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Discovery of Pyrrolo[2,3-d]pyrimidine derivatives as potent and selective colony stimulating factor 1 receptor kinase inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 243
作者:  Liang, Xiaofei;  Wang, Chun;  Wang, Beilei;  Liu, Juan;  Qi, Shuang
收藏  |  浏览/下载:29/0  |  提交时间:2022/12/23
Aberrations in peripheral inflammatory cytokine levels in substance use disorders: a meta-analysis of 74 studies 期刊论文
ADDICTION, 2020, 页码: 11
作者:  Wei, Ze-Xu;  Chen, Lei;  Zhang, Jian-Jun;  Cheng, Yong
收藏  |  浏览/下载:30/0  |  提交时间:2020/08/24
Evaluation of selected traditional Chinese medical extracts for bone mineral density maintenance: A mechanistic study. 期刊论文
Journal of traditional and complementary medicine, 2019, 卷号: 9, 期号: 3
作者:  Rebhun John F;  Du Qin;  Hood Molly;  Guo Hailing;  Glynn Kelly M
收藏  |  浏览/下载:45/0  |  提交时间:2019/12/05
Anti-inflammatory  BMD, bone mineral density  BSA, bovine serum albumin  Bmp4, bone morphogenic protein 4  CRE, cyclic adenosine monophosphate response element  CREB, cyclic adenosine monophosphate response element binding protein  DEXA, dual-energy X-ray absorptiometry  DMSO, Dimethyl sulfoxide  Drynaria fortunei  E2, estradiol  ER, estrogen receptor  ERE, estrogen response element  Epimedium brevicornu  Estrogenic  FBS, fetal bovine serum  Fsk, forskolin  Hprt, hypoxanthine-guanine phosphoribosyl-transferase  IL-1, interleukin 1  LBD, ligand binding domain  LBM, low bone mass  M-CSF, macrophage colony-stimulating factor  MAPK, mitogen activated protein kinase  NF-κβ, nuclear factor kappa beta  OP, osteoporosis  Osteoporosis  PTH, parathyroid hormone  PTHrp, PTH related peptide  RANKL, receptor activator of nuclear factor kappa beta ligand  RLU, relative luminescence unit  ROI, region of interest  Runx2, runt-related transcription factor 2  SFM, serum free media  TCM, traditional Chinese medicine  TNFα, tumor necrosis factor alpha  TRAP, tartrate-resistant acid phosphatase  UAS, upstream activating sequence  cAMP, cyclic adenosine monophosphate  qPCR, quantitative polymerase chain reaction  
Identification of compound D2923 as a novel anti-tumor agent targeting CSF1R 期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 11, 页码: 1768-1776
作者:  Liu, Ying-Qiang;  Wang, Ya-Nan;  Lu, Xiao-Yun;  Tong, Lin-Jiang;  Li, Yan
收藏  |  浏览/下载:110/0  |  提交时间:2019/01/08
Design, Synthesis, and Structure-Activity Relationship Study of 2-Oxo-3,4-dihydropyrimido[4,5-d]pyrimidines as New Colony Stimulating Factor 1 Receptor (CSF1R) Kinase Inhibitors 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 6, 页码: 2353-2371
作者:  Xun, Qiuju;  Zhang, Zhang;  Luo, Jinfeng;  Tong, Linjiang;  Huang, Minhao
收藏  |  浏览/下载:39/0  |  提交时间:2019/01/08
Fullerenol nanoparticles suppress RANKL-induced osteoclastogenesis by inhibiting differentiation and maturation 期刊论文
NANOSCALE, 2017, 卷号: 9, 期号: 34, 页码: 12516-12523
作者:  Geng H(耿会);  Chang YN(常亚男);  Bai X(白雪);  Yuan Q(袁卿);  Gu WH(古伟宏)
收藏  |  浏览/下载:38/0  |  提交时间:2019/08/27
Formaldehyde and co-exposure with benzene induce compensation of bone marrow and hematopoietic stem/progenitor cells in BALB/c mice during post-exposure period 期刊论文
Toxicology and Applied Pharmacology, 2017, 卷号: 324, 页码: 36-44
作者:  Wei, Chenxi;  Chen, Mouying;  You, Huihui;  Qiu, Feng;  Wen, Huaxiao
收藏  |  浏览/下载:11/0  |  提交时间:2019/12/23
8-OHdG  8-hydroxy-2′-deoxyguanosine  BZ  benzene  BM  bone marrow  BFU-E  burst-forming unit-erythroid  bw  body weight  CBC  complete blood count  CFU-GM  colony-forming unit-granulocyte-macrophage  CFU-HPP  high proliferative potential colony-forming unit  CSF  colony stimulating factor  DPC  DNA-protein crosslinks  EPO  erythropoietin  EPOR  EPO receptor  FA  formaldehyde  GRA  granulocytes  GM-CSF  granulocyte-macrophage colony stimulating factor  GM-CSFRα  GM-CSF receptor α  HGB  hemoglobin  HPCs  hematopoietic progenitor cells  HSCs  hematopoietic stem cells  IL-3  interleukin-3  IL-3Rα  IL-3 receptor α  LYM  lymphocytes  MCV  mean corpuscular volume  MON  monocytes  PLT  platelets  RBC  red blood cells  ROS  reactive oxygen species  WBC  white blood cells  Formaldehyde  Benzene  Hematotoxicity  Bone marrow  Myeloid progenitor  Post-exposure  
[Expressions of Spinal Macrophage Colony Stimulating Factor and Its Receptor CSF-1R in the Development ofComplicated Regional Pain Symptom I]. 期刊论文
Sichuan Da Xue Xue Bao Yi Xue Ban, 2016, 卷号: Vol.47 No.5, 页码: 703-707
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收藏  |  浏览/下载:6/0  |  提交时间:2019/03/05
Interleukin-4 and granulocyte-macrophage colony-stimulating factor mediates the upregulation of soluble vascular endothelial growth factor receptor-1 in RAW264.7 cells-a process in which p38 mitogen-activated protein kinase signaling has an important role 期刊论文
JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION, 2016, 卷号: 49, 期号: 3, 页码: 344-351
作者:  Xia, Lin;  Dong, Zhaogang;  Zhang, Yun;  Zhang, Xiaoying;  Song, Xiaobin
收藏  |  浏览/下载:8/0  |  提交时间:2019/12/16
A novel microRNA regulates osteoclast differentiation via targeting protein inhibitor of activated STAT3 (PIAS3) 期刊论文
Bone, 2014, 卷号: 67, 页码: 156-165
作者:  Liu, Ting;  Qin, Ai-Ping;  Liao, Bin;  Shao, Hui-Ge;  Guo, Li-Juan
收藏  |  浏览/下载:12/0  |  提交时间:2019/12/03
miRNAs  microRNAs  PIAS3  protein inhibitor of activated STAT3  M-CSF  macrophage colony stimulating factor  RANKL  receptor activator of nuclear factor-κB ligand  RANK  receptor activator of NF-κB  OPG  osteoprotegerin  MAPKs  mitogen-activated protein kinases  NFATc1  nuclear factor of activated T cells, calcineurin-dependent 1  PI3K  phosphatidylinositol 3-kinase  3′UTR  3′-untranslated region  MMP2  matrix metalloproteinase 2  MITF  microphthalmia-associated transcription factor  TRAP  tartrate-resistant acid phosphatase  CDS  coding sequences  RT-PCR  reverse transcription-PCR  WT  wild type  MT  mutant  qRT-PCR  quantitative real-time PCR  PIAS  protein inhibitor of activated STAT  STAT3  signal transducer and activator of transcription 3  OSCAR  osteoclast-associated receptor  MicroRNA  Osteoclast  Differentiation  PIAS3  Bone  


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