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上海药物研究所 [14]
大连化学物理研究所 [6]
武汉植物园 [1]
武汉大学 [1]
上海生物化学与细胞生... [1]
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期刊论文 [21]
会议论文 [2]
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Synthesis and biological investigation of triazolopyridinone derivatives as potential multireceptor atypical antipsychotics
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 8, 页码: 6
作者:
Shi, Wenqiang
;
Wang, Yu
;
Wu, Chunhui
;
Yang, Feipu
;
Zheng, Wei
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/07/01
Triazolopyridinone
Antipsychotic
Multireceptor
5-HT1A receptor
Structure-Aided Identification and Optimization of Tetrahydro-isoquinolines as Novel PDE4 Inhibitors Leading to Discovery of an Effective Antipsoriasis Agent
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 11, 页码: 5579-5593
作者:
Zhang, Xianglei
;
Dong, Guangyu
;
Li, Heng
;
Chen, Wuyan
;
Li, Jian
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  |  
浏览/下载:14/0
  |  
提交时间:2020/07/01
Positive Allosteric Modulation of AMPAR by PF-4778574 Produced Rapid Onset Antidepressant Actions in Mice
期刊论文
Cerebral cortex (New York, N.Y. : 1991), 2018
作者:
Shen, Mengxin
;
Lv, Dan
;
Li, Shuting
;
Zhang, Yanhua
;
Wang, Zhen
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  |  
浏览/下载:104/0
  |  
提交时间:2019/01/08
Discovery of novel antagonists on (2)-adrenoceptor from natural products using a label-free cell phenotypic assay
期刊论文
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2018, 卷号: 391, 期号: 12, 页码: 1411-1420
作者:
Wang, Anhui
;
Zhang, Pengyu
;
Wang, Jixia
;
Zhao, Ying
;
Zhang, Xiuli
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  |  
浏览/下载:55/0
  |  
提交时间:2019/06/20
beta(2)-Adrenoceptor
Antagonist
Natural product
Label-free cell phenotypic assay
Discovery of novel antagonists on (2)-adrenoceptor from natural products using a label-free cell phenotypic assay
期刊论文
Naunyn-schmiedebergs archives of pharmacology, 2018, 卷号: 391, 期号: 12, 页码: 1411-1420
作者:
Zhang, Pengyu
;
Wang, Jixia
;
Zhao, Ying
;
Zhang, Xiuli
;
Qu, Lala
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  |  
浏览/下载:72/0
  |  
提交时间:2019/05/08
Beta(2)-adrenoceptor
Antagonist
Natural product
Label-free cell phenotypic assay
Discovery of a series of dihydroquinoxalin-2(1H)-ones as selective BET inhibitors from a dual PLK1-BRD4 inhibitor
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 137, 页码: 176-195
作者:
Hu, Jianping
;
Wang, Yingqing
;
Li, Yanlian
;
Xu, Lin
;
Cao, Danyan
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  |  
浏览/下载:32/0
  |  
提交时间:2019/01/08
BRD4 inhibitor
Kinase
BI-2536
Dihydroquinoxalin-2(1H)-one
Activation of D1R/PKA/mTOR signaling cascade in medial prefrontal cortex underlying the antidepressant effects of l-SPD
期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7
作者:
Zhang, Bing
;
Guo, Fei
;
Ma, Yuqin
;
Song, Yingcai
;
Lin, Rong
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  |  
浏览/下载:25/0
  |  
提交时间:2019/01/08
Digital Gene Expression Analysis Provides Insight into the Transcript Profile of the Genes Involved in Aporphine Alkaloid Biosynthesis in Lotus (Nelumbo nucifera)
期刊论文
Frontiers in Plant Science, 2017, 卷号: 8, 页码: 19
作者:
Yang, Mei
;
Zhu, Lingping
;
Li, Ling
;
Li, Juanjuan
;
Xu, Liming
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2017/12/31
lotus
aporphine alkaloids
co-expression network
biosynthesis
putative genes
Fragmentation patterns study of iridoid glycosides in Fructus Gardeniae by HPLC-Q/TOF-MS/MS
期刊论文
BIOMEDICAL CHROMATOGRAPHY, 2014, 卷号: 28, 期号: 12, 页码: 1795-1807
作者:
Fu, Zhiwen
;
Xue, Rui
;
Li, Zhixiong
;
Chen, Mingcang
;
Sun, Zhaolin
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
Fragmentation patterns
iridoid glycosides
Fructus Gardeniae
HPLC-Q
TOF-MS
MS
Dual Ligands Targeting Dopamine D-2 and Serotonin 5-HT1A Receptors as New Antipsychotical or Anti-Parkinsonian Agents
期刊论文
CURRENT MEDICINAL CHEMISTRY, 2014, 卷号: 21, 期号: 4, 页码: 437-457
作者:
Ye, Na
;
Song, Zilan
;
Zhang, Ao
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  |  
浏览/下载:31/0
  |  
提交时间:2019/01/08
Atypical antipsychotics
dopamine D-2 receptor
dual ligands
Parkinson's disease
Schizophrenia
Serotonin 5-HT1A receptor
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