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科研机构
上海药物研究所 [46]
高能物理研究所 [19]
北京大学 [17]
生态环境研究中心 [12]
西北高原生物研究所 [9]
四川大学 [9]
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期刊论文 [222]
会议论文 [4]
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Novel fluorescent GLUT1 inhibitor for precision detection and fluorescence image-guided surgery in oral squamous cell carcinoma
期刊论文
INTERNATIONAL JOURNAL OF CANCER, 2022, 卷号: 151, 期号: 3, 页码: 450-462
作者:
Tian, Yu
;
Tang, Chu
;
Shi, Guangyuan
;
Wang, Guorong
;
Du, Yang
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2022/07/25
fluorescence molecular imaging
glucose transporter type 1
image-guided surgery
mouth neoplasms
WZB117
Health Risks of Chronic Exposure to Small Doses of Microcystins: AnIntegrative Metabolomic and Biochemical Study of Human Serum br
期刊论文
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2022, 卷号: 56, 期号: 10, 页码: 6548-6559
作者:
He, Jun
;
Chen, Jun
;
Chen, Feng
;
Chen, Liang
;
Giesy, John P.
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2022/07/26
metabolomics
microcystin
epidemiological study
health risk
renal injury
Zanubrutinib monotherapy for relapsed or refractory non-germinal center diffuse large B-cell lymphoma
期刊论文
BLOOD ADVANCES, 2022, 卷号: 6
作者:
Yang, Haiyan
;
Xiang, Bing
;
Song, Yuqin
;
Zhang, Huilai
;
Zhao, Weili
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2022/12/23
Nano-selenium attenuates mitochondrial-associated apoptosis via the PI3K/AKT pathway in nickel-induced hepatotoxicity in vivo and in vitro
期刊论文
ENVIRONMENTAL TOXICOLOGY, 2021
作者:
Wang, Caixia
;
Gu, Zhangyu
;
Gu, Xueyan
;
Tan, Xinyue
;
Wang, Shuang
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2021/11/01
hepatotoxicity
mitochondrial apoptosis
Nano-Se
nickel
PI3K-Akt pathway
Metabolic map of the antiviral drug podophyllotoxin provides insights into hepatotoxicity
期刊论文
XENOBIOTICA, 2021, 页码: 13
作者:
Sun, Dongxue
;
Gao, Xiaoxia
;
Wang, Qiao
;
Krausz, Kristopher W.
;
Fang, Zhongze
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  |  
浏览/下载:48/0
  |  
提交时间:2021/11/04
CYP
podophyllotoxin metabolism
liver microsomes
recombinant drug-metabolizing enzymes
hepatic and intestinal toxicity
Simultaneous determination of monocrotaline and its N-oxide metabolite in rat plasma using LC-MS/MS: Application to a pharmacokinetic study
期刊论文
BIOMEDICAL CHROMATOGRAPHY, 2021, 页码: 7
作者:
Lin, Feifei
;
Pan, Anni
;
Ye, Yang
;
Liu, Jia
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2021/08/17
LC-MS
MS
monocrotaline
monocrotaline N-oxide
pharmacokinetics
A phase I study of the safety and activity of K-001 in patients with advanced pancreatic ductal adenocarcinoma
期刊论文
BMC Cancer, 2021, 卷号: 21, 期号: 1
作者:
Cui,Jiujie
;
Yang,Haiyan
;
Liu,Jue
;
Chen,Donghui
;
Hu,Jiong
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  |  
浏览/下载:85/0
  |  
提交时间:2021/06/15
Pancreatic ductal adenocarcinoma
Phase I study
Safety
K-001
Clinical trial
SAF-248, a novel PI3K delta-selective inhibitor, potently suppresses the growth of diffuse large B-cell lymphoma
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:
Zhang, Xi
;
Duan, Yu-ting
;
Wang, Yi
;
Zhao, Xing-dong
;
Sun, Yi-ming
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2021/05/24
PI3Kδ
PI3K
AKT
mTOR
diffuse large B-cell lymphoma
resistance
combination therapy
Effect of dietary vitamins in oral bioaccessibility of lead in contaminated soils based on the physiologically based extraction test
期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2020, 卷号: 747, 页码: 1-10
作者:
Yin, Naiyi
;
Han, Zeliang
;
Du, Huili
;
Wang, Pengfei
;
Li, Yunpeng
收藏
  |  
浏览/下载:80/0
  |  
提交时间:2021/09/15
Soil
Lead
Bioaccessibility
Vitamin
Health risk
Assessment of reactive oxygen species production and genotoxicity of rare earth mining dust: Implications for public health and mining management
期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2020, 卷号: 740, 页码: 10
作者:
Tian, Shuhan
;
Li, Kexin
;
Moller, Peter
;
Ying, Samantha C.
;
Wang, Lingqing
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2021/03/18
Rare earth elements
REE
Mine pollution
Genotoxicity
ROS production
Source apportionment
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