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上海药物研究所 [53]
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Discovery of a novel jellyfish venom metalloproteinase inhibitor from secondary metabolites isolated from jellyfish-derived fungus Aspergillus versicolor SmT07
期刊论文
CHEMICO-BIOLOGICAL INTERACTIONS, 2022, 卷号: 365, 页码: 8
作者:
Yue, Yang
;
Yu, Huahua
;
Suo, Qishan
;
Li, Rongfeng
;
Liu, Song
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2023/01/04
Nemopilema nomurai
Jellyfish envenomations
Aspergillus versicolor
Metalloproteinase inhibitors
Molecular docking
Jellyfish Nemopilema nomurai causes myotoxicity through the metalloprotease component of venom
期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2022, 卷号: 151, 页码: 8
作者:
Li, Aoyu
;
Yu, Huahua
;
Li, Rongfeng
;
Yue, Yang
;
Yu, Chunlin
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/07/18
Jellyfish envenomation
Nemopilema nomurai nematocyst venom
(NnNV)
Myotoxicity
Metalloprotease
Design, synthesis, in vitro evaluation of a new pyrrolo[1,2-a]thiazolo[5,4-d]pyrimidinone derivatives as cholinesterase inhibitors against Alzheimer's disease
期刊论文
JOURNAL OF HETEROCYCLIC CHEMISTRY, 2022, 卷号: 59, 期号: 6, 页码: 1086-1101
作者:
Zeng, Y (Zeng, Yan) [1] , [2]
;
Nie, LF (Nie, Lifei) [1]
;
Liu, L (Liu, Liu) [1]
;
Niu, C (Niu, Chao) [1] , [2]
;
Li, Y (Li, Yi) [1] , [2]
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2022/06/21
Identification of pyrogallol as a warhead in design of covalent inhibitors for the SARS-CoV-2 3CL protease
期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 12
作者:
Su, Haixia
;
Yao, Sheng
;
Zhao, Wenfeng
;
Zhang, Yumin
;
Liu, Jia
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  |  
浏览/下载:30/0
  |  
提交时间:2021/08/17
Inhibition effects of poly(N-vinylcaprolactam)/poly(epsilon-caprolactone) amphiphilic block copolymers on methane hydrate formation
期刊论文
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY, 2021, 卷号: 96, 页码: 183-193
作者:
Wan, Li
;
De Qing Liang
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  |  
浏览/下载:22/0
  |  
提交时间:2021/10/27
Hydrate inhibitors
Amphiphilic block copolymer
PVCap
Micellization
Biodegradability
Discovery of 5-Benzylidene-2-phenyl-1,3-dioxane-4,6-diones as Highly Potent and Selective SIRT1 Inhibitors
期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 12, 期号: 3, 页码: 397-403
作者:
Li, Chunpu
;
Hu, Sha-Sha
;
Yang, Lisheng
;
Wang, Min
;
Long, Jian-Dong
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2021/05/24
SIRT1
inhibitor
structure-activity relationship
interaction
deacetylase
Discovery of New alpha-Glucosidase Inhibitors: Structure-Based Virtual Screening and Biological Evaluation
期刊论文
FRONTIERS IN CHEMISTRY, 2021, 卷号: 9, 页码: 9
作者:
Liu, Shan-Kui
;
Hao, Haifang
;
Bian, Yuan
;
Ge, Yong-Xi
;
Lu, Shengyuan
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  |  
浏览/下载:59/0
  |  
提交时间:2021/05/24
α
-glycosidase
virtual screening
cytotoxicity
type 2 diabetes
molecular docking
In situ PXRD analysis on the kinetic effect of PVP-K90 and PVCap on methane hydrate dissociation below ice point
期刊论文
FUEL, 2021, 卷号: 286, 页码: 9
作者:
Zhou, Xuebing
;
Zhang, Qian
;
Long, Zhen
;
Liang, Deqing
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2021/10/25
Methane hydrate
Hydrate dissociation
X-ray diffraction
Self-preservation effect
Natural Potent NAAA Inhibitor Atractylodin Counteracts LPS-Induced Microglial Activation
期刊论文
FRONTIERS IN PHARMACOLOGY, 2020, 卷号: 11, 页码: 9
作者:
Yang, Longhe
;
Ji, Chunyan
;
Li, Yitian
;
Hu, Fan
;
Zhang, Fang
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/12/10
NAAA inhibitor
atractylodin
>
anti-inflammation
microglia
traditional Chinese medicine
Design, Synthesis, and Biological Evaluation of 8-Mercapto-3,7-Dihydro-1H-Purine-2,6-Diones as Potent Inhibitors of SIRT1, SIRT2, SIRT3, and SIRT5
期刊论文
MOLECULES, 2020, 卷号: 25, 期号: 12, 页码: 18
作者:
Han, Haozhen
;
Li, Chunpu
;
Li, Man
;
Yang, Lisheng
;
Zhao, Sen
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2020/12/24
sirtuins
inhibitor
structure-activity relationship
deacetylase
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