CORC

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CORC

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Discovery of Novel Allosteric Modulators Targeting an Extra-Helical Binding Site of GLP-1R Using Structure- and Ligand-Based Virtual Screening 期刊论文
BIOMOLECULES, 2021, 卷号: 11, 期号: 7, 页码: 14
作者:  Zhou, Qingtong;  Guo, Wanjing;  Dai, Antao;  Cai, Xiaoqing;  Vass, Marton
收藏  |  浏览/下载：41/0  |  提交时间：2021/08/17
Pharmacological characterization of mono-, dual- and tri-peptidic agonists at GIP and GLP-1 receptors 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2020, 卷号: 177, 页码: 13
作者:  Yuliantie, Elita;  Darbalaei, Sanaz;  Dai, Antao;  Zhao, Peishen;  Yang, Dehua
收藏  |  浏览/下载：22/0  |  提交时间：2020/12/24
Discovery of thiophene-containing biaryl amide derivatives as novel glucagon receptor antagonists 期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2018, 卷号: 92, 期号: 1, 页码: 1241-1254
作者:  Li, Jia;  Feng, Yang;  Li, Huihui;  Shu, Shuangjie;  Dai, Antao
收藏  |  浏览/下载：26/0  |  提交时间：2019/01/08
A novel series of 4-methyl substituted pyrazole derivatives as potent glucagon receptor antagonists: Design, synthesis and evaluation of biological activities 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 8, 页码: 1896-1908
作者:  Shu, Shuangjie;  Dai, Antao;  Wang, Jiang;  Wang, Bin;  Feng, Yang
收藏  |  浏览/下载：20/0  |  提交时间：2019/01/08
High-throughput identification of G protein-coupled receptor modulators through affinity mass spectrometry screening 期刊论文
CHEMICAL SCIENCE, 2018, 卷号: 9, 期号: 12, 页码: 3192-3199
作者:  Qin, Shanshan;  Meng, Mengmeng;  Yang, Dehua;  Bai, Wenwen;  Lu, Yan
收藏  |  浏览/下载：42/0  |  提交时间：2019/01/08
A novel series of 4-methyl substituted pyrazole derivatives as potent glucagon receptor antagonists: Design, synthesis and evaluation of biological activities 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 8
作者:  Shu, Shuangjie;  Dai, Antao;  Wang, Jiang;  Wang, Bin;  Feng, Yang
收藏  |  浏览/下载：9/0  |  提交时间：2019/12/05
DMT efficiently inhibits hepatic gluconeogenesis by regulating the G alpha q signaling pathway 期刊论文
JOURNAL OF MOLECULAR ENDOCRINOLOGY, 2017, 卷号: 59, 期号: 2, 页码: 151-169
作者:  Zhou, Ting-Ting;  Ma, Fei;  Shi, Xiao-Fan;  Xu, Xin;  Du, Te
收藏  |  浏览/下载：33/0  |  提交时间：2019/01/08
Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators 期刊论文
NATURE, 2017, 卷号: 546, 期号: 7657, 页码: 312-+
作者:  Song, Gaojie;  Yang, Dehua;  Wang, Yuxia;  de Graaf, Chris;  Zhou, Qingtong
收藏  |  浏览/下载：30/0  |  提交时间：2019/01/08
Solvent-accessibility of discrete residue positions in the polypeptide hormone glucagon by F-19-NMR observation of 4-fluorophenylalanine 期刊论文
JOURNAL OF BIOMOLECULAR NMR, 2017, 卷号: 68, 期号: 1, 页码: 1-6
作者:  Hou, Yaguang;  Hu, Wanhui;  Li, Xiaona;  Skinner, John J.;  Liu, Dongsheng
收藏  |  浏览/下载：24/0  |  提交时间：2019/01/08
Design, synthesis, structure-activity relationships, and docking studies of pyrazole-containing derivatives as a novel series of potent glucagon receptor antagonists 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2016, 卷号: 24, 期号: 12, 页码: 2852-2863
作者:  Shu, Shuangjie;  Cai, Xiaoqing;  Li, Jia;  Feng, Yang;  Dai, Antao
收藏  |  浏览/下载：18/0  |  提交时间：2019/01/08

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