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科研机构
大连化学物理研究所 [4]
厦门大学 [2]
西安交通大学 [2]
生物物理研究所 [1]
上海药物研究所 [1]
武汉病毒研究所 [1]
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期刊论文 [16]
发表日期
2019 [3]
2017 [1]
2016 [2]
2014 [2]
2012 [1]
2011 [4]
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Biochemica... [1]
生命有机化学 [1]
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(5R)-5-hydroxytriptolide ameliorates liver lipid accumulation by suppressing lipid synthesis and promoting lipid oxidation in mice
期刊论文
LIFE SCIENCES, 2019, 卷号: 232, 页码: 9
作者:
Dong, Yunxia
;
Lu, Henglei
;
Li, Qiang
;
Qi, Xinming
;
Li, Yuanchao
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/07/01
(5R)-5-hydroxytriptolide
NAFLD
Lipid synthesis
Fatty acids oxidation
Fat deposition
Integrated Metabolomics and Lipidomics Analyses Reveal Metabolic Reprogramming in Human Glioma with IDH1 Mutation
期刊论文
JOURNAL OF PROTEOME RESEARCH, 2019, 卷号: 18, 期号: 3, 页码: 960-969
作者:
Xu, Guowang
;
Zhou, Lina
;
Wang, Zhichao
;
Hu, Chunxiu
;
Zhang, Chaoqi
收藏
  |  
浏览/下载:74/0
  |  
提交时间:2019/06/20
glioma
IDH1
metabolomics
lipidomics
metabolic reprogramming
Integrated metabolomics and lipidomics analyses reveal metabolic reprogramming in human glioma with idh1 mutation
期刊论文
Journal of proteome research, 2019, 卷号: 18, 期号: 3, 页码: 960-969
作者:
Zhou, Lina
;
Wang, Zhichao
;
Hu, Chunxiu
;
Zhang, Chaoqi
;
Kovatcheva-Datchary, Petia
收藏
  |  
浏览/下载:90/0
  |  
提交时间:2019/05/08
Glioma
Idh1
Metabolomics
Lipidomics
Metabolic reprogramming
Comprehensive Analysis of Short-, Medium-, and Long-Chain AcylCoenzyme A by Online Two-Dimensional Liquid Chromatography/Mass Spectrometry
期刊论文
ANALYTICAL CHEMISTRY, 2017, 卷号: 89, 期号: 23, 页码: 12902-12908
作者:
Zhou, Lina
;
Xu, Guowang
;
Wang, Shuangyuan
;
Shi, Xianzhe
;
Wang, Zhichao
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/06/20
A Novel Missense Mutation in Very Long-chain Acyl-CoA Dehydrogenase Deficiency.
期刊论文
Indian pediatrics, 2016, 卷号: 53, 页码: 262
作者:
Bu Qingting
;
Pan Zhenyu
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/11/26
A Novel Missense Mutation in Very Long-chain Acyl-CoA Dehydrogenase Deficiency
期刊论文
INDIAN PEDIATRICS, 2016, 卷号: 53, 页码: 262-262
作者:
Bu, Qingting
;
Pan, Zhenyu
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/11/26
Operon for Biosynthesis of Lipstatin, the Beta-Lactone Inhibitor of Human Pancreatic Lipase
期刊论文
Appl. Environ. Microbiol., 2014, 卷号: 80, 期号: 24, 页码: 7473-7483
作者:
BAI TINGLI
;
Zhang DZ(张道忠)
;
LIN SHUANGJUN
;
LONG QINGSHAN
;
WANG YEMIN
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2016/08/30
Mindin/Spondin 2 inhibits hepatic steatosis, insulin resistance, and obesity via interaction with peroxisome proliferator-activated receptor α in mice
期刊论文
Journal of Hepatology, 2014, 卷号: 60, 期号: 5, 页码: 1046-1054
作者:
Zhu, Li-Hua
;
Wang, Aibing
;
Luo, Pengcheng
;
Wang, Xinan
;
Jiang, Ding-Sheng
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/23
IR
insulin resistance
WT
wild type
KO
knockout
TG
transgenic
NTG
non-transgenic
NC
normal chow
HFD
high-fat diet
PPARα
peroxisome proliferator-activated receptor alpha
ECM
extracellular matrix
NL
normal liver
NAFLD
non-alcoholic fatty liver disease
H&E
hematoxylin and eosin
ALT
alanine transaminase
AST
aspartate transaminase
ALP
alkaline phosphatase
HMGCR
3-hydroxy-3-methyl-glutaryl-CoA reductase
LDL
low density lipoprotein
HDL
high density lipoprotein
LDLR
low-density lipoprotein receptor
GPAT
glycerol-3-phosphate acyltransferase
DGAT
diglyceride acyltransferase
FFA
free fatty acid
SREBP1c
sterol response element binding protein 1c
ACC
acetyl-CoA carboxylase
FAS
fatty acid synthase
SCD
stearoyl-CoA desaturase
LXR-α
liver X receptor-α
ARG-1
arginase-1
ABCA
ATP-binding cassette transporter A
ABCG
ATP-binding cassette transporter G
CYP7A1
cytochrome P450, family 7, subfamily A, polypeptide 1
AMPK
AMP-activated protein kinase
IL
interleukin
TNF-α
tumor necrosis factor alpha
MCP-1
monocyte chemoattractant protein 1
MRC1
mannose receptor, C type 1
MGL
macrophage galactose-type C-type lectin
JNK
Jun N-terminal kinase
FBG
fasting glucose
HOMA-IR
homeostasis model assessment of insulin resistance
GTT
glucose tolerance test
ITT
intraperitoneal insulin tolerance test
Fins
fasting insulin
shRNA
short hairpin RNA
GFP
green fluorescent protein
IRS
insulin receptor substrate
Akt
protein kinase B
HSL
hormone sensitive lipase
ATGL
adipose triacylglycerol lipase
ACOX
acyl-coenzyme A oxidase
CPT-1α
carnitine palmitoyltransferase-1-α
LCAD
long-chain acyl-CoA dehydrogenase
MCAD
medium-chain acyl-CoA dehydrogenase
UCP
uncoupling protein
FGF21
fibroblast growth factor
PPRE
peroxisome proliferators response element
AUC
area under the curve
IKKβ
inhibitor of nuclear factor kappa B kinase beta subunit
Spondin 2
Fatty liver
Insulin resistance
PPARα
Global Liver Proteome Analysis Using iTRAQ Labeling Quantitative Proteomic Technology to Reveal Biomarkers in Mice Exposed to Perfluorooctane Sulfonate (PFOS)
期刊论文
environmental science & technology, 2012, 卷号: 46, 期号: 21, 页码: 12170-12177
作者:
Tan, Feng
;
Jin, Yihe
;
Liu, Wei
;
Quan, Xie
;
Chen, Jingwen
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2015/11/12
Role of suppressor of cytokine signaling 3 in lipid metabolism: analysis based on a phage-display human liver cdna library
期刊论文
Biochemical and biophysical research communications, 2011, 卷号: 416, 期号: 1-2, 页码: 39-44
作者:
Luo, Bin
;
Zou, Tingting
;
Lu, Nan
;
Chai, Fan
;
Ye, Xing
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/05/09
Obesity
Suppressor of cytokine signaling 3
Very-long-chain acyl-coa dehydrogenase
Leptin-resistance
Fatty acid beta-oxidation
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