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科研机构
上海药物研究所 [19]
上海中医药大学 [6]
大连化学物理研究所 [2]
武汉大学 [1]
兰州化学物理研究所 [1]
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期刊论文 [28]
会议论文 [1]
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2023 [1]
2020 [1]
2019 [1]
2018 [3]
2017 [2]
2016 [3]
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浏览/检索结果:
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Effect of Adulteration on Quality and Preliminary Risk Assessment of the Decoction Pieces of Farfarae Flos Based on the Determination of Hepatotoxic Pyrrolizidine Alkaloids by UHPLC-MS/MS
期刊论文
Journal of AOAC International, 2023, 卷号: 106, 期号: 1, 页码: 192-204
作者:
An-Ping Li
;
Shi YP(师彦平)
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浏览/下载:0/0
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提交时间:2023/10/31
Tu-San-Qi (Gynura japonica): the culprit behind pyrrolizidine alkaloid-induced liver injury in China
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:
Zhu, Lin
;
Zhang, Chun-yuan
;
Li, Dong-ping
;
Chen, Hu-biao
;
Ma, Jiang
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浏览/下载:18/0
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提交时间:2020/12/24
herb-induced liver injury
hepatic sinusoidal obstruction syndrome
pyrrolizidine alkaloids
Tu-San-Qi
Gynura japonica
Intestinal and hepatic biotransformation of pyrrolizidine alkaloid N-oxides to toxic pyrrolizidine alkaloids
期刊论文
ARCHIVES OF TOXICOLOGY, 2019, 卷号: 93, 期号: 8, 页码: 2197-2209
作者:
Yang, Mengbi
;
Ma, Jiang
;
Ruan, Jianqing
;
Ye, Yang
;
Fu, Peter Pi-Cheng
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  |  
浏览/下载:9/0
  |  
提交时间:2020/07/01
Pyrrolizidine alkaloid N-oxides
Pyrrolizidine alkaloids
Pyrrolizidine alkaloid N-oxide toxicity
Biotransformation of pyrrolizidine alkaloid N-oxides
Microbiota biotransformation
The role of formation of pyrrole-ATP synthase subunit beta adduct in pyrrolizidine alkaloid-induced hepatotoxicity
期刊论文
ARCHIVES OF TOXICOLOGY, 2018, 卷号: 92, 期号: 11, 页码: 3403-3414
作者:
Lu, Yao
;
Ma, Jiang
;
Song, Zijing
;
Ye, Yang
;
Fu, Peter P.
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浏览/下载:38/0
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提交时间:2019/01/08
Pyrrolizidine alkaloid
Retrorsine
ATP5B
Mitochondrial damage
Pyrrole-protein adduct
Gynura Rhizoma containing pyrrolizidine alkaloids induces the hepatic sinusoidal obstruction syndrome in mice via upregulating fibrosis-related factors
期刊论文
Acta pharmacologica Sinica, 2018
作者:
Zhang, Fang
;
Zhou, Yue
;
Yang, Xiao
;
Xiong, Ai-Zhen
;
Wang, Zheng-Tao
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浏览/下载:16/0
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提交时间:2019/01/08
Contamination of hepatotoxic pyrrolizidine alkaloids in retail honey in China
期刊论文
FOOD CONTROL, 2018, 卷号: 85, 页码: 484-494
作者:
Zhu, Lin
;
Wang, Zhangting
;
Wong, Lailai
;
He, Yisheng
;
Zhao, Zhongzhen
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浏览/下载:28/0
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提交时间:2019/01/08
Food safety
China honey
Pyrrolizidine alkaloid
Pollen analysis
LC-MS analysis
First evidence of pyrrolizidine alkaloid N-oxide-induced hepatic sinusoidal obstruction syndrome in humans
期刊论文
ARCHIVES OF TOXICOLOGY, 2017, 卷号: 91, 期号: 12, 页码: 3913-3925
作者:
Yang, Mengbi
;
Ruan, Jianqing
;
Gao, Hong
;
Li, Na
;
Ma, Jiang
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浏览/下载:27/0
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提交时间:2019/01/08
Pyrrolizidine alkaloid N-oxide
Pyrrolizidine alkaloid
Hepatic sinusoidal obstruction syndrome
Pyrrole-protein adduct
Biotransformation
Toxicokinetic
Integrative analysis of hepatic microRNA and mRNA to identify potential biological pathways associated with monocrotaline-induced liver injury in mice
期刊论文
Toxicology and applied pharmacology, 2017, 卷号: 333, 页码: 35-42
作者:
Huang, Zhenlin
;
Chen, Minwei
;
Zhang, Jiaqi
;
Sheng, Yuchen
;
Ji, Lili
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浏览/下载:28/0
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提交时间:2019/01/08
A novel ultra-performance liquid chromatography hyphenated with quadrupole time of flight mass spectrometry method for rapid estimation of total toxic retronecine-type of pyrrolizidine alkaloids in herbs without requiring corresponding standards
期刊论文
FOOD CHEMISTRY, 2016, 卷号: 194, 页码: 1320-1328
作者:
Zhu, Lin
;
Ruan, Jian-Qing
;
Li, Na
;
Fu, Peter P.
;
Ye, Yang
收藏
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浏览/下载:13/0
  |  
提交时间:2019/01/08
Food safety
Hepatotoxic
Pyrrolizidine alkaloids
Retronecine type
UHPLC-MS
9-Glutathiony1-6,7-dihydro-1-hydroxymethy1-5H-pyrrolizine Is the Major Pyrrolic Glutathione Conjugate of Retronecine-Type Pyrrolizidine Alkaloids in Liver Microsomes and in Rats
期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2016, 卷号: 29, 期号: 2, 页码: 180-189
作者:
Chen, Meixia
;
Li, Liang
;
Zhong, Dafang
;
Shen, Shuijie
;
Zheng, Jiang
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  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
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