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上海药物研究所 [6]
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北京航空航天大学 [1]
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期刊论文 [21]
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Synthesis and Biological Evaluation of Oxopyrido[2,3-d] Pyrimidine-7-ones Derivatives as Covalent L85812/T790M Mutant Selective Epidermal Growth Factor Receptor (EGFR) Inhibitors
期刊论文
LETTERS IN DRUG DESIGN & DISCOVERY, 2019, 卷号: 16, 期号: 8, 页码: 826-834
作者:
Niu, Ao
;
Wang, Yang
;
Yang, Yushe
;
Wei, Jianhai
;
Ding, Jian
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/07/01
Non-small cell lung cancer
irreversible inhibitors
EGFR(T79014)( )mutant
anti-tumor
xenograft model
cell proliferation
Design, synthesis and anti leukemia cells proliferation activities of pyrimidylaminoquinoline derivatives as DOT1L inhibitors
期刊论文
BIOORGANIC CHEMISTRY, 2018, 卷号: 80, 页码: 649-654
作者:
Zhang, Li
;
Chen, Yantao
;
Liu, Na
;
Li, Linjuan
;
Xiao, Senhao
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  |  
浏览/下载:38/0
  |  
提交时间:2019/01/08
Pyrimidylaminoquinoline
Nonnucleoside DOT1L inhibitors
Amino side chains
Mixed-linage leukemia
Histone lysine methyltransferase
Imidazolium-Based Ionic Liquids Affect Morphology and Rigidity of Living Cells: An Atomic Force Microscopy Study
期刊论文
LANGMUIR, 2018
作者:
Galluzzi, Massimiliano
;
Podesta, Alessandro
;
Milani, Paolo
;
Schulte, Carsten
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  |  
浏览/下载:39/0
  |  
提交时间:2019/01/31
Synthesis and structure–activity relationship studies of MI-2 analogues as MALT1 inhibitors
期刊论文
Bioorganic & Medicinal Chemistry, 2018, 期号: 26, 页码: 3321–3344
作者:
Ceshi Chen
;
Rong Liu
;
Jia Zhou
;
Guolin Wu
;
Haijun Chen
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  |  
浏览/下载:36/0
  |  
提交时间:2018/09/28
Malt1
Mi-2 Analogues
Structure–activity Relationships
Cancer Therapeutics
Subtle Side-Chain Engineering of Random Terpolymers for High-Performance Organic Solar Cells
期刊论文
CHEMISTRY OF MATERIALS, 2018, 卷号: 30, 页码: 3294-3300
作者:
Huo, Lijun
;
Xue, Xiaonan
;
Liu, Tao
;
Xiong, Wentao
;
Qi, Feng
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  |  
浏览/下载:2/0
  |  
提交时间:2019/12/30
Cell engineering
Chains
Conjugated polymers
Fullerenes
Organic solar cells
Alkyl side chains
Design strategies
Morphological properties
Photovoltaic performance
Regioregularity
Side chain modifications
Side-chains
Solar cells
Design, synthesis and antibacterial activity of novel pleuromutilin derivatives with 4H-pyran-4-one and pyridin-4-one substitution in the C-14 side chain
期刊论文
CHINESE CHEMICAL LETTERS, 2016, 卷号: 27, 期号: 2, 页码: 235-240
作者:
Ling, Chen-Yu
;
Tao, Yun-Liang
;
Chu, Wen-Jing
;
Wang, Hui
;
Wang, Hai-Dong
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  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
Multi-drug resistant bacteria
Pleuromutilin
4H-Pyran-4-one
Antibacterial activity
Deletion of the side chain assembly reveals diverse post-PKS modifications in the biosynthesis of ansatrienins
期刊论文
RSC ADVANCES, 2016, 卷号: 6, 期号: 91, 页码: 88571-88579
作者:
Li, Xiaomei
;
Zhu, Jing
;
Shi, Guoyin
;
Sun, Mingwei
;
Guo, Zhixing
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  |  
浏览/下载:6/0
  |  
提交时间:2019/12/17
designsynthesisandantibacterialactivityofnovelpleuromutilinderivativeswith4hpyran4oneandpyridin4onesubstitutioninthec14sidechain
期刊论文
chinesechemicalletters, 2016, 卷号: 27, 期号: 2, 页码: 235
作者:
Ling Chenyu
;
Tao Yunliang
;
Chu Wenjing
;
Wang Hui
;
Wang Haidong
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2020/07/01
INFECTIOUS-DISEASES SOCIETY
AMERICA
AGENTS
Multi-drug resistant bacteria
Pleuromutilin
4H-Pyran-4-one
Antibacterial activity
Synthesis and structure-activity relationship studies of novel [6,6,5] tricyclic oxazolidinone derivatives as potential antibacterial agents
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2015, 卷号: 25, 期号: 10, 页码: 2203-2210
作者:
Xue, Tao
;
Ding, Shi
;
Guo, Bin
;
Chu, Wenjing
;
Wang, Hui
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  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
[6,6,5] tricyclic core structure
Structure-activity relationship
Antibacterial activity
Liver microsomal stability
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