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武汉大学 [10]
上海药物研究所 [8]
复旦大学上海医学院 [6]
上海生物化学与细胞生... [6]
南华大学 [5]
山东大学 [3]
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期刊论文 [60]
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Discovery of a novel protein kinase C activator from Croton tiglium for inhibition of non-small cell lung cancer
期刊论文
PHYTOMEDICINE, 2019, 卷号: 65, 页码: 11
作者:
Wang Yuwei
;
Tang Chunping
;
Yao Sheng
;
Lai Huanling
;
Li Runze
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2020/07/01
Non-small cell lung cancer
Natural product
Croton tiglium
Protein kinase C
Molecular modelling
Discovery of N-(4-(6-Acetamidopyrimidin-4-yloxy)phenyl)-2-(2-(trifluoromethyl)phenyl)acetamide (CHMFL-FLT3-335) as a Potent FMS-like Tyrosine Kinase 3 Internal Tandem Duplication (FLT3-ITD) Mutant Selective Inhibitor for Acute Myeloid Leukemia
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 2, 页码: 875-892
作者:
Liang, Xiaofei
;
Wang, Beilei
;
Chen, Cheng
;
Wang, Aoli
;
Hu, Chen
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  |  
浏览/下载:19/0
  |  
提交时间:2020/05/21
The short interference RNA (siRNA) targeting NMUR2 relieves nociception in a bone cancer pain model of rat through PKC-ERK and PI3K-AKT pathways
期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2019, 卷号: 512, 期号: 3
作者:
Zhang, Yu
;
Liu, Shasha
;
Wang, Jing
;
Peng, Sheng
;
Lu, Yingjun
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  |  
浏览/下载:23/0
  |  
提交时间:2019/12/05
Bone cancer pain
Neuromedin U receptor 2
Interfering RNA
PKC/ERK
PI3K/AKT
The short interference RNA (siRNA) targeting NMUR2 relieves nociception in a bone cancer pain model of rat through PKC-ERK and PI3K-AKT pathways
期刊论文
Biochemical and biophysical research communications, 2019
作者:
Peng Sheng[1]
;
Lu Yingjun[2]
;
Li Pengyi[3]
;
Liu Peirong[4]
;
Shi Xiaowei[5]
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  |  
浏览/下载:6/0
  |  
提交时间:2019/04/22
Bone cancer pain
Interfering RNA
Neuromedin U receptor 2
PI3K/AKT
PKC/ERK
Baicalein and baicalin alleviate acetaminophen-induced liver injury by activating Nrf2 antioxidative pathway: The involvement of ERK1/2 and PKC
期刊论文
Biochemical pharmacology, 2018, 卷号: 150, 页码: 9-23
作者:
Shi, Liang
;
Hao, Zhanxia
;
Zhang, Shaobo
;
Wei, Mengjuan
;
Lu, Bin
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
Sr-doped nanowire modification of Ca-Si-based coatings for improved osteogenic activities and reduced inflammatory reactions
期刊论文
NANOTECHNOLOGY, 2018, 卷号: 29, 期号: 8
作者:
Li, Kai
;
Hu, Dandan
;
Xie, Youtao
;
Huang, Liping
;
Zheng, Xuebin
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2018/12/28
Ca-Si coatings
nanowire-like topography
Sr dopant
osteogenic activities
inflammatory reactions
Silencing the ACAT1 Gene in Human SH-SY5Y Neuroblastoma Cells Inhibits the Expression of Cyclo-Oxygenase 2 (COX2) and Reduces beta-Amyloid-Induced Toxicity Due to Activation of Protein Kinase C (PKC) and ERK
期刊论文
MEDICAL SCIENCE MONITOR, 2018, 卷号: 24
作者:
Chen, Ying
;
Zhu, Lu
;
Ji, Lei
;
Yang, Ying
;
Lu, Lu
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/05
Acyl-coenzymeA: Cholesterol Acyltransferase
Alzheimer Disease
Cyclooxygenase 2
Baicalein and baicalin alleviate acetaminophen-induced liver injury by activating Nrf2 antioxidative pathway: The involvement of ERK1/2 and PKC
期刊论文
BIOCHEMICAL PHARMACOLOGY, 2018, 卷号: 150
作者:
Shi, Liang
;
Hao, Zhanxia
;
Zhang, Shaobo
;
Wei, Mengjuan
;
Lu, Bin
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/05
Baicalin
Hepato-protection
Nrf2
ERK1/2
PKC
Vibsanin A sensitizes human acute myeloid leukemia cells to tyrosine kinase inhibitor-induced myeloid differentiation via activation of PKC and upregulation of Lyn
期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, 卷号: 502, 期号: 1, 页码: 110-115
作者:
Shen, Xing
;
Xing, Shuang
;
Zhang, Lu
;
Wang, Fangmin
;
Ou, Hongling
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  |  
浏览/下载:55/0
  |  
提交时间:2019/03/29
Ketamine-induced neurotoxicity blocked by N-Methyl-D-aspartate is mediated through activation of PKC/ERK pathway in developing hippocampal neurons.
期刊论文
Neurosci Lett, 2018
作者:
Jiang S
;
Li X
;
Jin W
;
Duan X
;
Bo L
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/03/26
Hippocampus
Ketamine
NMDA
PKC/ERK
signaling
pathway
cell
cycle
re-entry
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