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Optimized dose selective HDAC inhibitor tucidinostat overcomes anti-PD-L1 antibody resistance in experimental solid tumors 期刊论文
BMC Medicine, 2022, 卷号: 20, 期号: 1
作者:  Zhang,Pei;  Du,Yang;  Bai,Hua;  Wang,Zhijie;  Duan,Jianchun
收藏  |  浏览/下载:123/0  |  提交时间:2022/11/21
Biomimetic manganese-eumelanin nanocomposites for combined hyperthermia-immunotherapy against prostate cancer 期刊论文
Journal of Nanobiotechnology, 2022, 卷号: 20, 期号: 1
作者:  Liu,Yu;  Shang,Wenting;  Liu,Heng;  Hui,Hui;  Wu,Jun
收藏  |  浏览/下载:44/0  |  提交时间:2022/02/16
The Novel RET Inhibitor SYHA1815 Inhibits RET-Driven Cancers and Overcomes Gatekeeper Mutations by Inducing G1 Cell-Cycle Arrest through c-Myc Downregulation 期刊论文
MOLECULAR CANCER THERAPEUTICS, 2021, 卷号: 20, 期号: 11, 页码: 2198-2206
作者:  Jiang, Yuchen;  Peng, Xia;  Ji, Yinchun;  Dai, Yang;  Fang, Yanfen
收藏  |  浏览/下载:30/0  |  提交时间:2021/12/16
Pharmacodynamic, pharmacokinetic, and phase 1a study of bisthianostat, a novel histone deacetylase inhibitor, for the treatment of relapsed or refractory multiple myeloma 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:  Zhou, Yu-bo;  Zhang, Yang-ming;  Huang, Hong-hui;  Shen, Li-jing;  Han, Xiao-feng
收藏  |  浏览/下载:93/0  |  提交时间:2021/11/04
Development of Potent NEDD8-Activating Enzyme Inhibitors Bearing a Pyrimidotriazole Scaffold 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 9, 页码: 6161-6178
作者:  Xiong, Chaodong;  Zhou, Lina;  Tan, Jing;  Song, Shanshan;  Bao, Xubin
收藏  |  浏览/下载:33/0  |  提交时间:2021/08/17
Anti-DLBCL efficacy of DCZ0825 in vitro and in vivo: involvement of the PI3K-AKT-mTOR/JNK pathway 期刊论文
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2021, 卷号: 53, 期号: 5, 页码: 575-583
作者:  Hu, Ke;  Li, Bo;  Ma, Ruye;  Yi, Hongfei;  Xu, Zhijian
收藏  |  浏览/下载:68/0  |  提交时间:2021/06/11
Nanocrystal-loaded liposome for targeted delivery of poorly water-soluble antitumor drugs with high drug loading and stability towards efficient cancer therapy 期刊论文
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2021, 卷号: 599
作者:  Liang, Huamin;  Zou, Fengming;  Liu, Qingwang;  Wang, Beilei;  Fu, Liyi
收藏  |  浏览/下载:68/0  |  提交时间:2021/05/17
Third-generation EGFR inhibitor HS-10296 in combination with famitinib, a multi-targeted tyrosine kinase inhibitor, exerts synergistic antitumor effects through enhanced inhibition of downstream signaling in EGFR-mutant non-small cell lung cancer cells 期刊论文
THORACIC CANCER, 2021, 页码: 9
作者:  Zhang, Mi;  Quan, Haitian;  Fu, Li;  Li, Yun;  Fu, Haoyu
收藏  |  浏览/下载:19/0  |  提交时间:2021/05/24
Structure-Activity Relationship Study of Amidobenzimidazole Analogues Leading to Potent and Systemically Administrable Stimulator of Interferon Gene (STING) Agonists 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 3, 页码: 1649-1669
作者:  Song, Zilan;  Wang, Xiyuan;  Zhang, Yan;  Gu, Wangting;  Shen, Ancheng
收藏  |  浏览/下载:24/0  |  提交时间:2021/05/24
Nitrogen-containing bisphosphonate-loaded micro-arc oxidation coating for biodegradable magnesium alloy pellets inhibits osteosarcoma through targeting of the mevalonate pathway 期刊论文
ACTA BIOMATERIALIA, 2021, 卷号: 121, 页码: 682-694
作者:  Li, Mei;  Yao, Mengyu;  Wang, Weidan;  Wan, Peng;  Chu, Xiao
收藏  |  浏览/下载:22/0  |  提交时间:2021/03/15


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