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Gefitinib enhances the anti-tumor immune response against EGFR-mutated NSCLC by upregulating B7H5 expression and activating T cells via CD28H
期刊论文
INTERNATIONAL JOURNAL OF ONCOLOGY, 2022, 卷号: 61
作者:
Guo, Huihui
;
Zhang, Xilin
;
Xie, Shangzhi
;
Chen, Tianwei
;
Xie, Dong
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2022/12/22
gefitinib
CD28H
NSCLC
EGFR mutation
Matrix stiffness exacerbates the proinflammatory responses of vascular smooth muscle cell through the DDR1-DNMT1 mechanotransduction axis
期刊论文
BIOACTIVE MATERIALS, 2022, 卷号: 17, 页码: 406-424
作者:
Wang, Jin
;
Xie, Si-an
;
Li, Ning
;
Zhang, Tao
;
Yao, Weijuan
收藏
  |  
浏览/下载:105/0
  |  
提交时间:2022/06/10
Matrix stiffness
Inflammation
DDR1
DNMT1
Mechanotransduction
Binding Pattern Reconstructions of FGF-FGFR Budding-Inducing Signaling in Reef-Building Corals
期刊论文
FRONTIERS IN PHYSIOLOGY, 2022, 卷号: 12, 页码: 12
作者:
Guo, Zhuojun
;
Liao, Xin
;
Chen, J. -Y.(陈均远)
;
He, Chunpeng
;
Lu, Zuhong
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2022/02/24
reef-building coral
budding reproduction
receptor tyrosine kinase
full-length transcriptome
FGF-FGFR binding models
Profiling Receptor Tyrosine Kinase Fusions in Chinese Breast Cancers
期刊论文
FRONTIERS IN ONCOLOGY, 2021, 卷号: 11
作者:
Tao, Zhonghua
;
Liu, Jianxia
;
Li, Ting
;
Xu, Hong
;
Chen, Kai
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2022/01/10
receptor tyrosine kinase
gene fusion
genomic rearrangments
breast cancer
next-generation sequencing
Discovery of a potent, selective, and covalent ZAP-70 kinase inhibitor
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 219, 页码: 12
作者:
Rao, Danni
;
Li, Heng
;
Ren, Xuelian
;
Sun, Yaoliang
;
Wen, Cuiyun
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2021/08/17
Zeta-chain associated protein kinase 70 kDa (ZAP-70)
Covalent inhibitor
T cell
Autoimmune diseases
DW14383 is an irreversible pan-FGFR inhibitor that suppresses FGFR-dependent tumor growth in vitro and in vivo
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:
Dai, Meng-di
;
Wang, Yue-liang
;
Fan, Jun
;
Dai, Yang
;
Ji, Yin-chun
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2021/05/24
receptor tyrosine kinase
FGFR inhibitor
DW14383
antitumor activity
Synthesis of triazolotriazine derivatives as c-Met inhibitors
期刊论文
MOLECULAR DIVERSITY, 2020, 页码: 8
作者:
Guo, Yuting
;
Peng, Xia
;
Ji, Yinchun
;
Zhang, Yitong
;
Ding, Jian
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2020/12/24
Receptor tyrosine kinase
c-Met
Triazolotriazine
SAR
Cellular potency
Distinct co-acquired alterations and genomic evolution during TKI treatment in non-small-cell lung cancer patients with or without acquired T790M mutation
期刊论文
ONCOGENE, 2020, 卷号: 39
作者:
Jin, Ying
;
Bao, Hua
;
Le, Xiuning
;
Fan, Xiaojun
;
Tang, Ming
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/11/26
Solution structure, dynamics and function investigation of Kringle domain of human receptor tyrosine kinase-like orphan receptor 1
期刊论文
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2020
作者:
Ma, Xiaofang
;
Liu, Bin
;
Yang, Jiahui
;
Hu, Kaifeng
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2021/01/05
A putative insulin receptor involved in immune response of Chinese mitten crab Eriocheir sinensis
期刊论文
ISJ-INVERTEBRATE SURVIVAL JOURNAL, 2020, 卷号: 18, 页码: 1-10
作者:
Wang, L.
;
Chen, H.
;
Qiu, L.
;
Wang, L.
;
Song, L.
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/04/21
Aeromonas hydrophila infection
chinese mitten crab
insulin receptor
immune response
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