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科研机构
上海药物研究所 [3]
生态环境研究中心 [3]
中南大学 [2]
复旦大学上海医学院 [2]
上海中医药大学 [2]
北京大学 [1]
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期刊论文 [21]
发表日期
2020 [1]
2019 [2]
2018 [3]
2017 [4]
2016 [2]
2015 [3]
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The steroid receptor coactivator 1 (SRC1) and 3 (SRC3) recruitment as novel molecular initiating event of 4-n-nonylphenol in estrogen receptor alpha-mediated pathways
期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2020, 卷号: 189, 页码: 1-8
作者:
Ji, Xiaoya
;
Li, Na
;
Yang, Rong
;
Rao, Kaifeng
;
Ma, Mei
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2021/09/15
4-n-Nonylphenol
Estrogenic activity
Molecular initiating event (MIE)
Estrogen receptor alpha (ER alpha)
Steroid receptor coactivator (SRC)
Evaluation of selected traditional Chinese medical extracts for bone mineral density maintenance: A mechanistic study.
期刊论文
Journal of traditional and complementary medicine, 2019, 卷号: 9, 期号: 3
作者:
Rebhun John F
;
Du Qin
;
Hood Molly
;
Guo Hailing
;
Glynn Kelly M
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2019/12/05
Anti-inflammatory
BMD, bone mineral density
BSA, bovine serum albumin
Bmp4, bone morphogenic protein 4
CRE, cyclic adenosine monophosphate response element
CREB, cyclic adenosine monophosphate response element binding protein
DEXA, dual-energy X-ray absorptiometry
DMSO, Dimethyl sulfoxide
Drynaria fortunei
E2, estradiol
ER, estrogen receptor
ERE, estrogen response element
Epimedium brevicornu
Estrogenic
FBS, fetal bovine serum
Fsk, forskolin
Hprt, hypoxanthine-guanine phosphoribosyl-transferase
IL-1, interleukin 1
LBD, ligand binding domain
LBM, low bone mass
M-CSF, macrophage colony-stimulating factor
MAPK, mitogen activated protein kinase
NF-κβ, nuclear factor kappa beta
OP, osteoporosis
Osteoporosis
PTH, parathyroid hormone
PTHrp, PTH related peptide
RANKL, receptor activator of nuclear factor kappa beta ligand
RLU, relative luminescence unit
ROI, region of interest
Runx2, runt-related transcription factor 2
SFM, serum free media
TCM, traditional Chinese medicine
TNFα, tumor necrosis factor alpha
TRAP, tartrate-resistant acid phosphatase
UAS, upstream activating sequence
cAMP, cyclic adenosine monophosphate
qPCR, quantitative polymerase chain reaction
Effects of acute and chronic zinc exposure on steroid hormone receptor expression in the lined seahorse, Hippocampus erectus
期刊论文
JOURNAL OF THE WORLD AQUACULTURE SOCIETY, 2019, 卷号: 50, 期号: 3, 页码: 659, 673
作者:
Li, Chunyan
;
Lin, Qiang
;
Wang, Xin
;
Zhang, Bo
;
Qin, Geng
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2019/09/09
gene expression
metabolism
seahorse
steroid hormone receptor
zinc
Radix Paeoniae Alba increases serum estrogen level and up-regulates estrogen receptor expression in uterus and vagina of immature/ovariectomized mice
期刊论文
Phytotherapy research : PTR, 2018
作者:
Xu, Ying
;
Li, Xin
;
Chen, Ting
;
Qu, Ya-Kun
;
Zheng, Hong-Xia
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2019/01/08
Cholestasis-induced bile acid elevates estrogen level via farnesoid X receptor-mediated suppression of the estrogen sulfotransferase SULT1E1
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 33
作者:
Liu, Xijun
;
Xue, Ruyi
;
Yang, Caiting
;
Gu, Jianxin
;
Chen, She
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/05
acetylation
cAMP response element-binding protein (CREB)
estrogen receptor
bile acid
nuclear receptor
Determination of hypoxia-inducible factor-1 by using a ratiometric colorimetric test based on click-mediated growth of gold nanoparticles
期刊论文
MICROCHIMICA ACTA, 2018, 卷号: 185, 页码: 451
作者:
Chen, Hong[1]
;
Sun, Yan[2]
;
Li, Yifei[3]
;
Zhao, Jing[4]
;
Cao, Ya[5]
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/04/22
Transcription factor
Click chemistry
Hypoxia response element
Alkynyl-functionalized gold nanoparticle
Cu+-alkynyl complex
Seed-mediated growth
Gold nanostructure
Estrogen receptor alpha
The flavonol glycoside icariin promotes bone formation in growing rats by activating the cAMP signaling pathway in primary cilia of osteoblasts
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2017, 卷号: 292, 页码: 20883-20896
作者:
Wei, Zhenlong
;
Ma, Huiping
;
Xian, Cory J.
;
Wang, Jufang
;
Chen, Keming
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2018/05/31
Combination of metformin with chemotherapeutic drugs via different molecular mechanisms
期刊论文
Cancer Treatment Reviews, 2017, 卷号: 54, 页码: 24-33
作者:
Peng, Mei*
;
Darko, Kwame Oteng
;
Tao, Ting
;
Huang, Yanjun
;
Su, Qiongli
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/03
AIs
aromatase inhibitors
AMPK
Adenosine Monophosphate-Activated Protein Kinase
AR
androgen
ATM
Ataxia Telangiectasia Mutated
ATP
Adenosine Triphosphate
BCSS
breast cancer specific survival
CK-MB
Creatine Kinase-MB
CREB1
cAMP Response Element-Binding Protein 1
CSC
cancer stem cell
DFS
disease-free survival
DHFU
dihydrofluorouracil
DPD
dihydropyrimidine dehydrogenase
EpCAM
Epithelial Cell Adhesion Molecule
ER
estrogen
ERCC1
excision repair cross-complementary 1
ERK
extracellular signal-regulated kinases
EZH2
enhancer of zeste homolog 2
FdUMP
fluorodeoxyuridine monophosphate
FdUTP
fluorodeoxyuridine triphosphate
FHC
ferritin heavy chain
FUTP
fluorouridine triphosphate
HbA1C
hemoglobin A1c
HER
Human Epidermal Growth Factor Receptor
HIF-1α
hypoxia-inducible factor-1α
HK
hexokinase
IGF1R
insulin growth factor 1 receptor
LDH
lactate dehydrogenase
MDA
Muscular Dystrophy Association
MMP
Matrix Metallopeptidase
MRP1
multidrug resistance-associated protein 1
mTOR
mammalian target of rapamycin
MTX
methotrexate
NCCN
National Comprehensive Cancer Network
OS
overall survival
pCR
Pathologic Complete Response
PDGFR
platelet-derived growth factor receptors
PFS
progression-free survival
PKA
protein kinase A
PR
progesterone receptor
RFS
relapse-free survival
SOD
superoxide dismutase
TAM
tamoxifen
TCA
tricarboxlic acid
TS
thymidylate synthase
Combination
Mechanisms
Metformin
Chemotherapeutic drugs
Pregnane X receptor regulates the AhR/Cyp1A1 pathway and protects liver cells from benzo-[α]-pyrene-induced DNA damage
期刊论文
Toxicology Letters, 2017, 卷号: 275, 页码: 67-76
作者:
Cui, Hongmei
;
Gu, Xinsheng
;
Chen, Jingshu
;
Xie, Ying
;
Ke, Sui
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/23
PXR
pregnane X receptor
AhR
aryl hydrocarbon receptor
DRE
dioxin response element
BaP
benzo[a]pyrene
RIF
rifampicin
H2Ax
histone 2Ax
CAR
constitutive androstane receptor
FXR
farnesoid X receptor
CYP450
cytochrome P450
EROD
7-ethoxyresorufin-O-deethylase
PAH
polycyclic aromatic hydrocarbon
ER
estrogen receptor
PXR
AhR
BaP
cyp1a1
DNA damages
Exploring the pharmacological mechanism of Yanghe Decoction on HER2-positive breast cancer by a network pharmacology approach
期刊论文
Journal of Ethnopharmacology, 2017, 卷号: 199, 页码: 68-85
作者:
Zeng, Luting*
;
Yang, Kailin
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/27
ER
estrogen receptor
PGR
progesterone receptor
HER
human epidermal growth factor receptor
CAM
complementary and alternative medicine
TCM
traditional Chinese medicine
YHD
Yanghe Decoction
OB
oral bioavailability
DL
drug-likeness
PPI
protein-protein interaction
GO
Gene Ontology
IGFR
insulin-like growth factor receptor
HB-EGF
heparin-binding growth factor
EGFR
epidermal growth factor receptor
PRE
progesterone response element
TGF
transforming growth factor
HDAC
histone deacetylase
CDK
cyclin dependent kinases
EMT
epithelial-mesenchymal transition
IGFBP
IGF-binding protein
FGFR
fibroblast growth factor receptor
Yanghe Decoction
HER2-positive breast cancer
Network pharmacology
Traditional Chinese medicine
Chinese medicine formulae
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