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The steroid receptor coactivator 1 (SRC1) and 3 (SRC3) recruitment as novel molecular initiating event of 4-n-nonylphenol in estrogen receptor alpha-mediated pathways 期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2020, 卷号: 189, 页码: 1-8
作者:  Ji, Xiaoya;  Li, Na;  Yang, Rong;  Rao, Kaifeng;  Ma, Mei
收藏  |  浏览/下载:9/0  |  提交时间:2021/09/15
Evaluation of selected traditional Chinese medical extracts for bone mineral density maintenance: A mechanistic study. 期刊论文
Journal of traditional and complementary medicine, 2019, 卷号: 9, 期号: 3
作者:  Rebhun John F;  Du Qin;  Hood Molly;  Guo Hailing;  Glynn Kelly M
收藏  |  浏览/下载:44/0  |  提交时间:2019/12/05
Anti-inflammatory  BMD, bone mineral density  BSA, bovine serum albumin  Bmp4, bone morphogenic protein 4  CRE, cyclic adenosine monophosphate response element  CREB, cyclic adenosine monophosphate response element binding protein  DEXA, dual-energy X-ray absorptiometry  DMSO, Dimethyl sulfoxide  Drynaria fortunei  E2, estradiol  ER, estrogen receptor  ERE, estrogen response element  Epimedium brevicornu  Estrogenic  FBS, fetal bovine serum  Fsk, forskolin  Hprt, hypoxanthine-guanine phosphoribosyl-transferase  IL-1, interleukin 1  LBD, ligand binding domain  LBM, low bone mass  M-CSF, macrophage colony-stimulating factor  MAPK, mitogen activated protein kinase  NF-κβ, nuclear factor kappa beta  OP, osteoporosis  Osteoporosis  PTH, parathyroid hormone  PTHrp, PTH related peptide  RANKL, receptor activator of nuclear factor kappa beta ligand  RLU, relative luminescence unit  ROI, region of interest  Runx2, runt-related transcription factor 2  SFM, serum free media  TCM, traditional Chinese medicine  TNFα, tumor necrosis factor alpha  TRAP, tartrate-resistant acid phosphatase  UAS, upstream activating sequence  cAMP, cyclic adenosine monophosphate  qPCR, quantitative polymerase chain reaction  
Effects of acute and chronic zinc exposure on steroid hormone receptor expression in the lined seahorse, Hippocampus erectus 期刊论文
JOURNAL OF THE WORLD AQUACULTURE SOCIETY, 2019, 卷号: 50, 期号: 3, 页码: 659, 673
作者:  Li, Chunyan;  Lin, Qiang;  Wang, Xin;  Zhang, Bo;  Qin, Geng
收藏  |  浏览/下载:46/0  |  提交时间:2019/09/09
Radix Paeoniae Alba increases serum estrogen level and up-regulates estrogen receptor expression in uterus and vagina of immature/ovariectomized mice 期刊论文
Phytotherapy research : PTR, 2018
作者:  Xu, Ying;  Li, Xin;  Chen, Ting;  Qu, Ya-Kun;  Zheng, Hong-Xia
收藏  |  浏览/下载:48/0  |  提交时间:2019/01/08
Cholestasis-induced bile acid elevates estrogen level via farnesoid X receptor-mediated suppression of the estrogen sulfotransferase SULT1E1 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 33
作者:  Liu, Xijun;  Xue, Ruyi;  Yang, Caiting;  Gu, Jianxin;  Chen, She
收藏  |  浏览/下载:5/0  |  提交时间:2019/12/05
Determination of hypoxia-inducible factor-1 by using a ratiometric colorimetric test based on click-mediated growth of gold nanoparticles 期刊论文
MICROCHIMICA ACTA, 2018, 卷号: 185, 页码: 451
作者:  Chen, Hong[1];  Sun, Yan[2];  Li, Yifei[3];  Zhao, Jing[4];  Cao, Ya[5]
收藏  |  浏览/下载:8/0  |  提交时间:2019/04/22
The flavonol glycoside icariin promotes bone formation in growing rats by activating the cAMP signaling pathway in primary cilia of osteoblasts 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2017, 卷号: 292, 页码: 20883-20896
作者:  Wei, Zhenlong;  Ma, Huiping;  Xian, Cory J.;  Wang, Jufang;  Chen, Keming
收藏  |  浏览/下载:37/0  |  提交时间:2018/05/31
Combination of metformin with chemotherapeutic drugs via different molecular mechanisms 期刊论文
Cancer Treatment Reviews, 2017, 卷号: 54, 页码: 24-33
作者:  Peng, Mei*;  Darko, Kwame Oteng;  Tao, Ting;  Huang, Yanjun;  Su, Qiongli
收藏  |  浏览/下载:13/0  |  提交时间:2019/12/03
AIs  aromatase inhibitors  AMPK  Adenosine Monophosphate-Activated Protein Kinase  AR  androgen  ATM  Ataxia Telangiectasia Mutated  ATP  Adenosine Triphosphate  BCSS  breast cancer specific survival  CK-MB  Creatine Kinase-MB  CREB1  cAMP Response Element-Binding Protein 1  CSC  cancer stem cell  DFS  disease-free survival  DHFU  dihydrofluorouracil  DPD  dihydropyrimidine dehydrogenase  EpCAM  Epithelial Cell Adhesion Molecule  ER  estrogen  ERCC1  excision repair cross-complementary 1  ERK  extracellular signal-regulated kinases  EZH2  enhancer of zeste homolog 2  FdUMP  fluorodeoxyuridine monophosphate  FdUTP  fluorodeoxyuridine triphosphate  FHC  ferritin heavy chain  FUTP  fluorouridine triphosphate  HbA1C  hemoglobin A1c  HER  Human Epidermal Growth Factor Receptor  HIF-1α  hypoxia-inducible factor-1α  HK  hexokinase  IGF1R  insulin growth factor 1 receptor  LDH  lactate dehydrogenase  MDA  Muscular Dystrophy Association  MMP  Matrix Metallopeptidase  MRP1  multidrug resistance-associated protein 1  mTOR  mammalian target of rapamycin  MTX  methotrexate  NCCN  National Comprehensive Cancer Network  OS  overall survival  pCR  Pathologic Complete Response  PDGFR  platelet-derived growth factor receptors  PFS  progression-free survival  PKA  protein kinase A  PR  progesterone receptor  RFS  relapse-free survival  SOD  superoxide dismutase  TAM  tamoxifen  TCA  tricarboxlic acid  TS  thymidylate synthase  Combination  Mechanisms  Metformin  Chemotherapeutic drugs  
Pregnane X receptor regulates the AhR/Cyp1A1 pathway and protects liver cells from benzo-[α]-pyrene-induced DNA damage 期刊论文
Toxicology Letters, 2017, 卷号: 275, 页码: 67-76
作者:  Cui, Hongmei;  Gu, Xinsheng;  Chen, Jingshu;  Xie, Ying;  Ke, Sui
收藏  |  浏览/下载:13/0  |  提交时间:2019/12/23
Exploring the pharmacological mechanism of Yanghe Decoction on HER2-positive breast cancer by a network pharmacology approach 期刊论文
Journal of Ethnopharmacology, 2017, 卷号: 199, 页码: 68-85
作者:  Zeng, Luting*;  Yang, Kailin
收藏  |  浏览/下载:4/0  |  提交时间:2019/12/27
ER  estrogen receptor  PGR  progesterone receptor  HER  human epidermal growth factor receptor  CAM  complementary and alternative medicine  TCM  traditional Chinese medicine  YHD  Yanghe Decoction  OB  oral bioavailability  DL  drug-likeness  PPI  protein-protein interaction  GO  Gene Ontology  IGFR  insulin-like growth factor receptor  HB-EGF  heparin-binding growth factor  EGFR  epidermal growth factor receptor  PRE  progesterone response element  TGF  transforming growth factor  HDAC  histone deacetylase  CDK  cyclin dependent kinases  EMT  epithelial-mesenchymal transition  IGFBP  IGF-binding protein  FGFR  fibroblast growth factor receptor  Yanghe Decoction  HER2-positive breast cancer  Network pharmacology  Traditional Chinese medicine  Chinese medicine formulae  


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