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Polymorphism rs2395655 affects LEDGF/p75 binding activity and p21WAF1/CIP1 gene expression in esophageal squamous cell carcinoma 期刊论文
2019, 卷号: 8, 期号: 5, 页码: 2313-2324
作者:  Guo, Rong;  Ma, Yunan;  Zhao, Min;  Zhang, Wenlong;  An, Guo
收藏  |  浏览/下载：3/0  |  提交时间：2020/01/03
Three-fragment fluorescence complementation for imaging of ternary complexes under physiological conditions 期刊论文
Analytical chemistry, 2018, 卷号: 90, 期号: 22, 页码: 13299-13305
作者:  Chen, Minghai;  Li, Wei;  Zhang, Zhi-Ping;  Pan, Jingdi;  Sun, Yuhan
收藏  |  浏览/下载：54/0  |  提交时间：2019/05/08
Discovery of novel 3-hydroxypicolinamides as selective inhibitors of HIV-1 integrase-LEDGF/p75 interaction 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 125, 页码: 1051-1063
作者:  Zhang, Feng-Hua;  Debnath, Bikash;  Xu, Zhong-Liang;  Yang, Liu-Meng;  Song, Li-Rui
收藏  |  浏览/下载：12/0  |  提交时间：2019/01/08
Study of Structure-active Relationship for Inhibitors of HIV-1 Integrase LEDGF/p75 Interaction by Machine Learning Methods 期刊论文
2017, 卷号: 36, 期号: 7
作者:  Li, Yang;  Wu, Yanbin;  Yan, Aixia
收藏  |  浏览/下载：10/0  |  提交时间：2020/01/04
Discovery of novel 3-hydroxypicolinamides as selective inhibitors of HIV-1 integrase-LEDGF/p75 interaction 期刊论文
European Journal of Medicinal Chemistry, 2017, 卷号: 125, 期号: X, 页码: 1051-1063
作者:  Zhang FH;  Debnath B;  Zheng YT;  Neamati N[*];  Long YQ[*]
收藏  |  浏览/下载：72/0  |  提交时间：2016/11/07
A Novel Assay for Screening Inhibitors Targeting HIV Integrase LEDGF/p75 Interaction Based on Ni2+ Coated Magnetic Agarose Beads 期刊论文
2016, 卷号: 6, 页码: 33477
作者:  Zhang Dawei;  He Hongqiu;  Liu Mengmeng;  Meng Zhixia;  Guo Shunxing
收藏  |  浏览/下载：3/0  |  提交时间：2020/01/04
基于界面结构的多靶点HIV-1整合酶抑制剂的发现和结构优化 会议论文
作者:  张凤华;  许忠良;  李博文;  龙亚秋
收藏  |  浏览/下载：17/0  |  提交时间：2019/01/08
Dermatomyositis, polymyositis and immune-mediated necrotising myopathies 期刊论文
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2015, 卷号: 1852, 期号: 4, 页码: 622-632
作者:  Luo, Yue-Bei;  Mastaglia, Frank L
收藏  |  浏览/下载：11/0  |  提交时间：2019/12/03
BAFF  B cell-activating factor  BLTK  B lymphoid tyrosine kinase  CCL21  chemokine (C-C motif) ligand 2  CK  creatine kinase  DC  dendritic cell  CTD  connective tissue disease  DFS70  dense fine speckled 70  DM  dermatomyositis  HIV  human immunodeficiency virus  HLA  human leukocyte antigen  HMGCR  3-hydroxy-3-methyl-glutaryl-CoA reductase  HTLV-1  human T cell leukaemia virus  IBM  inclusion body myositis  IFIH1  interferon induced with helicase C domain protein 1  IL  interleukin  IMNM  immune-mediated necrotising myopathies  INF  interferon  IP-10  INFγ-inducible 10-kD protein  ISG15  IFN-stimulated gene 15  I-TAC  IFN-inducible T cell α chemoattractant  LEDGF  lens epithelium-derived growth factor  MAC  membrane attack complex  MCP-1  monocyte chemoattractant protein-1  MCTD  mixed connective tissue disease  MDA5  melanoma differentiation-associated gene 5  MHC  major histocompatibility complex  MIF  macrophage inhibition factor  MIP-1α  macrophage inflammatory protein 1α  miRNA  microRNA  MxA  myxovirus resistance 1 protein  NuRD  nucleosome remodelling deacetylase complex  NXP-2  nuclear matrix protein 2  pDC  plasmacytoid dendritic cell  PKCε  protein kinase C ε type  PLCL1  phospholipase C like-1  PM  polymyositis  PTPN  protein tyrosine phosphatase N22 gene  SRP  signal recognition particle  RNP  ribonuclear protein complex  TIF  transcription intermediary factor  TLR  Toll like receptor  TNF  tumour necrosis factor  VCAM1  vascular cell adhesion molecule 1  VEGF  vascular endothelial growth factor  Idiopathic inflammatory myopathy  Polymyositis  Dermatomyositis  Immune-mediated necrotising myopathy  Autoantibody  
2-Aryl-3-carbonylquinolones: Design, Synthesis and Biological Evaluation of Novel HCV NS5B Polymerase Inhibitors 期刊论文
ACTA CHIMICA SINICA, 2014, 卷号: 72, 期号: 8, 页码: 906-913
作者:  Wang Shenfeng;  Lin Jianping;  He Peilan;  Zuo Jianping;  Long Yaqiu
收藏  |  浏览/下载：13/0  |  提交时间：2019/01/08
Design and discovery of flavonoid-based HIV-1 integrase inhibitors targeting both the active site and the interaction with LEDGF/p75 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2014, 卷号: 22, 期号: 12, 页码: 3146-3158
作者:  Li, Bo-Wen;  Zhang, Feng-Hua;  Serrao, Erik;  Chen, Huan;  Sanchez, Tino W.
收藏  |  浏览/下载：16/0  |  提交时间：2019/01/08

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