A1c
HE
hematoxylin-eosin
IF
immunofluorescence
IHC
immunohistochemistry
KW
kidney weight
LDL
low-density lipoprotein
MDA
malondialdehyde
MFI
median fluorescence intensity
MMP
mitochondrial transmembrane potential
MMT
methyl methane-thiosulphonate
MPTP
mitochondrial permeability transition pore
MSU
monosodium urate
MtROS
mitochondria reactive oxygen species
PAS
periodic acid-Schiff
Scr
serum creatinine
TC
total cholesterol
TG
triglyceride
TBARS
thiobarbituric acid reactive substances
TPP
triphenylphosphonium
TRX
thioredoxin
TXNIP
thioredoxin-interacting protein
TUNEL
terminal deoxynucleotidyl transferase dUTP nick end-labeling
8-OHdG
8-oxo-deoxyguanosine
UA
uric acid
Diabetic nephropathy
Mitochondria
Reactive oxygen species (ROS)
TRX/TXNIP
NLRP3 inflammasome
MitoQ
miR-155 is dispensable in monosodium urate-induced gouty inflammation in mice (vol 20, 144, 2018)
期刊论文
ARTHRITIS RESEARCH & THERAPY, 2018, 卷号: Vol.20
作者:
Yang, Qibin
;
Zhang, Quanbo
;
Qing, Yufeng
;
Zhou, Li
;
Mi, Qingsheng
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/02/25
Study on the expressions of NLRP3 gene transcript variants in peripheral blood monocytes of primary gout patients
期刊论文
CLINICAL RHEUMATOLOGY, 2018, 卷号: Vol.37 No.9, 页码: 2547-2555
作者:
Dang, Wantai
;
Xu, Dan
;
Xie, Wenguang
;
Zhou, Jingguo
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/02/25
Gout
Inflammasome
Monosodium urate crystals
NLRP3
Transcript variant
Inhibition of COX-2/mPGES-1 and 5-LOX in macrophages by leonurine ameliorates monosodium urate crystal-induced inflammation
期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2018, 卷号: 351
作者:
Liu, Yanzhuo
;
Duan, Chenfan
;
Chen, Honglei
;
Wang, Chenlong
;
Liu, Xiaoxiao
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/05
COX-2/mPGES-1/5-LOX
Macrophage
NLRP3 inflammasome
Leonurine
Gouty arthritis
Effectiveness of Osthole on Uric Acid Crystal-induced Acute Gouty Arthritis Through the Inhibition of NLRP3 Inflammasome
期刊论文
INTERNATIONAL JOURNAL OF PHARMACOLOGY, 2018, 卷号: 14, 期号: 8, 页码: 1169-1178
作者:
Yang, Ming[1]
;
Teng, Gaopeng[2]
;
Li, Guangjian[3]
;
Huang, Tao[4]
;
Xu, Renguo[5]
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/24
Osthole
Monosodium urate crystal (MSU)
arthritis
NLRP3 inflammasome
gouty arthritis
inflammatory factors
oxidative stress
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