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大连化学物理研究所 [8]
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Furmonertinib (Alflutinib, AST2818) is a potential positive control drug comparable to rifampin for evaluation of CYP3A4 induction in sandwich-cultured primary human hepatocytes
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10
作者:
Wu, Ya-li
;
Xue, Ya-ru
;
Guo, Zi-tao
;
Chen, Zhen-dong
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/08/17
furmonertinib (alflutinib
AST2818)
quantitative proteomics
sandwich-cultured human hepatocytes
Nitrogen-doped graphene quantum dots (N-GQDs) perturb redox-sensitive system via the selective inhibition of antioxidant enzyme activities in zebrafish
期刊论文
BIOMATERIALS, 2019, 卷号: 206, 页码: 61-72
作者:
Deng, Shun
;
Fu, Ailing
;
Junaid, Muhammad
;
Wang, Yan
;
Yin, Qian
收藏
  |  
浏览/下载:65/0
  |  
提交时间:2019/06/11
Danio rerio
N-GQDs
Redox system
Antioxidant enzyme activity
USGO
Metabolic profiling of dehydrodiisoeugenol using xenobiotic metabolomics
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2017, 卷号: 145, 页码: 725-733
作者:
Lv, Qian-Qian
;
Yang, Xiao-Nan
;
Yan, Dong-Mei
;
Liang, Wei-Qing
;
Liu, Hong-Ning
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2017/10/23
Dehydrodiisoeugenol
Xenobiotic Metabolomics
Metabolic Profiling
Uplc-esi-qtofms
Toxic responses of cytochrome P450 sub-enzyme activities to heavy metals exposure in soil and correlation with their bioaccumulation in Eisenia fetida
期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2017, 页码: 158-165
作者:
Cao, Xiufeng
;
Bi, Ran
;
Song, Yufang
收藏
  |  
浏览/下载:229/0
  |  
提交时间:2018/09/10
Biomarker
Heavy metal
Eco-toxicity
Soil
Bioavailability
In vitro oxidative decarboxylation of free fatty acids to terminal alkenes by two new P450 peroxygenases
期刊论文
BIOTECHNOLOGY FOR BIOFUELS, 2017, 卷号: 10
作者:
Xu, Huifang
;
Ning, Linlin
;
Yang, Wenxia
;
Fang, Bo
;
Wang, Cong
收藏
  |  
浏览/下载:107/0
  |  
提交时间:2017/12/04
Alkenes
Biofuels
P450 Fatty Acid Decarboxylases
Substrate Specificity
Chemoselectivity
Site-directed Mutagenesis
Enzyme Kinetics
Effects of pentachlorophenol on the quail (Coturnix japonica) liver detoxification pathway
期刊论文
CHEMOSPHERE, 2017, 卷号: 177, 期号: 0, 页码: 44-50
作者:
Dai, Jiayin
;
Wei, Dongbing
;
Jiang, Peng
;
Wang, Jianshe
;
Sheng, Nan
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2018/07/26
Pentachlorophenol
Cytochrome P450
Nf-kappa b
Nrf2
Coturnix Japonica
Salvia miltiorrhiza Roots against Cardiovascular Disease: Consideration of Herb-Drug Interactions
期刊论文
BIOMED RESEARCH INTERNATIONAL, 2017
作者:
Chen, Feng
;
Li, Li
;
Tian, Dan-Dan
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  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
Constituents from the Roots of Actinidia chinensis and Their Cytochrome P450 Enzyme Inhibitory Activities
期刊论文
CHEMISTRY & BIODIVERSITY, 2016, 卷号: 13, 期号: 11
作者:
Xu, Yi-Xin
;
Xiang, Zhao-Bao
;
Jin, Yong-Sheng
;
Xu, Wen
;
Sun, Lian-Na
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/06
Actinidia chinensis PLANCH
Actinidiaceae
Triterpenoid
Cytochrome P450 enzyme inhibitory activity
Drug metabolism
Inhibitory effects of sanguinarine on human liver cytochrome P450 enzymes
期刊论文
food and chemical toxicology, 2013, 卷号: 56, 页码: 392-397
作者:
Qi, Xiao-Yi
;
Liang, Si-Cheng
;
Ge, Guang-Bo
;
Liu, Yong
;
Dong, Pei-Pei
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2014/09/11
Sanguinarine
Human liver microsomes
Cytochrome P450 enzyme
Drug-drug interaction
Time-dependent inhibition
Association between Common CYP1A2 Polymorphisms and Theophylline Metabolism in Non-smoking Healthy Volunteers
期刊论文
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2013, 卷号: 112, 期号: 4, 页码: 257-263
作者:
Wang, Liqing
;
Hu, Zheyi
;
Deng, Xun
;
Wang, Yong
;
Zhang, Zhongyi
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/01/08
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