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Small Molecule SHP2 Inhibitor LXQ-217 affects Lung Cancer Cell Proliferation in Vitro and in Vivo
期刊论文
CHEMISTRY & BIODIVERSITY, 2024, 页码: 11
作者:
Sun, Hao
;
Bai, Xiaoyi
;
Zhang, Yiting
;
Gao, Yanan
;
Dai, Jiajia
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/06/04
Anti-tumor
SHP2
Orthosteric inhibitor
Apoptosis
Bromophenol
Acetaldehyde induces similar cytotoxic and genotoxic risks in BEAS-2B cells and HHSteCs: involvement of differential regulation of MAPK/ERK and PI3K/AKT pathways
期刊论文
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 2023, 卷号: 30
作者:
Zhang, Jingni
;
Wang, Hongjuan
;
Chen, Huan
;
Liu, Yong
;
Wang, An
收藏
  |  
浏览/下载:150/0
  |  
提交时间:2023/11/17
Acetaldehyde
Cytotoxicity
Genotoxicity
BEAS-2B cells
HHSteCs
MAPK/ERK
PI3K/AKT
Low Temperature Plasma Suppresses Lung Cancer Cells Growth via VEGF/VEGFR2/RAS/ERK Axis
期刊论文
MOLECULES, 2022, 卷号: 27
作者:
Zhou, Yuanyuan
;
Zhang, Yan
;
Bao, Jie
;
Chen, Jinwu
;
Song, Wencheng
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2022/12/22
low temperature plasma
lung cancer cell
ROS
RNS
cell death
EGPI-1, a novel eIF4E/eIF4G interaction inhibitor, inhibits lung cancer cell growth and angiogenesis through Ras/MNK/ERK/eIF4E signaling pathway
期刊论文
CHEMICO-BIOLOGICAL INTERACTIONS, 2022, 卷号: 352, 页码: 10
作者:
Qi, Xueju
;
Zhang, Shuna
;
Chen, Zekun
;
Wang, Lijun
;
Zhu, Wenyong
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2022/07/18
Human lung cancer
eIF4E
EGPI-1
Anticancer
Angiogenesis
Mitochondrial Calcium Disorder Affects Early Embryonic Development in Mice through Regulating the ERK/MAPK Pathway
期刊论文
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, 2022, 卷号: 2022
作者:
Zhang, LY
;
Liu, KX
;
Zhuan, QR
;
Liu, ZQ
;
Meng, L
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2022/12/02
Global identification of phospho-dependent SCF substrates reveals a FBXO22 phosphodegron and an ERK-FBXO22-BAG3 axis in tumorigenesis
期刊论文
CELL DEATH AND DIFFERENTIATION, 2021, 页码: 13
作者:
Liu, Ping
;
Cong, Xiaoji
;
Liao, Shengjie
;
Jia, Xinglong
;
Wang, Xiaomin
收藏
  |  
浏览/下载:79/0
  |  
提交时间:2021/08/17
P300/CBP inhibition sensitizes mantle cell lymphoma to PI3K delta inhibitor idelalisib
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:
Zhou, Xiao-ru
;
Li, Xiao
;
Liao, Li-ping
;
Han, Jie
;
Huang, Jing
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2021/06/11
mantle cell lymphoma
idelalisib
drug resistance
P300
CBP
synergistic drug action
PI3Kδ
epigenetics
P300/CBP inhibition sensitizes mantle cell lymphoma to PI3K delta inhibitor idelalisib
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:
Zhou, Xiao-ru
;
Li, Xiao
;
Liao, Li-ping
;
Han, Jie
;
Huang, Jing
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/06/11
mantle cell lymphoma
idelalisib
drug resistance
P300
CBP
synergistic drug action
PI3Kδ
epigenetics
Cediranib Induces Apoptosis, G1 Phase Cell Cycle Arrest, and Autophagy in Non-Small-Cell Lung Cancer Cell A549 In Vitro
期刊论文
BIOMED RESEARCH INTERNATIONAL, 2021, 卷号: 2021, 页码: 11
作者:
Guo, Menghuan
;
Liu, Zhiyuan
;
Si, Jing
;
Zhang, Jinhua
;
Zhao, Jin
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2021/12/10
Design, synthesis and pharmacological evaluation of bicyclic and tetracyclic pyridopyrimidinone analogues as new KRAS(G12C) inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 213, 页码: 17
作者:
Xiao, Xuanzheng
;
Lai, Mengzhen
;
Song, Zilan
;
Geng, Meiyu
;
Ding, Jian
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2021/05/24
KRAS
Covalent inhibitor
Pyridopyrimidinone
Antiproliferative effect
Scaffold hopping
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