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Hypoglycemic effect of Nitraria tangutorum fruit by inhibiting glycosidase and regulating IRS1/PI3K/AKT signalling pathway and its active ingredient identification by UPLC-MS
期刊论文
FOOD & FUNCTION, 2023, 卷号: 14, 期号: 17, 页码: 7869
作者:
Jiang, Sirong
;
Wang, Luya
;
Jia, Wenjing
;
Wu, Di
;
Wu, Li
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/12/01
GSK3 beta palmitoylation mediated by ZDHHC4 promotes tumorigenicity of glioblastoma stem cells in temozolomide-resistant glioblastoma through the EZH2-STAT3 axis
期刊论文
ONCOGENESIS, 2022, 卷号: 11
作者:
Zhao, Chenggang
;
Yu, Huihan
;
Fan, Xiaoqing
;
Niu, Wanxiang
;
Fan, Junqi
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  |  
浏览/下载:13/0
  |  
提交时间:2022/12/23
Glycogen synthase kinase 3 beta inhibition synergizes with PARP inhibitors through the induction of homologous recombination deficiency in colorectal cancer
期刊论文
CELL DEATH & DISEASE, 2021, 卷号: 12, 期号: 2, 页码: 18
作者:
Zhang, Ning
;
Tian, Yu-Nan
;
Zhou, Li-Na
;
Li, Meng-Zhu
;
Chen, Hua-Dong
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  |  
浏览/下载:21/0
  |  
提交时间:2021/05/24
Development of Bisindole-Substituted Aminopyrazoles as Novel GSK-3 beta Inhibitors with Suppressive Effects against Microglial Inflammation and Oxidative Neurotoxicity
期刊论文
ACS CHEMICAL NEUROSCIENCE, 2020, 卷号: 11, 期号: 20, 页码: 3398-3408
作者:
Liu, Jian-Guo
;
Zhao, Danfeng
;
Gong, Qi
;
Bao, Fengxia
;
Chen, Wen-Wen
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  |  
浏览/下载:16/0
  |  
提交时间:2021/05/24
Glycogen synthase kinase-3
bisindole-substituted aminopyrazoles
Alzheimer's disease
oxidative neurotoxicity
microglial inflammation
Gandou decoction, a Chinese medicinal formula, in the treatment of hepatic injury by Wnt/beta-catenin pathway regulation in models of Wilson disease
期刊论文
ANNALS OF PALLIATIVE MEDICINE, 2020, 卷号: 9
作者:
Gao, Manli
;
Geng, Hao
;
Wu, Peng
;
Dong, Jianjian
;
Li, Hai
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  |  
浏览/下载:122/0
  |  
提交时间:2020/11/30
Wilson disease (WD)
liver injury
Gandou decoction (GDD)
Wnt/beta-catenin pathway
oxidative stress
Repurposing antimycotic ciclopirox olamine as a promising anti-ischemic stroke agent
期刊论文
ACTA PHARMACEUTICA SINICA B, 2020, 卷号: 10, 期号: 3, 页码: 434-446
作者:
Feng, Hongxuan
;
Hu, Linghao
;
Zhu, Hongwen
;
Tao, Lingxue
;
Wu, Lei
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/07/01
Blood-brain barrier
Brain ischemia
Cell cycle
Inflammation
Neuroprotection
Typical halogenated flame retardants affect human neural stem cell gene expression during proliferation and differentiation via glycogen synthase kinase 3 beta and T3 signaling
期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2019, 卷号: 183, 页码: -
作者:
Liang, Shaojun
;
Liang, Shengxian
;
Zhou, Hui
;
Yin, Nuoya
;
Faiola, Francesco
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  |  
浏览/下载:22/0
  |  
提交时间:2020/09/10
Human neural stem cells (hNSCs)
TBBPA/TBBPS/TCBPA
BDE-209/BDE-47
Human neural developmental toxicity
GSK3 beta
T3 signaling
Nitazoxanide, an anti-parasitic drug, efficiently ameliorates learning and memory impairments in AD model mice
期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 10, 页码: 1279-1291
作者:
Fan, Lei
;
Qiu, Xiao-xia
;
Zhu, Zhi-yuan
;
Lv, Jian-lu
;
Lu, Jian
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/07/01
Alzheimer's disease
nitazoxanide
autophagy
inflammation
APP/PS1 transgenic mice
SCFFBXW7/GSK3 beta-Mediated GFI1 Degradation Suppresses Proliferation of Gastric Cancer Cells
期刊论文
CANCER RESEARCH, 2019, 卷号: 79, 期号: 17, 页码: 4387-4398
作者:
Kuai, Xiaoling
;
Li, Long
;
Chen, Ran
;
Wang, Kangjunjie
;
Chen, Min
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2020/07/01
Bryostatin-1 inhibits cell proliferation of hepatocarcinoma and induces cell cycle arrest by activation of GSK3 beta
期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2019, 卷号: 512, 期号: 3
作者:
Wang, Jianfeng
;
Wang, Zhicheng
;
Sun, Yu
;
Liu, Dahai
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2019/12/05
Bryostatin-1
Cell cycle arrest
Ubiquitination degradation
Marine drug
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