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四川大学 [17]
上海药物研究所 [16]
厦门大学 [7]
植物研究所 [7]
北京大学 [6]
清华大学 [4]
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期刊论文 [84]
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Salinity Acclimation Induces Reduced Energy Metabolism, Osmotic Pressure Regulation and Transcriptional Reprogramming in Hypotrichida Ciliate
Gastrostyla setifera
期刊论文
JOURNAL OF OCEAN UNIVERSITY OF CHINA, 2024, 卷号: 23, 期号: 2, 页码: 539-549
作者:
Ji, Xin
;
Bi, Luping
;
Zou, Songbao
;
Li, Wenlu
;
Ji, Daode
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/23
salinity stress
heterotrophic protist
ciliate
Gastrostyla setifera
transcriptome
differentially expressed gene
Comparative proteomic and phosphoproteomic analysis reveals differential heat response mechanism in two congeneric oyster species
期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2023, 卷号: 263, 页码: 19
作者:
Wang, Chaogang
;
Du, Mingyang
;
Jiang, Zhuxiang
;
Cong, Rihao
;
Wang, Wei
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/12/13
Heat stress
Oysters
Crassostrea angulata
Crassostrea gigas
Phosphorylation
Cryo-EM structures of PI3K alpha reveal conformational changes during inhibition and activation
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 45, 页码: 9
作者:
Liu, Xiao
;
Yang, Su
;
Hart, Jonathan R.
;
Xu, Yingna
;
Zou, Xinyu
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2022/01/04
phosphoinositide 3-kinase (PI3K)
activation
inhibition
activity-dependent conformational changes
Nuclear UHRF1 is a gate-keeper of cellular AMPK activity and function
期刊论文
CELL RESEARCH, 2021, 页码: 18
作者:
Xu, Xiang
;
Ding, Guangjin
;
Liu, Caizhi
;
Ding, Yuhan
;
Chen, Xiaoxin
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  |  
浏览/下载:63/0
  |  
提交时间:2021/11/04
Synthesis, biological evaluation and structure-activity relationship of novel dichloroacetophenones targeting pyruvate dehydrogenase kinases with potent anticancer activity
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 214, 页码: 16
作者:
Xu, Biao
;
Wang, Zhi-Peng
;
Liu, Qingwang
;
Yang, Xiaohong
;
Li, Xuemin
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  |  
浏览/下载:24/0
  |  
提交时间:2021/05/17
Pyruvate dehydrogenase kinase
Proliferation
Cancer metabolism
Structure-activity relationship
Synthesis, biological evaluation and structure-activity relationship of novel dichloroacetophenones targeting pyruvate dehydrogenase kinases with potent anticancer activity
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 214
作者:
Xu, Biao
;
Wang, Zhi-Peng
;
Liu, Qingwang
;
Yang, Xiaohong
;
Li, Xuemin
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2021/04/26
Pyruvate dehydrogenase kinase
Proliferation
Cancer metabolism
Structure-activity relationship
Energy-efficient butanol production by Clostridium acetobutylicum with histidine kinase knockouts to improve strain tolerance and process robustness
期刊论文
GREEN CHEMISTRY, 2021, 卷号: 23, 期号: 5, 页码: 2155-2168
作者:
Du, Guangqing
;
Zhu, Chao
;
Xu, Mengmeng
;
Wang, Lan
;
Yang, Shang-Tian
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/08/31
Repurposing of Kinase Inhibitors for Treatment of COVID-19
期刊论文
PHARMACEUTICAL RESEARCH, 2020, 卷号: 37
作者:
Weisberg, Ellen
;
Parent, Alexander
;
Yang, Priscilla L.
;
Sattler, Martin
;
Liu, Qingsong
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2020/10/26
Coronavirus
SARS-CoV-2
SARS-CoV
MERS-CoV
kinase inhibitors
pharmacokinetics
antiviral therapy
COVID-19
Inhibition of JNK ameliorates depressive-like behaviors and reduces the activation of pro-inflammatory cytokines and the phosphorylation of glucocorticoid receptors at serine 246 induced by neuroinflammation
期刊论文
PSYCHONEUROENDOCRINOLOGY, 2020, 卷号: 113, 页码: 10
作者:
Zhang, Juntao
;
Lin, Wenjuan
;
Tang, Mingming
;
Zhao, Yawei
;
Zhang, Ke
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/05/18
Neuroinflammation
Depressive-like behavior
JNK
Proinflammatory cytokines
Glucocorticoid receptor
A nucleoside diphosphate kinase gene OsNDPK4 is involved in root development and defense responses in rice (Oryza sativa L.)
期刊论文
PLANTA, 2020, 卷号: 251, 期号: 4
作者:
Ye, Jin
;
Ding, Wona
;
Chen, Yujie
;
Zhu, Xinni
;
Sun, Jiutong
收藏
  |  
浏览/下载:69/0
  |  
提交时间:2020/12/16
OXIDATIVE STRESS
PROTEOMIC ANALYSIS
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