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The identification of novel small-molecule inhibitors targeting WDR5-MLL1 interaction through fluorescence polarization based high-throughput screening 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 4, 页码: 638-645
作者:  Ye, Xiaoqing;  Zhang, Rukang;  Lian, Fulin;  Zhang, Weiyao;  Lu, Wenchao
收藏  |  浏览/下载:3/0  |  提交时间:2020/07/01
A Fusion Protein of the p53 Transaction Domain and the p53-Binding Domain of the Oncoprotein MdmX as an Efficient System for High-Throughput Screening of MdmX Inhibitors 期刊论文
BIOCHEMISTRY, 2017, 卷号: 56, 期号: 25, 页码: 3273-3282
作者:  Qin, Lingyun;  Zhou, Jingjing;  Su, Zhengding;  Liu, Huili;  Huang, Yongqi
收藏  |  浏览/下载:32/0  |  提交时间:2017/12/06
Identification of novel small-molecule inhibitors targeting menin-MLL interaction, repurposing the antidiarrheal loperamide 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2016, 卷号: 14, 期号: 36, 页码: 8503-8519
作者:  Yue, Liyan;  Du, Juanjuan;  Ye, Fei;  Chen, Zhifeng;  Li, Lianchun
收藏  |  浏览/下载:26/0  |  提交时间:2019/01/08
人LDHA原核表达、纯化及体外抑制剂筛选模型的建立 期刊论文
2015
金科华; 吴昕瑞; 王苗苗; 宋思扬
收藏  |  浏览/下载:3/0  |  提交时间:2016/05/17
SOMG-833, a Novel Selective c-MET Inhibitor, Blocks c-MET-Dependent Neoplastic Effects and Exerts Antitumor Activity 期刊论文
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2014, 卷号: 350, 期号: 1, 页码: 36-45
作者:  Zhang, Hao-tian;  Wang, Lu;  Ai, Jing;  Chen, Yi;  He, Chang-xi
收藏  |  浏览/下载:8/0  |  提交时间:2019/01/08
Approaches for Identification of HIV-1 Entry Inhibitors Targeting gp41 Pocket 期刊论文
VIRUSES-BASEL, 2013, 卷号: 5, 期号: 1
作者:  Yu, Fei;  Lu, Lu;  Du, Lanying;  Zhu, Xiaojie;  Debnath, Asim K.
收藏  |  浏览/下载:2/0  |  提交时间:2019/12/19
Small molecule fusion inhibitors: Design, synthesis and biological evaluation of (Z)-3-(5-(3-benzyl-4-oxo-2-thioxothiazolidinylidene)methyl)-N-(3-carboxy-4-hydroxy)phenyl-2,5-dimethylpyrroles and related derivatives targeting HIV-1 gp41 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2013, 卷号: 21, 期号: 23
作者:  He, Xiao-Yang;  Lu, Lu;  Qiu, Jiayin;  Zou, Peng;  Yu, Fei
收藏  |  浏览/下载:6/0  |  提交时间:2019/12/19
Design, Synthesis, and Biological Evaluation of Highly Potent Small Molecule-Peptide Conjugates as New HIV-1 Fusion Inhibitors 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 56, 期号: 6
作者:  Wang, Chao;  Shi, Weiguo;  Cai, Lifeng;  Lu, Lu;  Wang, Qian
收藏  |  浏览/下载:6/0  |  提交时间:2019/12/19
Establish of Molecular-based High-throughput Screening Model for HDAC6 Inhibitors 期刊论文
Biotechnology Bulletin, 2012, 期号: 8, 页码: 181-188
作者:  Zhang Yue;  Su Mingbo;  Zhou Yubo
收藏  |  浏览/下载:15/0  |  提交时间:2019/01/08
Design, synthesis and biological evaluation of 3-substituted 2,5-dimethyl-N-(3-(1H-tetrazol-5-yl)phenyl)pyrroles as novel potential HIV-1 gp41 inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2011, 卷号: 19, 期号: 22
作者:  He, Xiao-Yang;  Zou, Peng;  Qiu, Jiayin;  Hou, Ling;  Jiang, Shibo
收藏  |  浏览/下载:2/0  |  提交时间:2019/12/19


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