CORC

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CORC

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Potent and Selective RIPK1 Inhibitors Targeting Dual-Pockets for the Treatment of Systemic Inflammatory Response Syndrome and Sepsis 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 页码: 6
作者:  Yang, Xiangbo;  Lu, Huimin;  Xie, Hang;  Zhang, Binbin;  Nie, Tianqing
收藏  |  浏览/下载：24/0  |  提交时间：2022/01/18
Recent Progress and Clinical Development of Inhibitors that Block MDM4/p53 Protein-Protein Interactions 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 15, 页码: 10621-10640
作者:  Zhang, Shiyan;  Lou, Jianfeng;  Li, Yafang;  Zhou, Feilong;  Yan, Ziqin
收藏  |  浏览/下载：63/0  |  提交时间：2021/11/04
A novel tricyclic BTK inhibitor suppresses B cell responses and osteoclastic bone erosion in rheumatoid arthritis 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 12
作者:  Liu, Yu-ting;  Ding, Hui-hua;  Lin, Ze-min;  Wang, Que;  Chen, Li
收藏  |  浏览/下载：24/0  |  提交时间：2021/05/24
Discovery of selective HDAC/BRD4 dual inhibitors as epigenetic probes 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 209, 页码: 20
作者:  Chen, Jingjing;  Li, Yalei;  Zhang, Jie;  Zhang, Minmin;  Wei, Aihuan
收藏  |  浏览/下载：25/0  |  提交时间：2021/05/24
The novel cereblon modulator CC-885 inhibits mitophagy via selective degradation of BNIP3L 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:  Hao, Bing-bing;  Li, Xiao-jing;  Jia, Xing-long;  Wang, Yu-xing;  Zhai, Lin-hui
收藏  |  浏览/下载：45/0  |  提交时间：2020/07/01
Recent advances in dopaminergic strategies for the treatment of Parkinson's disease 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 12
作者:  Mao, Qi;  Qin, Wang-zhi;  Zhang, Ao;  Ye, Na
收藏  |  浏览/下载：27/0  |  提交时间：2020/07/01
Design, synthesis and biological evaluation of 6-deoxy O-spiroketal C-arylglucosides as novel renal sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the treatment of type 2 diabetes 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 180, 页码: 398-416
作者:  Wang, Yibing;  Lou, Yang;  Wang, Jiang;  Li, Dan;  Chen, Hui
收藏  |  浏览/下载：18/0  |  提交时间：2020/07/01
Identification of new dual FABP4/5 inhibitors based on a naphthalene-1-sulfonamide FABP4 inhibitor 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 19, 页码: 16
作者:  He, Yulong;  Dou, Huixia;  Gao, Dingding;  Wang, Ting;  Zhang, Mingming
收藏  |  浏览/下载：17/0  |  提交时间：2020/07/01
Preclinical evaluation of 3D185, a novel potent inhibitor of FGFR1/2/3 and CSF-1R, in FGFR-dependent and macrophage-dominant cancer models 期刊论文
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2019, 卷号: 38, 期号: 1, 页码: 16
作者:  Peng, Xia;  Hou, Pengcong;  Chen, Yi;  Dai, Yang;  Ji, Yinchun
收藏  |  浏览/下载：6/0  |  提交时间：2020/07/01
Design and Synthesis of Potent, Selective Inhibitors of Protein Arginine Methyltransferase 4 against Acute Myeloid Leukemia 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 11, 页码: 5414-5433
作者:  Guo, Zuhao;  Zhang, Zhuqing;  Yang, Hong;  Cao, Danyan;  Xu, Xiaowei
收藏  |  浏览/下载：16/0  |  提交时间：2020/07/01

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