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Furmonertinib (Alflutinib, AST2818) is a potential positive control drug comparable to rifampin for evaluation of CYP3A4 induction in sandwich-cultured primary human hepatocytes 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10
作者:  Wu, Ya-li;  Xue, Ya-ru;  Guo, Zi-tao;  Chen, Zhen-dong;  Ge, Xin-yu
收藏  |  浏览/下载:22/0  |  提交时间:2021/08/17
Functional Proliferating Human Hepatocytes: In Vitro Hepatocyte Model for Drug Metabolism, Excretion, and Toxicity 期刊论文
DRUG METABOLISM AND DISPOSITION, 2021, 卷号: 49, 期号: 4, 页码: 305-313
作者:  Qiao, Shida;  Feng, Sisi;  Wu, Zhitao;  He, Ting;  Ma, Chen
收藏  |  浏览/下载:26/0  |  提交时间:2021/05/24
18 beta-Glycyrrhetinic acid protects against alpha-naphthylisothiocyanate-induced cholestasis through activation of the Sirt1/FXR signaling pathway 期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 12, 页码: 1865-1873
作者:  Wu, Shou-yan;  Cui, Shi-chao;  Wang, Le;  Zhang, Yi-ying;  Yan, Xiao-xia
收藏  |  浏览/下载:13/0  |  提交时间:2020/07/01
The involvement of multidrug and toxin extrusion protein 1 in the distribution and excretion of berberine 期刊论文
XENOBIOTICA, 2018, 卷号: 48, 期号: 3, 页码: 314-323
作者:  Xiao, Ling;  Xue, Yaru;  Zhang, Cuifeng;  Wang, Le;  Lin, Yunfei
收藏  |  浏览/下载:38/0  |  提交时间:2019/01/08
Nimesulide and 4 '-Hydroxynimesulide as Bile Acid Transporters Inhibitors Are Contributory Factors for Drug-Induced Cholestasis 期刊论文
DRUG METABOLISM AND DISPOSITION, 2017, 卷号: 45, 期号: 5, 页码: 441-448
作者:  Zhou, Lei;  Pang, Xiaoyan;  Jiang, Jingfang;  Zhong, Dafang;  Chen, Xiaoyan
收藏  |  浏览/下载:17/0  |  提交时间:2019/01/08
Optimized Hepatocyte-Like Cells with Functional Drug Transporters Directly-Reprogrammed from Mouse Fibroblasts and their Potential in Drug Disposition and Toxicology 期刊论文
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 2016, 卷号: 38, 期号: 5, 页码: 1815-1830
作者:  Wu, Zhi-Tao;  Yao, Dan;  Ji, Shu-Yi;  Ni, Xuan;  Gao, Yi-Meng
收藏  |  浏览/下载:28/0  |  提交时间:2019/01/08
Fasiglifam (TAK-875) Inhibits Hepatobiliary Transporters: A Possible Factor Contributing to Fasiglifam-Induced Liver Injury 期刊论文
Drug metabolism and disposition: the biological fate of chemicals, 2015, 卷号: 43, 期号: 11, 页码: 1751-9
作者:  Li, Xiuli;  Zhong, Kan;  Guo, Zitao;  Zhong, Dafang;  Chen, Xiaoyan
收藏  |  浏览/下载:35/0  |  提交时间:2019/01/08
The Hepatobiliary Disposition of Timosaponin B2 Is Highly Dependent on Influx/Efflux Transporters but Not Metabolism 期刊论文
DRUG METABOLISM AND DISPOSITION, 2015, 卷号: 43, 期号: 1, 页码: 63-72
作者:  Sheng, Jingjing;  Tian, Xiaoting;  Xu, Guanglin;  Wu, Zhitao;  Chen, Chen
收藏  |  浏览/下载:7/0  |  提交时间:2019/01/08
Timosaponin A3 induces hepatotoxicity in rats through inducing oxidative stress and down-regulating bile acid transporters 期刊论文
ACTA PHARMACOLOGICA SINICA, 2014, 卷号: 35, 期号: 9, 页码: 1188-1198
作者:  Wu, Zhi-tao;  Qi, Xin-ming;  Sheng, Jing-jing;  Ma, Lei-lei;  Ni, Xuan
收藏  |  浏览/下载:20/0  |  提交时间:2019/01/08
Opposite regulation of hepatic breast cancer resistance protein in type 1 and 2 diabetes mellitus 期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2014, 卷号: 724, 页码: 185-192
作者:  He, Lei;  Yang, Yuan;  Guo, Cen;  Yao, Dan;  Liu, Hui-hui
收藏  |  浏览/下载:15/0  |  提交时间:2019/01/08


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