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复旦大学上海医学院 [6]
上海药物研究所 [4]
厦门大学 [1]
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期刊论文 [10]
学位论文 [1]
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组氨酸激酶蛋白YycG活性与非活性状态的晶体结构研究
学位论文
2017, 2015
蔡永飞
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2017/06/20
组氨酸激酶
YycG
晶体结构
Histidine Kinase
YycG
Crystal structure
Anti-bacterial and Anti-biofilm Evaluation of Thiazolopyrimidinone Derivatives Targeting the Histidine Kinase YycG Protein of Staphylococcus epidermidis
期刊论文
FRONTIERS IN MICROBIOLOGY, 2017, 卷号: 8
作者:
Lv, Zhihui
;
Zhao, Dan
;
Chang, Jun
;
Liu, Huayong
;
Wang, Xiaofei
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  |  
浏览/下载:10/0
  |  
提交时间:2019/12/05
Staphylococcus epidermidis
histidine kinase YycG
minimal inhibitory concentration
minimal bactericidal concentration
anti-biofilm activity
Biological evaluation of halogenated thiazolo[3,2-a]pyrimidin-3-one carboxylic acid derivatives targeting the YycG histidine kinase
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2014, 卷号: 87
作者:
Zhao, Dan
;
Chen, Chen
;
Liu, Huayong
;
Zheng, Likang
;
Tong, Yao
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  |  
浏览/下载:10/0
  |  
提交时间:2019/12/19
Halogenated thiazolo[3.2-a]pyrimidin-3-one
Antibacterial activity
Antibiofilm activity
YycG histidine kinase inhibitor
Staphylococcus epidermidis
Staphylococcus aureus
Efficacy of novel antibacterial compounds targeting histidine kinase YycG protein
期刊论文
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2014, 卷号: 98, 期号: 13
作者:
Liu, Huayong
;
Zhao, Dan
;
Chang, Jun
;
Yan, Liang
;
Zhao, Fuju
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  |  
浏览/下载:4/0
  |  
提交时间:2019/12/19
Staphylococcus epidermidis
Methicillin-resistant Staphylococcus aureus (MRSA)
Antibacterial
Minimal inhibitory concentration (MIC)
Minimal bactericidal concentration (MBC)
Antibiofilmactivity
Thiazolidione derivatives targeting the histidine kinase YycG are effective against both planktonic and biofilm-associated Staphylococcus epidermidis
期刊论文
ACTA PHARMACOLOGICA SINICA, 2012, 卷号: 33, 期号: 3
作者:
Huang, Ren-zheng
;
Zheng, Li-kang
;
Liu, Hua-yong
;
Pan, Bin
;
Hu, Jian
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  |  
浏览/下载:5/0
  |  
提交时间:2019/12/19
Staphylococcus epidermidis
antibacterial agent
half maximal inhibitory concentration
minimal inhibitory concentration
biofilm-killing activity
Application of Histidine Kinase (YycG) in Screening Inhibitor of Streptococcus pneumoniae
期刊论文
Journal of Chinese Biotechnology, 2009, 卷号: 29, 期号: 3, 页码: 25-29
作者:
LI Nan
;
WANG Fei
;
NIU Si-qiang
;
WANG Hong
;
LI You-qiang
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/01/08
Histidine kinase
Purified protein
Enzymatic activity
Screening in vitro
Histidine kinase (YycG) protein of Streptococcus pneumoniae: Homology modeling and analysis
期刊论文
Chinese Journal of Biotechnology, 2009, 卷号: 25, 期号: 2, 页码: 207-214
作者:
Nan Li
;
Fei Wang
;
Wenchun Xu
;
Hong Wang
;
Xiaomin Luo
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  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
Streptococcus pneumoniae
two-component system
histidine kinase
homology modeling
molecular docking
Antimicrobial activities of YycG histidine kinase inhibitors against Staphylococcus epidermidis biofilms
期刊论文
FEMS MICROBIOLOGY LETTERS, 2007, 卷号: 273, 期号: 2, 页码: 149-156
作者:
Qin, Zhiqiang
;
Lee, Baoleri
;
Yang, Lei
;
Zhang, Jian
;
Yang, Xiaomei
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  |  
浏览/下载:10/0
  |  
提交时间:2019/01/08
biofilms
nosocomial infections
antibiotics
resistance
vancomycin
Antimicrobial activities of YycG histidine kinase inhibitors against Staphylococcus epidermidis biofilms
期刊论文
FEMS MICROBIOLOGY LETTERS, 2007, 卷号: 273, 期号: 2
作者:
Qin, Zhiqiang
;
Lee, Baoleri
;
Yang, Lei
;
Zhang, Jian
;
Yang, Xiaomei
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/19
biofilms
nosocomial infections
antibiotics
resistance
vancomycin
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