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Design, Synthesis, and Biological Evaluation of Novel Biotinylated Podophyllotoxin Derivatives as Potential Antitumor Agents
期刊论文
FRONTIERS IN CHEMISTRY, 2019, 卷号: 7, 页码: 14
作者:
Zi, Cheng-Ting
;
Gao, Yin-Sheng
;
Yang, Liu
;
Feng, Shu-Yun
;
Huang, Yue
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浏览/下载:80/0
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提交时间:2019/07/29
podophyllotoxin derivatives
biotin
anticancer activity
synthesis
apoptosis
Idarubicin Stimulates Cell Cycle- and TET2-Dependent Oxidation of DNA 5-Methylcytosine in Cancer Cells
期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2019, 卷号: 32, 期号: 5, 页码: 861-868
作者:
Zhong, Shangwei
;
Li, Cuiping
;
Han, Xiao
;
Li, Xiangjun
;
Yang, Yun-Gui
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浏览/下载:25/0
  |  
提交时间:2020/10/21
Design, Synthesis, and Biological Evaluation of Novel DNA Gyrase-Inhibiting Spiropyrimidinetriones as Potent Antibiotics for Treatment of Infections Caused by Multidrug-Resistant Gram-Positive Bacteria
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 6, 页码: 2950-2973
作者:
Shi, Chenghui
;
Zhang, Yinyong
;
Wang, Ting
;
Lu, Wenchao
;
Zhang, Shuhua
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  |  
浏览/下载:16/0
  |  
提交时间:2020/07/01
Effect of expression levels of multidrug resistance gene-related protein 1, P-glycoprotein and topoisomerase II on paclitaxel, gemcitabine and vinorelbine sensitivity in pulmonary cancer
期刊论文
TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH, 2019, 卷号: 18, 期号: 8
作者:
Min, Na Di Er Yi
;
Bai Yunbiao
;
Gao Kaiheng
;
Hao Zhenhua
;
Tan Yulong
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  |  
浏览/下载:22/0
  |  
提交时间:2019/12/05
Lung carcinoma
Drug resistance gene
Drug sensitivity
Chemotherapy
Multidrug resistance gene-related protein
Antiproliferative and Enzyme Docking Analysis of Engleromycin from Engleromyces goetzei
期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 1, 页码: 9
作者:
Guo, Mingquan
;
Ma, Hong
;
Chen, Guilin
;
Zhang, Yongli
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  |  
浏览/下载:48/0
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提交时间:2019/03/05
Engleromyces goetzei
engleromycin
antiproliferative activities
molecular docking
Structural and Metal Ion Effects on Human Topoisomerase IIα Inhibition by α--Heterocyclic Thiosemicarbazones
期刊论文
Chemical Research in Toxicology, 2019, 卷号: Vol.32 No.1, 页码: 90-99
作者:
William H. Morris
;
Lana Ngo
;
James T. Wilson
;
Wathsala Medawala
;
Anthony R. Brown
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  |  
浏览/下载:3/0
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提交时间:2019/12/13
Synthetic optimization of ellipticine and antitumor activity of novel hexacyclic derivatives of ellipticine
期刊论文
2019
作者:
Lin Jingjing
;
Tang Mei
;
Zhao Ru
;
Du Qianqian
;
Shen Longying
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  |  
浏览/下载:14/0
  |  
提交时间:2020/01/03
Antitumor activity
Ellipticine
Hexacyclic derivatives
Synthesis
Topoisomerase IIα inhibitor
Rapid re-evaluation of bioactive saponins from Paris polyphylla using affinity ultrafiltration-LC/MS with multiple drug targets
期刊论文
INTERNATIONAL JOURNAL OF MASS SPECTROMETRY, 2018, 卷号: 434, 页码: 87-92
作者:
Guo, Mingquan
;
Chen, Guilin
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  |  
浏览/下载:58/0
  |  
提交时间:2018/12/29
Ultrafiltration-LC/MS
Polyphyllin
Topoisomerase I and II
Cyclooxygenase 2
Multiple drug targets
Synthesis and In Vitro Antitumor Activity of Novel Bivalent -Carboline-3-carboxylic Acid Derivatives with DNA as a Potential Target
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018, 卷号: 19, 期号: 10
作者:
Gu, Hongling
;
Li, Na
;
Dai, Jiangkun
;
Xi, Yaxi
;
Wang, Shijun
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  |  
浏览/下载:30/0
  |  
提交时间:2019/01/08
bivalent -carbolines
antitumor
apoptosis
DNA-binding affinity
bcl-2
New tanshinone I derivatives S222 and S439 similarly inhibit topoisomerase I/II but reveal different p53-dependency in inducing G2/M arrest and apoptosis
期刊论文
BIOCHEMICAL PHARMACOLOGY, 2018, 卷号: 154, 页码: 255-264
作者:
Tian, Qian-Ting
;
Ding, Chun-Yong
;
Song, Shan-Shan
;
Wang, Ying-Qing
;
Zhang, Ao
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  |  
浏览/下载:40/0
  |  
提交时间:2019/01/08
Tanshinone-1
S222
S439
Anticancer targets
DNA topoisomerases
P53
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