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上海药物研究所 [25]
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期刊论文 [39]
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浏览/检索结果:
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Sarsasapogenin improves adipose tissue inflammation and ameliorates insulin resistance in high-fat diet-fed C57BL/6J mice
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 10
作者:
Yu, Yan-yan
;
Cui, Shi-chao
;
Zheng, Tian-nan
;
Ma, Hai-jian
;
Xie, Zhi-fu
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/12/24
insulin resistance
sarsasapogenin
adipose tissue inflammation
macrophage-adipocyte crosstalk
IKK/NF-kappa B
JNK
Identifying the active components of Baihe-Zhimu decoction that ameliorate depressive disease by an effective integrated strategy: a systemic pharmacokinetics study combined with classical depression model tests
期刊论文
CHINESE MEDICINE, 2019, 卷号: 14, 期号: 1, 页码: 11
作者:
Zhong, Ming
;
Tian, Xiaoting
;
Chen, Shuoji
;
Chen, Mingcang
;
Guo, Ziqiong
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/07/01
Baihe-Zhimu decoction
Antidepressant
Timosaponin BII
Timosaponin BIII
Drug discovery
Enhanced Anti-diabetic Effect of Berberine Combined With Timosaponin B2 in Goto-Kakizaki Rats, Associated With Increased Variety and Exposure of Effective Substances Through Intestinal Absorption
期刊论文
FRONTIERS IN PHARMACOLOGY, 2019, 卷号: 10, 页码: 15
作者:
Tian, Xiaoting
;
Liu, Fang
;
Li, Zhixiong
;
Lin, Yunfei
;
Liu, Huan
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/07/01
berberine
timosaponin B2
diabetes
combination treatments
drug-drug interaction
metabolites
hepatic metabolism
intestinal absorption
Metabolism, pharmacokinetics, and hepatic disposition of xanthones and saponins on Zhimu treatments for exploratively interpreting the discrepancy between the herbal safety and timosaponin A3-induced hepatotoxicity
期刊论文
Acta pharmacologica Sinica, 2018, 卷号: 39, 期号: 12, 页码: 1923-1934
作者:
Xie, Yang
;
Zhou, Xu
;
Pei, Hu
;
Chen, Ming-Cang
;
Sun, Zhao-Lin
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  |  
浏览/下载:92/0
  |  
提交时间:2019/01/08
Timosaponin AIII inhibits the growth of human leukaemia cells HL-60 by down-regulation of PI3K/AKT and Wnt/beta-catenin pathways
期刊论文
BIOTECHNOLOGY & BIOTECHNOLOGICAL EQUIPMENT, 2018, 卷号: 32, 期号: 1
作者:
Zhang, Sai
;
Pang, Haifeng
;
Sun, Meihua
;
Li, Haibo
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  |  
浏览/下载:7/0
  |  
提交时间:2019/12/05
TSA-III
leukaemia cell
proliferation
apoptosis
signalling pathway
metabolismpharmacokineticsandhepaticdispositionofxanthonesandsaponinsonzhimutreatmentsforexplorativelyinterpretingthediscrepancybetweentheherbalsafetyandtimosaponina3inducedhepatotoxicity
期刊论文
actapharmacologicasinica, 2018, 卷号: 39, 期号: 12, 页码: 1923
作者:
Xie Yang
;
Zhou Xu
;
Pei Hu
;
Chen Mingcang
;
Sun Zhaolin
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/07/01
B-II
LIVER-INJURY
IN-VITRO
ANEMARRHENA-ASPHODELOIDES
OXIDATIVE STRESS
RAT PLASMA
A-III
MANGIFERIN
NORATHYRIOL
EXTRACT
Zhimu
timosaponin A3
mangiferin
pharmacokinetics
metabolism
hepatotoxicity
antioxidant
[Inhibitory mechanisms of timosaponin AⅢ on proliferation and growth of human glioblastoma cells].
期刊论文
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2017, 卷号: 42, 期号: 6
作者:
Tan Xi
;
;
Pan Hui-Jun
;
;
Wu Wei-da
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
MAPK signal pathway
Wnt/β-Catenin signal pathway
Cell proliferation
Human glioblastoma cell U87MG
Timosaponin AⅢ
Timosaponin B-III exhibits antidepressive activity in a mouse model of postpartum depression by the regulation of inflammatory cytokines, BNDF signaling and synaptic plasticity
期刊论文
EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2017, 卷号: 14, 期号: 4
作者:
Zhang, Xiao-Li
;
Wang, Lin
;
Xiong, Li
;
Huang, Feng-Hua
;
Xue, Han
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/05
depression
timosaponin B-III
forced swimming test
tail suspension test
inflammatory cytokines
bone-derived neurotrophic factor signaling pathway
synaptic plasticity
Pharmacokinetics of mangiferin and its metabolite-Norathyriol, Part 2: Influence of UGT, CYP450, P-gp, and enterobacteria and the potential interaction in Rhizoma Anemarrhenae decoction with timosaponin B2 as the major contributor
期刊论文
BIOFACTORS, 2016, 卷号: 42, 期号: 5, 页码: 545-555
作者:
Tian, Xiaoting
;
Xu, Zhou
;
Li, Zhixiong
;
Ma, Yuanjie
;
Lian, Shan
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
mangiferin
norathyriol
pharmacokinetics
drug-drug interaction
timosaponin B2
Rhizoma Anemarrhenae
The rapid antidepressant and anxiolytic-like effects of yy-21 involve enhancement of excitatory synaptic transmission via activation of mtor signaling in the mpfc
期刊论文
European neuropsychopharmacology, 2016, 卷号: 26, 期号: 7, 页码: 1087-1098
作者:
Guo, Fei
;
Zhang, Bing
;
Fu, Zhiwen
;
Ma, Yuqin
;
Gao, Yu
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2019/05/09
Yy-21
Mtor
Synaptic transmission
Synaptic proteins
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