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上海药物研究所 [6]
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期刊论文 [31]
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Natural Potent NAAA Inhibitor Atractylodin Counteracts LPS-Induced Microglial Activation
期刊论文
FRONTIERS IN PHARMACOLOGY, 2020, 卷号: 11, 页码: 9
作者:
Yang, Longhe
;
Ji, Chunyan
;
Li, Yitian
;
Hu, Fan
;
Zhang, Fang
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  |  
浏览/下载:20/0
  |  
提交时间:2020/12/10
NAAA inhibitor
atractylodin
>
anti-inflammation
microglia
traditional Chinese medicine
USP28 and USP25 are downregulated by Vismodegib in vitro and in colorectal cancer cell lines
期刊论文
FEBS JOURNAL, 2020, 页码: 18
作者:
Wang, Hui
;
Meng, Qian
;
Ding, Yiluan
;
Xiong, Muya
;
Zhu, Mengying
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  |  
浏览/下载:84/0
  |  
提交时间:2020/12/24
colorectal cancer
HDX-MS
inhibitor
USP25
USP28
Vismodegib
Structure-Dependent Modulation of Substrate Binding and Biodegradation Activity of Pirin Proteins toward Plant Flavonols
期刊论文
ACS CHEMICAL BIOLOGY, 2019, 卷号: 14, 期号: 12, 页码: 2629-2640
作者:
Guo, Bin
;
Zhang, Yichen
;
Hicks, Gregory
;
Huang, Xingrong
;
Li, Rongfeng
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  |  
浏览/下载:46/0
  |  
提交时间:2020/03/20
Unique N-glycosylation of a recombinant exo-inulinase from Kluyveromyces cicerisporus and its effect on enzymatic activity and thermostability
期刊论文
Journal of Biological Engineering, 2019, 卷号: 13, 期号: 1
作者:
Ma,Junyan
;
Li,Qian
;
Tan,Haidong
;
Jiang,Hao
;
Li,Kuikui
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  |  
浏览/下载:275/0
  |  
提交时间:2019/12/02
N-glycosylation
Exo-inulinase
β-Sandwich domain
Enzyme activity
Thermostability
A novel SGNH family hydrolase Ali5 with thioesterase activity and a GNSL motif but without a classic GDSL motif from Altererythrobacter ishigakiensis
期刊论文
BIOTECHNOLOGY LETTERS, 2019, 卷号: 41, 期号: 4-5
作者:
Jian, Shu-Ling
;
Huo, Ying-Yi
;
Cheng, Hong
;
Hu, Xiao-Jian
;
Li, Jixi
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  |  
浏览/下载:24/0
  |  
提交时间:2019/12/05
Altererythrobacter ishigakiensis NBRC 107699(T)
GNSL motif
SGNH family esterase
Substrate binding cavity
Thioesterase
A novel SGNH family hydrolase Ali5 with thioesterase activity and a GNSL motif but without a classic GDSL motif from Altererythrobacter ishigakiensis
期刊论文
BIOTECHNOLOGY LETTERS, 2019, 卷号: 41, 期号: 4-5, 页码: 591-604
作者:
Hong, Li-Guo[1]
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浏览/下载:23/0
  |  
提交时间:2019/12/24
Altererythrobacter ishigakiensis NBRC 107699(T)
GNSL motif
SGNH family esterase
Substrate binding cavity
Thioesterase
Reversal of multidrug resistance by Marsdenia tenacissima and its main active ingredients polyoxypregnanes
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2017, 卷号: 203, 页码: 110-119
作者:
To, Kenneth K. W.
;
Wu, Xu
;
Yin, Chun
;
Chai, Stella
;
Yao, Sheng
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  |  
浏览/下载:55/0
  |  
提交时间:2019/01/08
ABCG2
Multidrug resistance
Marsdenia tenacissima
MRP1
P-glycoprotein
Polyoxypregnane compounds
Structural and mechanistic insights into the biosynthesis of CDP-archaeol in membranes
期刊论文
CELL RESEARCH, 2017, 卷号: 27, 期号: 11, 页码: 1378-1391
作者:
Ren, SX
;
Caforio, A
;
Yang, Q
;
Sun, B
;
Yu, F
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  |  
浏览/下载:48/0
  |  
提交时间:2018/08/30
Diacylglycerol Synthase
Escherichia-coli
Force-field
Saccharomyces-cerevisiae
Diglyceride Synthetase
Protein Topogenesis
Purification
Lipids
Crystallography
Features
Switching on Supramolecular Catalysis via Cavity Mediation and Electrostatic Regulation
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2016, 卷号: 55, 期号: 41, 页码: 12778-12782
作者:
Qiao, Yupu
;
Zhang, Long
;
Li, Jia
;
Lin, Wei
;
Wang, Zhenqiang
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  |  
浏览/下载:21/0
  |  
提交时间:2017/01/11
calixarenes
container molecules
Knoevenagel condensation
supramolecular catalysis
tetraalkylammonium
Functional and structural analysis of Pichia pastoris-expressed Aspergillus niger 1,4-beta-endoglucanase
期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2016, 卷号: 475, 期号: 1, 页码: 8-12
作者:
Yan, Junjie
;
Liu, Weidong
;
Li, Yujie
;
Lai, Hui-Lin
;
Zheng, Yingying
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  |  
浏览/下载:43/0
  |  
提交时间:2017/03/21
1,4-beta-Endoglucanase
Aspergillus niger
Pichia pastoris
Crystal structure
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