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上海药物研究所 [74]
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E3 ubiquitin ligase NEDD4L negatively regulates inflammation by promoting ubiquitination of MEKK2
期刊论文
EMBO REPORTS, 2022
作者:
Li, Hui
;
Wang, Ning
;
Jiang, Yu
;
Wang, Haofei
;
Xin, Zengfeng
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2022/12/22
IL-17R signaling
inflammation
MEKK2
NEDD4L
ubiquitination
Expert consensus on the diagnosis and treatment of NTRK gene fusion solid tumors in China
期刊论文
THORACIC CANCER, 2022
作者:
Xu, Chunwei
;
Si, Lu
;
Wang, Wenxian
;
Li, Ziming
;
Song, Zhengbo
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2022/12/22
fusion
precision medicine
solid tumor
targeted therapy
tyrosine receptor kinase
Sugemalimab vs Placebo after cCRT or sCRT in pts with Unresectable Stage III NSCLC: Final PFS Analysis of a Phase 3 Study
期刊论文
JOURNAL OF THORACIC ONCOLOGY, 2022, 卷号: 17
作者:
Wu, Y. -L.
;
Zhou, Q.
;
Chen, M.
;
Pan, Y.
;
Jian, O.
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/12/23
CCRT
sCRT
PD-L1 inhibitor
Cucumber (Cucumis sativus L.) Leaf Extract as a Green Corrosion Inhibitor for Carbon Steel in Acidic Solution: Electrochemical, Functional and Molecular Analysis
期刊论文
MOLECULES, 2022, 卷号: 27, 期号: 12, 页码: 18
作者:
Feng, Lijuan
;
Zhang, Shanshan
;
Hao, Long
;
Du, Hongchen
;
Pan, Rongkai
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2022/09/16
carbon steel
extract
green corrosion inhibitor
quantum chemical calculation
Systemic Therapy for Hepatocellular Carcinoma: Chinese Consensus-Based Interdisciplinary Expert Statements
期刊论文
LIVER CANCER, 2022, 卷号: 11
作者:
Sun, Yongkun
;
Zhang, Wen
;
Bi, Xinyu
;
Yang, Zhengqiang
;
Tang, Yu
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2022/12/23
Chinese interdisciplinary experts
Hepatocellular carcinoma
Molecular targeted therapy
Consensus
Pamiparib Monotherapy for Patients with Germline BRCA1/2-Mutated Ovarian Cancer Previously Treated with at Least Two Lines of Chemotherapy: A Multicenter, Open-Label, Phase II Study
期刊论文
CLINICAL CANCER RESEARCH, 2022, 卷号: 28
作者:
Wu, Xiaohua
;
Zhu, Jianqing
;
Wang, Jing
;
Lin, Zhongqiu
;
Yin, Rutie
收藏
  |  
浏览/下载:103/0
  |  
提交时间:2022/03/28
Pharmacodynamic, pharmacokinetic, and phase 1a study of bisthianostat, a novel histone deacetylase inhibitor, for the treatment of relapsed or refractory multiple myeloma
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Zhou, Yu-bo
;
Zhang, Yang-ming
;
Huang, Hong-hui
;
Shen, Li-jing
;
Han, Xiao-feng
收藏
  |  
浏览/下载:93/0
  |  
提交时间:2021/11/04
multiple myeloma
HDAC inhibitor
bisthianostat
pharmacodynamics
pharmacokinetics
phase 1a clinical trial
antitumor drug
Global identification of phospho-dependent SCF substrates reveals a FBXO22 phosphodegron and an ERK-FBXO22-BAG3 axis in tumorigenesis
期刊论文
CELL DEATH AND DIFFERENTIATION, 2021, 页码: 13
作者:
Liu, Ping
;
Cong, Xiaoji
;
Liao, Shengjie
;
Jia, Xinglong
;
Wang, Xiaomin
收藏
  |  
浏览/下载:78/0
  |  
提交时间:2021/08/17
The ZMYND8-regulated mevalonate pathway endows YAP-high intestinal cancer with metabolic vulnerability
期刊论文
MOLECULAR CELL, 2021, 卷号: 81, 期号: 13, 页码: 2736-+
作者:
Pan, Qiang
;
Zhong, Shanshan
;
Wang, Hanling
;
Wang, Xuege
;
Li, Ni
收藏
  |  
浏览/下载:74/0
  |  
提交时间:2021/11/04
SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target
期刊论文
CELL RESEARCH, 2021, 页码: 14
作者:
Xia, Bingqing
;
Shen, Xurui
;
He, Yang
;
Pan, Xiaoyan
;
Liu, Feng-Liang
收藏
  |  
浏览/下载:78/0
  |  
提交时间:2021/08/17
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