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上海药物研究所 [73]
大连化学物理研究所 [13]
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厦门大学 [11]
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期刊论文 [207]
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Synthesis and biological evaluation of 2,5-diaryl-1,3,4-oxadiazole derivatives as novel Src homology 2 domain-containing protein tyrosine phosphatase 2 (SHP2) inhibitors
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 13
作者:
Meng, Xiang-Dong
;
Gao, Li-Xin
;
Wang, Zhi-Jia
;
Feng, Bo
;
Zhang, Chun
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2021/12/01
2,5-diphenyl-1,3,4-oxadiazole derivatives
SHP2
Inhibitors
Structure-activity relationships (SAR)
Structural insights into ligand recognition and activation of the melanocortin-4 receptor
期刊论文
CELL RESEARCH, 2021, 页码: 13
作者:
Zhang, Huibing
;
Chen, Li-Nan
;
Yang, Dehua
;
Mao, Chunyou
;
Shen, Qingya
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  |  
浏览/下载:34/0
  |  
提交时间:2021/11/04
Silver nanoparticles protect against arsenic induced genotoxicity via attenuating arsenic bioaccumulation and elevating antioxidation in mammalian cells
期刊论文
JOURNAL OF HAZARDOUS MATERIALS, 2021, 卷号: 413
作者:
Wang, Xue
;
Nie, Yaguang
;
Si, Bo
;
Wang, Tong
;
Hei, Tom K.
收藏
  |  
浏览/下载:94/0
  |  
提交时间:2021/06/15
Arsenic (As)
Silver nanoparticles (AgNPs)
Detoxification
Bioaccumulation
Antioxidation
Aggregate binding agents improve soil aggregate stability in Robinia pseudoacacia forests along a climatic gradient on the Loess Plateau, China
期刊论文
JOURNAL OF ARID LAND, 2021, 卷号: 13, 期号: 2, 页码: 165-174
作者:
Jing, Hang
;
Meng, Min
;
Wang, Guoliang
;
Liu, Guobin
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2021/06/10
binding agents
glomalin
organic carbon
soil property
soil aggregate stability
Identification and characterization of Gd-binding proteins in NIH-3T3 cells
期刊论文
TALANTA, 2020, 卷号: 219, 页码: 1-8
作者:
Nong, Qiying
;
Chen, Xi
;
Hu, Ligang
;
Huang, Yongshun
;
Luan, Tiangang
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2021/09/14
Gadolinium
Gadolinium-based contrast agents
Gd-binding protein
NIH-3T3 cell
Tubulin
Toxicity
Pharmacological characterization of mono-, dual- and tri-peptidic agonists at GIP and GLP-1 receptors
期刊论文
BIOCHEMICAL PHARMACOLOGY, 2020, 卷号: 177, 页码: 13
作者:
Yuliantie, Elita
;
Darbalaei, Sanaz
;
Dai, Antao
;
Zhao, Peishen
;
Yang, Dehua
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/12/24
G protein-coupled receptor
Glucose-dependent insulinotropic peptide receptor
Glucagon-like peptide-1 receptor
Biased agonist
GPCR signaling
Discovery of New and Potent InhA Inhibitors as Antituberculosis Agents: Structure-Based Virtual Screening Validated by Biological Assays and X-ray Crystallography
期刊论文
JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2020, 卷号: 60, 期号: 1, 页码: 226-234
作者:
Kamsri, Pharit
;
Hanwarinroj, Chayanin
;
Phusi, Naruedon
;
Pornprom, Thimpika
;
Chayajarus, Kampanart
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  |  
浏览/下载:24/0
  |  
提交时间:2020/07/01
Discovery of betulinaldehyde as a natural ROR gamma t agonist
期刊论文
FITOTERAPIA, 2019, 卷号: 137, 页码: 8
作者:
Yang, Feng
;
Zhang, Ruihan
;
Ni, Dongxuan
;
Luo, Xiaomin
;
Chen, Shijie
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2020/07/01
ROR gamma t
Receptor agonist
Triterpenoids
Alpha screen
Molecular docking
Synthesis and biological evaluation of tryptophan-derived rhodanine derivatives as PTP1B inhibitors and anti-bacterial agents
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 172, 页码: 163-173
作者:
Liu, Hongyan
;
Sun, Danwen
;
Du, Hang
;
Zheng, Changji
;
Li, Jingya
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2020/07/01
Tryptophan-derived rhodanine
PTP1B inhibitor
Anti-bacterial
SAR
Identification of a New alpha-Synuclein Aggregation Inhibitor via Mass Spectrometry Based Screening
期刊论文
ACS CHEMICAL NEUROSCIENCE, 2019, 卷号: 10, 期号: 6, 页码: 2683-2691
作者:
Xu, Mingming
;
Loa-Kum-Cheung, Wendy
;
Zhang, Haiyan
;
Quinn, Ronald J.
;
Mellick, George D.
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2020/07/01
Parkinson's disease
alpha-synuclein
aggregation
mass spectrometry
screening
inhibitor
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