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上海药物研究所 [26]
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兰州理工大学 [5]
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厦门大学 [2]
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Uncommon N-Methoxyindolediketopiperazines from Acrostalagmus luteoalbus, a Marine Algal Isolate of Endophytic Fungus
期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2021, 页码: 7
作者:
Cao, Jin
;
Li, Xiao-Ming
;
Li, Xin
;
Li, Hong-Lei
;
Konuklugil, Belma
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2021/09/18
Marine alga
Endophytic fungus
Acrostalagmus luteoalbus
Natural products
Biological activity
Discovery and Biological Evaluation of New Selective Acetylcholinesterase Inhibitors with Anti-A beta Aggregation Activity through Molecular Docking-Based Virtual Screening
期刊论文
CHEMICAL & PHARMACEUTICAL BULLETIN, 2020, 卷号: 68, 期号: 2, 页码: 161-166
作者:
Liu, Guangpu
;
Jiao, Yang
;
Lin, Yongqiang
;
Hao, Haifang
;
Dou, Yanli
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2020/07/01
selective acetylcholinesterase inhibitor
amyloid beta aggregation
neuroprotectant
molecular docking
molecular dynamics simulation
Protective effects of phenformin on zebrafish embryonic neurodevelopmental toxicity induced by X-ray radiation
期刊论文
ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY, 2019, 卷号: 47, 期号: 1, 页码: 4202-4210
作者:
Gan, Lu
;
Guo, Menghuan
;
Si, Jing
;
Zhang, Jinhua
;
Liu, Zhiyuan
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/01/19
X-ray irradiation
zebrafish
phenformin
neurodevelopmental protective effects
Anti-BACE1 and anti-AchE activities of undescribed spiro-dioxolane-containing meroterpenoids from the endophytic fungus Aspergillus terreus Thom
期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 165, 页码: 8
作者:
Qi, Changxing
;
Zhou, Qun
;
Gao, Weixi
;
Liu, Mengting
;
Chen, Chunmei
收藏
  |  
浏览/下载:82/0
  |  
提交时间:2019/10/14
Aspergillus terreus Thom
endophytic fungus
3,5-Dimethylorsellinic acid-based meroterpenoid
Adducts
Alzheimer's disease
Discovery of New Selective Butyrylcholinesterase (BChE) Inhibitors with Anti-A beta Aggregation Activity: Structure-Based Virtual Screening, Hit Optimization and Biological Evaluation
期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 14, 页码: 21
作者:
Jiang, Cheng-Shi
;
Ge, Yong-Xi
;
Cheng, Zhi-Qiang
;
Wang, Yin-Yin
;
Tao, Hong-Rui
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2020/07/01
selective BChE inhibitor
virtual screening
structural optimization
molecular dynamics
anti-A beta aggregation
Lycofargesiines A-F, further Lycopodium alkaloids from the club moss Huperzia fargesii
期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 162, 页码: 183-192
作者:
Xiong, Juan
;
Meng, Wei-Jia
;
Zhang, Hai-Yan
;
Zou, Yike
;
Wang, Wen-Xuan
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2020/07/01
Huperzia fargesii
Lycopodiaceae
Lycopodium alkaloids
Lycofargesiines
anti-AChE
Discovery of new multifunctional selective acetylcholinesterase inhibitors: structure-based virtual screening and biological evaluation
期刊论文
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 2019, 卷号: 33, 期号: 5, 页码: 521-530
作者:
Jiang, Cheng-Shi
;
Ge, Yong-Xi
;
Cheng, Zhi-Qiang
;
Song, Jia-Li
;
Wang, Yin-Yin
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/07/01
AChE inhibitor
Pharmacophore model
Molecular docking
Anti-A aggregation
Neuroprotective activity
Lycofargesiines A-F, further Lycopodium alkaloids from the club moss Huperzia fargesii
期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 162
作者:
Xiong, Juan
;
Meng, Wei-Jia
;
Zhang, Hai-Yan
;
Zou, Yike
;
Wang, Wen-Xuan
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/12/05
Huperzia fargesii
Lycopodiaceae
Lycopodium alkaloids
Lycofargesiines
anti-AChE
Sex-dependent effects of sulfamethoxazole exposure on pro-/anti-oxidant status with stimulation on growth, behavior and reproduction in the amphipod Hyalella azteca
期刊论文
ENVIRONMENTAL POLLUTION, 2019, 卷号: Vol.244, 页码: 398-404
作者:
Yu, Zhenyang
;
Yin, Daqiang
;
Zhang, Jing
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/17
Sulfonamide
Antioxidant
capacity
Oxidative
stress
AChE
activity
Behavior
Reproduction
Development of chalcone-O-alkylamine derivatives as multifunctional agents against Alzheimer's disease
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 183, 页码: 111737
作者:
Bai, Ping
;
Wang, Keren
;
Zhang, Pengfei
;
Shi, Jian
;
Cheng, Xinfeng
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2021/11/04
Alzheimer's disease
Chalcone-O-Alkylamine derivatives
Multi-functional agents
Rational design
Synthesis
Precognitive effect
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