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上海药物研究所 [7]
上海营养与健康研究所 [5]
水生生物研究所 [3]
复旦大学上海医学院 [2]
上海中医药大学 [2]
生态环境研究中心 [2]
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期刊论文 [29]
学位论文 [2]
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2020 [1]
2019 [3]
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2015 [4]
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Loss of hnRNP A1 in murine skeletal muscle exacerbates high-fat diet-induced onset of insulin resistance and hepatic steatosis
期刊论文
JOURNAL OF MOLECULAR CELL BIOLOGY, 2020, 卷号: 12, 期号: 4, 页码: 277-290
作者:
Zhao, Mingxia
;
Shen, Lihong
;
Ouyang, Zijun
;
Li, Manru
;
Deng, Guoliang
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/12/24
hnRNP A1
insulin resistance
hepatic steatosis
glycogen synthesis
Simultaneous determination of imrecoxib and its two active metabolites in plasma of hepatic impairment patients by liquid chromatography-tandem mass spectrometry
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2019, 卷号: 1122, 页码: 58-63
作者:
Hou, Xiangyu
;
Dai, Xiaojian
;
Yang, Yong
;
Zhang, Yifan
;
Zhong, Dafang
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2020/07/01
Imrecoxib
Imrecoxib active metabolites
Pharmacokinetics
LC-MS/MS
Human
Moderate impairment
Population Pharmacokinetics Study of Nemonoxacin Among Chinese Patients With Moderate Hepatic Impairment
期刊论文
CLINICAL THERAPEUTICS, 2019, 卷号: 41, 期号: 3
作者:
Kang, Yue
;
Li, Yi
;
Xu, Fengyan
;
Zhang, Jing
;
Wang, Kun
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/12/05
hepatic impairment
nemonoxacin
pharmacokinetics
population pharmacokinetics
dose adjustment
Population Pharmacokinetics Study of Nemonoxacin Among Chinese Patients With Moderate Hepatic Impairment
期刊论文
Clinical Therapeutics, 2019
作者:
Yue Kang
;
Yi Li
;
Fengyan Xu
;
Jing Zhang
;
Kun Wang
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/12/17
hepatic impairment
nemonoxacin
pharmacokinetics
population pharmacokinetics
dose adjustment
AMP-Activated Protein Kinase (AMPK) Regulates Energy Metabolism through Modulating Thermogenesis in Adipose Tissue
期刊论文
FRONTIERS IN PHYSIOLOGY, 2018, 卷号: 9
作者:
Wu, Lingyan
;
Zhang, Lina
;
Li, Bohan
;
Jiang, Haowen
;
Duan, Yanan
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2019/01/08
AMP-activated protein kinase
thermogenesis
energy metabolism
A-769662
white adipose browning
PGC-1 alpha
Dysregulated bile acid signaling contributes to the neurological impairment in murine models of acute and chronic liver failure
期刊论文
EBIOMEDICINE, 2018, 卷号: 37
作者:
Xie, Guoxiang
;
Wang, Xiaoning
;
Jiang, Runqiu
;
Zhao, Aihua
;
Yan, Jingyu
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/12/05
Bile acids
Ammonia
Hepatic encephalopathy
Apical sodium-dependent bile acid transporter
Quantitative Estimation of Plasma Free Drug Fraction in Patients With Varying Degrees of Hepatic Impairment: A Methodological Evaluation
期刊论文
JOURNAL OF PHARMACEUTICAL SCIENCES, 2018, 卷号: 107, 期号: 7
作者:
Li, Guo-Fu
;
Yu, Guo
;
Li, Yanfei
;
Zheng, Yi
;
Zheng, Qing-Shan
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/05
plasma protein binding
fraction unbound
hepatic impairment
albumin
alpha 1-acid glycoprotein
clinical pharmacokinetics
physiologically based pharmacokinetics
Quantitative Estimation of Plasma Free Drug Fraction in Patients With Varying Degrees of Hepatic Impairment: A Methodological Evaluation
期刊论文
JOURNAL OF PHARMACEUTICAL SCIENCES, 2018, 卷号: 107, 期号: 7, 页码: 1948-1956
作者:
Li, Guo-Fu
;
Yu, Guo
;
Li, Yanfei
;
Zheng, Yi
;
Zheng, Qing-Shan
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/11
plasma protein binding
fraction unbound
hepatic impairment
albumin
alpha 1-acid glycoprotein
clinical pharmacokinetics
physiologically
based pharmacokinetics
Reduced production of laminin by hepatic stellate cells contributes to impairment in oval cell response to liver injury in aged mice
期刊论文
AGING-US, 2018, 卷号: 10, 期号: 12
作者:
Qian, Liu
;
Zhang, Hui
;
Gu, Yuting
;
Li, Dechun
;
He, Songbing
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/06
oval cells
hepatic stellate cells
aging
niche
DNA-dependent protein kinase
The impact of long term exposure to phthalic acid esters on reproduction in Chinese rare minnow (Gobiocypris rarus)
期刊论文
ENVIRONMENTAL POLLUTION, 2015, 卷号: 203, 页码: 130-136
作者:
Guo, Yongyong
;
Yang, Yuanjin
;
Gao, Yong
;
Wang, Xianfeng
;
Zhou, Bingsheng
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2015/09/14
Di-(2-ethylhexyl)-phthalate
Endocrine disruption
Reproductive toxicity
Environmental risk
Chinese rare minnow
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