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期刊论文 [43]
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Advances in the development of imaging probes and aggregation inhibitors for alpha-synuclein
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 4, 页码: 483-498
作者:
Xu, Ming-ming
;
Ryan, Philip
;
Rudrawar, Santosh
;
Quinn, Ronald J.
;
Zhang, Hai-yan
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/07/01
Parkinson's disease
alpha-synuclein
imaging probes
aggregation inhibitors
thioflavin-T
mass spectrometry
advancesinthedevelopmentofimagingprobesandaggregationinhibitorsforalphasynuclein
期刊论文
actapharmacologicasinica, 2020, 卷号: 41, 期号: 4, 页码: 483
作者:
Xu Mingming
;
Ryan Philip
;
Rudrawar Santosh
;
Quinn Ronald J
;
Zhang Haiyan
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/07/01
Parkinson’s disease
alpha-synuclein
imaging probes
aggregation inhibitors
thioflavin-T
mass spectrometry
Disrupted network topology in dementia with Lewy bodies and comparision with Alzheimer's disease and Parkinson's disease dementia
会议论文
作者:
Lu, Jiaying
;
Wu, Ping
;
Guo, Qihao
;
Jiang, Jiehui
;
Zuo, Chuantao
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/05
Comparing the neuropsychological profiles of mild dementia with Lewy bodies and mild Alzheimer's disease
期刊论文
PSYCHOGERIATRICS, 2018, 卷号: 18, 期号: 1
作者:
Xu, Yan
;
Chen, Keliang
;
Zhao, Qianhua
;
Guo, Qihao
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
delayed recall
mild Alzheimer's disease
mild dementia with Lewy bodies
neuropsychology
Prion-like propagation of α-synuclein in the gut-brain axis
期刊论文
Brain Research Bulletin, 2018, 卷号: 140, 页码: 341-346
作者:
Chen, Ying
;
Shao, Qianhang
;
Yuan, Yu-He*
;
Chen, Nai-Hong*
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/27
CNS
central nervous system
DA
dopamine
DMV
dorsal motor nucleus of the vagus
ENS
enteric nervous system
GI
gastrointestinal
IL-1
interleukin-1
LBs
Lewy bodies
LPS
lipopolysaccharide
LAG3
lymphocyte-activation gene 3
MPTP
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
P301L
mutant Tau
PD
Parkinson's disease
PNS
peripheral nervous system
ROS
reactive oxygen species
SCFA
short chain fatty acids
SN
substantia nigra
TH
Tyrosine hydroxylase
TLR 2
Toll-like receptor 2
TNTs
tunneling nanotubes
α-synuclein
Prion-like
Enteric nervous system
Gut-brain axis
Non-motor symptom
Parkinson’s disease
Enzymatic O-GlcNAcylation of alpha-synuclein reduces aggregation and increases SDS-resistant soluble oligomers
期刊论文
NEUROSCIENCE LETTERS, 2017, 卷号: 655, 期号: -, 页码: 90-94
作者:
Zhang, JM
;
Lei, HZ
;
Chen, YB
;
Ma, YT
;
Jiang, F
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2018/08/30
Linked N-acetylglucosamine
Parkinsons-disease
Membrane Interactions
Mass-spectrometry
Toxicity
Brain
Phosphorylation
Ubiquitination
Proteins
Form
TrkB neurotrophic activities are blocked by alpha-synuclein, triggering dopaminergic cell death in Parkinson's disease
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2017, 卷号: 114, 期号: 40
作者:
Kang, Seong Su
;
Zhang, Zhentao
;
Liu, Xia
;
Manfredsson, Fredric P.
;
Benskey, Matthew J.
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
neurodegenerative diseases
dopamine
Lewy bodies
substantia nigra
Amyloidogenic proteins associated with neurodegenerative diseases activate the NLRP3 inflammasome
期刊论文
International Immunopharmacology, 2017, 卷号: 49, 页码: 155-160
作者:
Shao, Qian-hang
;
Zhang, Xiao-ling
;
Yang, Peng-fei
;
Yuan, Yu-he*
;
Chen, Nai-hong*
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/27
AD
Alzheimer's disease
ANSC
adult neural stem cell
Aβ
amyloid-β protein
CNS
central nervous system
DAMPs
danger-associated molecular patterns
IL-1
interleukin-1
LBs
Lewy bodies
NFTs
neurofibrillary tangles
NLRs
NOD-like receptors
PAMPs
pathogen-associated molecular patterns
PD
Parkinson's disease
PRRs
pattern recognition receptors
ROS
reactive oxygen species
SNpc
substantia nigra pars compacta
TLRs
toll-like receptors
α-Synuclein
Amyloid-β
Inflammation
NLRP3 inflammasome
Neurodegenerative disease
Impact of the alpha-Synuclein Initial Ensemble Structure on Fibrillation Pathways and Kinetics
期刊论文
JOURNAL OF PHYSICAL CHEMISTRY B, 2016, 卷号: 120, 期号: 12, 页码: 3140-3147
作者:
Bai, Jia
;
Cheng, Kai
;
Liu, Maili
;
Li, Conggang
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2016/07/12
alpha-synuclein-lanthanide metal ions interaction: binding sites, conformation and fibrillation
期刊论文
BMC BIOPHYSICS, 2016, 卷号: 9
作者:
Bai, Jia
;
Zhang, Zeting
;
Liu, Maili
;
Li, Conggang
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2016/04/18
alpha-synuclein (alpha S)
Lanthanide metal ions
Binding sites
Fibrillation
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