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上海有机化学研究所 [13]
湖南农业大学 [8]
昆明植物研究所 [5]
湖南大学 [2]
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期刊论文 [31]
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Induction of oxidative stress, apoptosis and DNA damage by koumine in Tetrahymena thermophila
期刊论文
PLOS ONE, 2019, 卷号: 14, 期号: 2
作者:
Ye, Qiao
;
Zhang, Chaonan
;
Wang, Zhenlu
;
Feng, Yongyong
;
Zhou, Aiguo
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/12/05
Protective Effect of Koumine, an Alkaloid from Gelsemium Sempervirens, on Injury Induced by H₂O₂ in IPEC-J2 Cells.
期刊论文
International journal of molecular sciences, 2019, 卷号: Vol.20 No.3
作者:
Zhihang Yuan
;
Zengenni Liang
;
Jine Yi
;
Xiaojun Chen
;
Rongfang Li
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/17
H2O2
IPEC-J2
cells
apoptosis
koumine
Gelsemine and koumine, principal active ingredients of Gelsemium, exhibit mechanical antiallodynia via spinal glycine receptor activation-induced allopregnanolone biosynthesis
期刊论文
Biochemical Pharmacology, 2019
作者:
Rana Muhammad Shoaib
;
Jing-Yang Zhang
;
Xiao-Fang Mao
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/13
Gelsemine
Koumine
Glycine
receptor
3α-HSOR
Allopregnanolone
A novel two-dimensional liquid chromatography system for the simultaneous determination of three monoterpene indole alkaloids in biological matrices
期刊论文
Analytical and Bioanalytical Chemistry, 2019, 卷号: 411, 期号: 17, 页码: 3857-3870
作者:
Liu, Sha-Sha
;
Yang, Kun
;
Sun, Zhi-Liang
;
Zheng, Xiaofeng
;
Bai, Xia
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/23
Gelsemine
Gelsemium
Humantenmine
Indole alkaloid
Koumine
Two-dimensional liquid chromatography
The Difference in Cytotoxic Activity between Two Optical Isomers of Gelsemine from Gelsemium elegans Benth. on PC12 Cells
期刊论文
Molecules, 2019, 卷号: 24, 期号: 10, 页码: 2004-
作者:
Lin, Li
;
Liu, Yan-Chun
;
Liu, Zhao-Ying*
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  |  
浏览/下载:8/0
  |  
提交时间:2019/12/23
Gelsemium elegans
PC12 cells
gelsemine
koumine
Protective Effect of Koumine, an Alkaloid from Gelsemium Sempervirens, on Injury Induced by H(2)O(2) in IPEC-J2 Cells.
期刊论文
International journal of molecular sciences, 2019, 卷号: 20, 期号: 3
作者:
Yuan, Zhihang
;
Liang, Zengenni
;
Yi, Jine
;
Chen, Xiaojun
;
Li, Rongfang
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/23
H2O2
IPEC-J2 cells
apoptosis
koumine
Development and in-house validation of a sensitive LC–MS/MS method for simultaneous quantification of gelsemine, koumine and humantenmine in porcine plasma
期刊论文
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 2018, 卷号: 1076, 页码: 54-60
作者:
Yang, Kun
;
Long, Xue-Ming
;
Liu, Yan-Chun
;
Chen, Fu-Hua
;
Liu, Xiao-Feng
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  |  
浏览/下载:5/0
  |  
提交时间:2019/12/23
Indole alkaloid
Gelsemine
Gelsemium elegans
Plasma
Koumine
Humantenmine
Fingerprint analysis of Gelsemium elegans by HPLC followed by the targeted identification of chemical constituents using HPLC coupled with quadrupole-time-of-flight mass spectrometry
期刊论文
Fitoterapia, 2017, 卷号: 121, 页码: 94-105
作者:
Liu, Yan-Chun
;
Lin, Li
;
Cheng, Pi
;
Sun, Zhi-Liang
;
Wu, Yong
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/23
HPLC
high-performance liquid chromatography
HPLC-QqTOF MS
high-performance liquid chromatography quadrupole time-of-flight mass spectrometry
LC
liquid chromatography
LOD
The limit of detection
LOQ
limit of quantification
MS/MS
tandem mass spectrometry
QqTOF MS
quadrupole time-of-flight mass spectrometry
RT
retention time
S/N
signal-to-noise
TOF
time-of-flight
TIC
total ion chromatogram
Dehydrokoumidine (PubChem CID:119077162)
Ferulic acid (PubChem CID:445858)
7-Deoxygelsemide or 9-Deoxygelsemide (PubChem CID:101413879 or 46176622)
Gelsemine (PubChem CID:5390854)
14-Acetoxy-15-hydroxygelsenicine (PubChem CID:102185548)
GSIR-1 (PubChem CID:11105986)
Gelsemiol (PubChem CID:10375526)
14-hydroxygelsemicine (PubChem CID:22217388)
14-Hydroxygelsenicine (PubChem CID:14217347)
Koumine (PubChem CID:91895267)
GS-2 (PubChem CID:12070888)
Koumidine (PubChem CID:44584550)
Gelsenicine (PubChem CID: 21123652)
Gelsemicine (PubChem CID: 54624 28)
Gelseoxazolidinine (PubChem CID:102297300)
Gelsevirine (PubChem CID:14217344)
19R–Hydroxydihydrogelsemine (PubChem CID:101601182)
Humantenine (PubChem CID:44593672)
11-hydroxyhumantenine (PubChem CID:5318224)
14-Acetoxygelsenicine (PubChem CID:102185547)
Sempervirine (PubChem CID:168919)
Pyrogallol (PubChem CID:105)
Gallic acid (PubChem CID:370)
Gelsemiol-3-glucoside (PubChem CID:101098709)
Semperoside (PubChem CID:11439812)
Gelsemium elegans
Mass spectrometry
Alkaloids, fingerprint
HPLC
Chemical constituents
Structural elucidation of koumine metabolites by accurate mass measurements using high-performance liquid chromatography/quadrupole-time-of-flight mass spectrometry
期刊论文
Rapid Communications in Mass Spectrometry, 2017, 卷号: 31, 期号: 3, 页码: 309-314
作者:
Xiao, Sa
;
Huang, Ya-Jun
;
Sun, Zhi-Liang
;
Liu, Zhao-Ying*
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/23
Five new koumine-type alkaloids from the roots of Gelsemium elegans
期刊论文
2017, 卷号: 118, 页码: 112
作者:
Zhang, Wei[1,2]
;
Zhang, Sheng-Yuan[2,4]
;
Wang, Gui-Yang[2]
;
Li, Ni-Ping[2]
;
Chen, Min-Feng[2]
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/06
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