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科研机构
北京大学 [4]
中南大学 [1]
昆明动物研究所 [1]
内容类型
期刊论文 [6]
发表日期
2013 [2]
2006 [1]
2003 [2]
2002 [1]
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Synthesis and biological characterization of synthetic analogs of Huwentoxin-IV (Mu-theraphotoxin-Hh2a), a neuronal tetrodotoxin-sensitive sodium channel inhibitor
期刊论文
Toxicon, 2013, 卷号: 71, 页码: 57-65
作者:
Deng, Meichun*
;
Luo, Xuan
;
Jiang, Liping
;
Chen, Hanchun
;
Wang, Jun
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/03
DRG
Dorsal root ganglion
HPLC
HWTX
HWTX-IV
High pressure liquid chromatography
Huwentoxin
IC(50)
ICK
Inhibitor cystine knot
Kv channel
MALDI-TOF
Matrix assisted laser desorption/ionization time-of-flight
Median inhibitory concentration
Mutant
Patch-clamp
Protein folding
Solid-phase peptide synthesis
TTX
TTX-R
TTX-S
TTX-resistant
TTX-sensitive
Tetrodotoxin
VGSC
Voltage-gated potassium channel
Voltage-gated sodium channel
Native Pyroglutamation of Huwentoxin-IV: A Post-Translational Modification that Increases the Trapping Ability to the Sodium Channel
期刊论文
PLOS ONE, 2013, 卷号: 6, 期号: 8, 页码: e65984
作者:
Rong MQ
;
Duan ZG
;
Chen JL
;
Li JL
;
Xiao YC
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2013/12/13
Function and solution structure of huwentoxin-X, a specific blocker of N-type calcium channels, from the Chinese bird spider Ornithoctonus huwena
期刊论文
journal of biological chemistry, 2006
Li, ZH
;
Dai, J
;
Dai, LJ
;
Deng, MC
;
Zhu, Z
;
Hu, WJ
;
Liang, SP
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2015/11/14
OMEGA-CONOTOXIN GVIA
SELENOCOSMIA-HUWENA
CA2+ CHANNELS
HAINANTOXIN-IV
PEPTIDE TOXINS
VENOM
AFFINITY
RELEASE
ANTINOCICEPTION
IDENTIFICATION
cDNA sequence analysis of seven peptide toxins from the spider Selenocosmia huwena
期刊论文
toxicon official journal of the international society on toxinology, 2003
Diao Jianbo
;
Lin Ying
;
Tang Jianzhou
;
Liang Songping
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2015/11/11
cDNA sequence analysis of seven peptide toxins from the spider Selenocosmia huwena
期刊论文
toxicon, 2003
Diao, JB
;
Lin, Y
;
Tang, JZ
;
Liang, SP
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2015/11/12
cDNA sequence
RACE
huwentoxin
inhibitor cystine knot motif
superfamily
Selenocosmia huwena
HUWENTOXIN-I
PHONEUTRIA-NIGRIVENTER
MOLECULAR-CLONING
CYSTINE KNOT
VENOM
CHANNELS
CONOTOXINS
POTENT
MOTIF
The structure of spider toxin huwentoxin-II with unique disulfide linkage: Evidence for structural evolution
期刊论文
蛋白质科学, 2002
Shu, Q
;
Lu, SY
;
Gu, XC
;
Liang, SP
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2015/11/11
humentoxin-II
spider toxin
three-dimensional structure
disulfide bond
inhibitor cystine knot motif
disulfide-directed beta-hairpin
two-dimensional NMR
FUNNEL-WEB SPIDER
CALCIUM-CHANNEL ANTAGONIST
OMEGA-AGA-IVB
3-DIMENSIONAL STRUCTURE
SELENOCOSMIA-HUWENA
SODIUM-CHANNEL
CYSTINE KNOT
VENOM
NEUROTOXINS
POLYPEPTIDES
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