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CORC

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Allosteric Modulators Enhancing GLP-1 Binding to GLP-1R via a Transmembrane Site 期刊论文
ACS CHEMICAL BIOLOGY, 2021, 卷号: 16, 期号: 11, 页码: 2444-2452
作者:  Wang, Jiang;  Yang, Dehua;  Cheng, Xi;  Yang, Linlin;  Wang, Zhaohui
收藏  |  浏览/下载：27/0  |  提交时间：2022/01/04
Activation pathway of a G protein-coupled receptor uncovers conformational intermediates as targets for allosteric drug design 期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 15
作者:  Lu, Shaoyong;  He, Xinheng;  Yang, Zhao;  Chai, Zongtao;  Zhou, Shuhua
收藏  |  浏览/下载：35/0  |  提交时间：2021/11/04
Discovery of Novel Allosteric Modulators Targeting an Extra-Helical Binding Site of GLP-1R Using Structure- and Ligand-Based Virtual Screening 期刊论文
BIOMOLECULES, 2021, 卷号: 11, 期号: 7, 页码: 14
作者:  Zhou, Qingtong;  Guo, Wanjing;  Dai, Antao;  Cai, Xiaoqing;  Vass, Marton
收藏  |  浏览/下载：41/0  |  提交时间：2021/08/17
Molecular insights into ago-allosteric modulation of the human glucagon-like peptide-1 receptor 期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 11
作者:  Cong, Zhaotong;  Chen, Li-Nan;  Ma, Honglei;  Zhou, Qingtong;  Zou, Xinyu
收藏  |  浏览/下载：46/0  |  提交时间：2021/08/17
Affinity Mass Spectrometry-Based Fragment Screening Identified a New Negative Allosteric Modulator of the Adenosine A(2A) Receptor Targeting the Sodium Ion Pocket 期刊论文
ACS CHEMICAL BIOLOGY, 2021, 卷号: 16, 期号: 6, 页码: 991-1002
作者:  Lu, Yan;  Liu, Hongyue;  Yang, Dehua;  Zhong, Li;  Xin, Ye
收藏  |  浏览/下载：25/0  |  提交时间：2021/08/17
Targeted Proteomics Combined with Affinity Mass Spectrometry Analysis Reveals Antagonist E7 Acts As an Intracellular Covalent Ligand of Orphan Receptor GPR52 期刊论文
ACS CHEMICAL BIOLOGY, 2020, 卷号: 15, 期号: 12, 页码: 3275-3284
作者:  Ma, Mengna;  Guo, Shimeng;  Lin, Xi;  Li, Shanshan;  Wu, Yiran
收藏  |  浏览/下载：16/0  |  提交时间：2021/05/24
Discovery of an Inhibitor for the TREK-1 Channel Targeting an Intermediate Transition State of Channel Gating 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 19, 页码: 10972-10983
作者:  Ma, Yuqin;  Luo, Qichao;  Fu, Jie;  Che, Yanxin;  Guo, Fei
收藏  |  浏览/下载：11/0  |  提交时间：2021/05/24
GABA(B) receptor pas de deux: insights from high-resolution structures 期刊论文
CELL RESEARCH, 2020, 页码: 2
作者:  Jiang, Yi;  Xu, H. Eric
收藏  |  浏览/下载：2/0  |  提交时间：2020/12/24
Recent advances in dopaminergic strategies for the treatment of Parkinson's disease 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 12
作者:  Mao, Qi;  Qin, Wang-zhi;  Zhang, Ao;  Ye, Na
收藏  |  浏览/下载：27/0  |  提交时间：2020/07/01
Allosteric Regulation of Hsp90 alpha's Activity by Small Molecules Targeting the Middle Domain of the Chaperone 期刊论文
ISCIENCE, 2020, 卷号: 23, 期号: 2, 页码: 46
作者:  Zhou, Chen;  Zhang, Chi;  Zhu, Hongwen;  Liu, Zhijun;  Su, Haixia
收藏  |  浏览/下载：143/0  |  提交时间：2020/07/01

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