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Identification of Betulinic Acid Derivatives as Potent TGR5 Agonists with Antidiabetic Effects via Humanized TGR5(H88Y) Mutant Mice 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 16, 页码: 12181-12199
作者:  Yun, Ying;  Zhang, Chenlu;  Guo, Shimeng;  Liang, Xiaoying;  Lan, Yuan
收藏  |  浏览/下载:42/0  |  提交时间:2021/11/04
A novel GPR120-selective agonist promotes insulin secretion and improves chronic inflammation 期刊论文
LIFE SCIENCES, 2021, 卷号: 269, 页码: 8
作者:  Yang, Liu;  Lei, Xian-Tao;  Huang, Qi;  Wang, Ting;  Sun, Hong-Bin
收藏  |  浏览/下载:23/0  |  提交时间:2021/05/24
The phosphatidylserine flippase beta-subunit Tmem30a is essential for normal insulin maturation and secretion 期刊论文
MOLECULAR THERAPY, 2021, 卷号: 29, 期号: 9
作者:  Yang, Yeming;  Sun, Kuanxiang;  Liu, Wenjing;  Li, Xiao;  Tian, Wanli
收藏  |  浏览/下载:28/0  |  提交时间:2021/11/18
TGR5 agonist ameliorates insulin resistance in skeletal muscles and improves glucose homeostasis in diabetic mice 期刊论文
METABOLISM-CLINICAL AND EXPERIMENTAL, 2019, 卷号: 99, 页码: 45-56
作者:  Huang, Suling;  Ma, Shanyao;  Ning, Mengmeng;  Yang, Wenji;  Ye, Yangliang
收藏  |  浏览/下载:24/0  |  提交时间:2020/07/01
Engineering human islet organoids from iPSCs using an organ-on-chip platform 期刊论文
LAB ON A CHIP, 2019, 卷号: 19, 期号: 6, 页码: 948-958
作者:  Deng, Pengwei;  Tao, Tingting;  Wang, Yaqing;  Chen, Wenwen;  Li, Zhongyu
收藏  |  浏览/下载:67/0  |  提交时间:2019/06/20
Engineering human islet organoids from ipscs using an organ-on-chip platform 期刊论文
Lab on a chip, 2019, 卷号: 19, 期号: 6, 页码: 948-958
作者:  Tao, Tingting;  Wang, Yaqing;  Chen, Wenwen;  Li, Zhongyu;  Su, Wentao
收藏  |  浏览/下载:85/0  |  提交时间:2019/05/08
Synthesis and biological evaluation of novel potent FFA1 agonists containing 2,3-dihydrobenzo[b][1,4]dioxine 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 6, 页码: 848-852
作者:  Kong, Deyu;  Guo, Shimeng;  Yang, Yushe;  Guo, Bin;  Xie, Xin
收藏  |  浏览/下载:28/0  |  提交时间:2020/07/01
Design and optimization of 2,3-dihydrobenzo[b][1,4]dioxine propanoic acids as novel GPR40 agonists with improved pharmacokinetic and safety profiles 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 22, 页码: 5780-5791
作者:  Guo, Bin;  Guo, Shimeng;  Huang, Jing;  Li, Jingya;  Li, Jia
收藏  |  浏览/下载:43/0  |  提交时间:2019/01/08
ETA as a novel Kv2.1 inhibitor ameliorates beta-cell dysfunction and hyperglycaemia 期刊论文
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, 2018, 卷号: 45, 期号: 12, 页码: 1257-1264
作者:  Zhou, Tingting;  Du, Mengfan;  Zhao, Tong;  Quan, Lingling;  Zhu, Zhiyuan
收藏  |  浏览/下载:94/0  |  提交时间:2019/01/08
Arsenite and methylarsonite inhibit mitochondrial metabolism and glucose-stimulated insulin secretion in INS-1 832/13 β cells 期刊论文
Archives of Toxicology, 2018, 卷号: 92, 期号: 2, 页码: 693-704
作者:  Dover, E N;  Beck, R;  Huang, M C;  Douillet, C;  Wang, Z
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/11


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