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科研机构
北京大学 [11]
厦门大学 [9]
上海药物研究所 [9]
南海海洋研究所 [7]
南华大学 [6]
复旦大学上海医学院 [6]
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期刊论文 [104]
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E3 ubiquitin ligase NEDD4L negatively regulates inflammation by promoting ubiquitination of MEKK2
期刊论文
EMBO REPORTS, 2022
作者:
Li, Hui
;
Wang, Ning
;
Jiang, Yu
;
Wang, Haofei
;
Xin, Zengfeng
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2022/12/22
IL-17R signaling
inflammation
MEKK2
NEDD4L
ubiquitination
FPS-ZM1 inhibits LPS-induced microglial inflammation by suppressing JAK/STAT signaling pathway
期刊论文
INTERNATIONAL IMMUNOPHARMACOLOGY, 2021, 卷号: 100, 页码: 12
作者:
Wang, Lan
;
Zhao, Danfeng
;
Wang, Huan
;
Wang, Lele
;
Liu, Xiaohui
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2021/12/01
Inflammation
Microglia
LPS
RNA-seq
JAK
STAT signaling pathway
Exogenous FABP4 interferes with differentiation, promotes lipolysis and inflammation in adipocytes
期刊论文
ENDOCRINE, 2020, 卷号: 67, 期号: 3, 页码: 587-596
作者:
Dou, Hui-Xia
;
Wang, Ting
;
Su, Hai-Xia
;
Gao, Ding-Ding
;
Xu, Ye-Chun
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2020/07/01
eFABP4
Adipocyte
Differentiation
Lipolysis
Inflammation
Expression and functional analysis of tumor necrosis factor receptor (TNFR)-associated factor 5 from Nile tilapia, Oreochromis niloticus
期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2019, 卷号: 93, 期号: 1, 页码: 781-788
作者:
Xia, Hongli
;
Li, Yuan
;
Wang, Zhiwen
;
Chen, Wenjie
;
Cheng, Jun
收藏
  |  
浏览/下载:178/0
  |  
提交时间:2019/11/29
TRAF5
Oreochromis niloticus
Streptococcus agalactiae
Signal transduction
Helicobacter pylori-downregulated tumor necrosis factor receptor-associated protein 1 mediates apoptosis of human gastric epithelial cells
期刊论文
JOURNAL OF CELLULAR PHYSIOLOGY, 2019, 卷号: 234, 期号: 9
作者:
Zou, Quanming
;
Teng, Yongsheng
;
Liu, Xin
;
Han, Bin
;
Ma, Qiang
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/04
apoptosis
gastric epithelial cells
Helicobacter pylori
TRAP1
vacA
MET Inhibitors Promote Liver Tumor Evasion of the Immune Response by Stabilizing PDL1
期刊论文
GASTROENTEROLOGY, 2019, 卷号: 156, 期号: 6
作者:
Li, Hui
;
Li, Chia-Wei
;
Li, Xiaoqiang
;
Din, Qingqing
;
Guo, Lei
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/12/05
Programmed Cell Death Ligand 1
Hepatocellular Carcinoma
Tumor Necrosis Factor Receptor-Associated Factor 6
Glycogen Synthase Kinase 3
Anthocyanins from Lycium ruthenicum Murr. Ameliorated D-Galactose-Induced Memory Impairment, Oxidative Stress, and Neuroinflammation in Adult Rats
期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2019, 卷号: 67, 期号: 11
作者:
Chen, Shasha
;
Zhou, Haonan
;
Zhang, Gong
;
Meng, Jing
;
Deng, Kai
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2019/11/26
Lycium ruthenicum Murr
anthocyanins
oxidative stress
memory impairment
neuroinflammation
neurodegeneration
Total glucosides of paeony improve complete freund's adjuvant-in-duced rheumatoid arthritis in rats by inhibiting toll-like receptor 2-mediated tumor necrosis factor receptor-associated factor 6/nuclear factor-kappa B pathway activation
期刊论文
2019, 卷号: 39, 期号: 4, 页码: 566-574
作者:
Chen Huan[1,2]
;
Wen Yueqiang[1,2]
;
Pan Ting[1,2]
;
Xu Shijun[1,2]
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/16
IMM-H004 therapy for permanent focal ischemic cerebral injury via CKLF1/CCR4-mediated NLRP3 inflammasome activation
期刊论文
2019, 卷号: 212, 页码: 36-53
作者:
Ai Q D
;
Chen Chen
;
Chu Shifeng
;
Zhang Zhao
;
Luo Yun
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/01/03
ASC = apoptosis-associated speck-like protein containing a caspase activation recruitment domain
BCA = bicinchoninic acid
BSA = bovine serum albumin
CCA = common carotid artery
CCR4 = C-C chemokine receptor type 4
CKLF1 = chemokine-like factor 1
CO-IP = coimmunoprecipitation
ECA = external carotid artery
ELISA = enzyme-linked immunosorbent assay
FDA = Food and Drug Administration
I/R = ischemic/reperfusion
ICA = internal carotid artery
IL-18 = interleukin 18
IL-1β = interleukin 1β
LDH = lactate dehydrogenase
NLRP3 = NOD-like receptor protein 3
PBS = phosphate-buffered saline
SD = standard deviation
TNF-α = tumor necrosis factor α
TTC = 2
3
5-triphenyltetrazolium-chloride
WT = wild-type
pMCAO = permanent middle cerebral artery occlusion
pro-Caspase-1 = precursor Caspase-1
qPCR = quantitative real-time PCR
tMCAO = transient middle cerebral artery occlusion
tPA = tissue plasminogen activator
NK cells in cerebral ischemia
期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, 卷号: 109, 页码: 547-554
作者:
Chen, Chen
;
Ai, Qi-Di
;
Chu, Shi-Feng
;
Zhang, Zhao
;
Chen, Nai-Hong*
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2019/12/27
tPA
tissue plasminogen activator
IS
ischemic stroke
BBB
blood-brain barrier
IFN-γ
interferon-γ
pMCAO
permanent middle cerebral artery occlusion
tMCAO
transient middle cerebral artery occlusion
CX3CR1
CX3CL1 receptor
CNS
central nervous system
AchE
acetylcholine esterase
CFSE
arboxyfluorescein diacetate succinimidyl ester
HI
hypoxic ischemia
MCAO IP-10
interferon-inducible protein-10
IL
interleukin
GFAP
glial fibrillary acidic protein
tg
transgenic
WT
wild-type
APC
antigen presenting cell
SAI
stroke-associated infection
STAT3
signal transducer and activator of transcription-3
HPA
hypothalamic-pituitary-adrenal
cSVD
cerebral small vessel disease
SHR
spontaneously hypertensive rat
CSF
cerebrospinal fluid
aSAH
aneurysmal subarachnoid hemorrhage
DCI
delayed cerebral ischemia
MRI
magnetic resonance imaging
CT
computed tomography
EVs
extracellular vesicles
MSC
mesenchymal stem cell
MNCs
bone marrow-derived mononuclear cells
CpG-ODN
cytosine-guanine oligodideoxynucleotide
TLR9
toll-like receptor 9
TNF
tumor necrosis factor
NK cells
Cerebral ischemia
Inflammation
Immunodpression
Infection
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