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CORC

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Cryo-EM structures of PI3K alpha reveal conformational changes during inhibition and activation 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 45, 页码: 9
作者:  Liu, Xiao;  Yang, Su;  Hart, Jonathan R.;  Xu, Yingna;  Zou, Xinyu
收藏  |  浏览/下载：39/0  |  提交时间：2022/01/04
The genomic landscape of young and old lung cancer patients highlights age-dependent mutation frequencies and clinical actionability in young patients 期刊论文
INTERNATIONAL JOURNAL OF CANCER, 2021
作者:  Cai, Lei;  Chen, Yong;  Tong, Xiaoling;  Wu, Xue;  Bao, Hua
收藏  |  浏览/下载：63/0  |  提交时间：2021/06/15
Immune microenvironment features and efficacy of PD-1/PD-L1 blockade in non-small cell lung cancer patients with EGFR or HER2 exon 20 insertions 期刊论文
THORACIC CANCER, 2020
作者:  Chen, Kaiyan;  Pan, Guoqiang;  Cheng, Guoping;  Zhang, Fanrong;  Xu, Yanjun
收藏  |  浏览/下载：39/0  |  提交时间：2020/12/28
EGFR  HER2  immunotherapy  NSCLC  PD‐  L1  
Distinct co-acquired alterations and genomic evolution during TKI treatment in non-small-cell lung cancer patients with or without acquired T790M mutation 期刊论文
ONCOGENE, 2020, 卷号: 39
作者:  Jin, Ying;  Bao, Hua;  Le, Xiuning;  Fan, Xiaojun;  Tang, Ming
收藏  |  浏览/下载：26/0  |  提交时间：2020/11/26
Membrane metallo-endopeptidase mediates cellular senescence induced by oncogenic PIK3CA(H1047R) accompanied with pro-tumorigenic secretome 期刊论文
INTERNATIONAL JOURNAL OF CANCER, 2019, 卷号: 145, 期号: 3, 页码: 817-829
作者:  Liu, Xue-Ling;  Liu, Jia-Li;  Xu, Yi-Chao;  Zhang, Xi;  Wang, Yu-Xiang
收藏  |  浏览/下载：14/0  |  提交时间：2020/07/01
The distinct clinicopathological and prognostic implications of PIK3CA mutations in breast cancer patients from Central China 期刊论文
CANCER MANAGEMENT AND RESEARCH, 2019, 卷号: 11, 页码: 1473-1492
作者:  Lin, Wenchu;  Wu, Haibo;  Wang, Wei;  Du, Jun;  Li, Hong
收藏  |  浏览/下载：45/0  |  提交时间：2019/06/20
High-throughput barcode screening elucidates the functional characteristics and mutual relevance of PIK3CA and PIK3R1 somatic mutations in Chinese patients with breast cancer 会议论文
作者:  Chen, L.;  Yang, L.;  Hu, X.;  Shao, Z.
收藏  |  浏览/下载：5/0  |  提交时间：2019/12/05
The distinct clinicopathological and prognostic implications of pik3ca mutations in breast cancer patients from central china 期刊论文
Cancer management and research, 2019, 卷号: 11, 页码: 1473-1492
作者:  Wu, Haibo;  Wang, Wei;  Du, Jun;  Li, Hong;  Wang, Huogang
收藏  |  浏览/下载：58/0  |  提交时间：2019/05/08
The distinct clinicopathological and prognostic implications of PIK3CA mutations in breast cancer patients from Central China 期刊论文
CANCER MANAGEMENT AND RESEARCH, 2019, 卷号: 11, 期号: 无, 页码: 1473-1492
作者:  Wu, Haibo;  Wang, Wei;  Du, Jun;  Li, Hong;  Wang, Huogang
收藏  |  浏览/下载：4/0  |  提交时间：2020/05/21
Synthesis, biological evaluation and structure-activity relationship of a novel class of PI3K alpha H1047R mutant inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 158, 页码: 707-719
作者:  Zhang, Ning;  Yu, Zhimei;  Yang, Xiaohong;  Zhou, Yan;  Wang, Jia
收藏  |  浏览/下载：85/0  |  提交时间：2019/01/08

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